Replication protein A interacts with AID to promote deamination of somatic hypermutation targets (Q31099047)

28 June 2017

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets (English)

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28 June 2017

Jayanta Chaudhuri

1

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28 June 2017

Chan Khuong

series ordinal

2

1 reference

28 June 2017

Frederick W Alt

series ordinal

3

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28 June 2017

language of work or name

English

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publication date

25 July 2004

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28 June 2017

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28 June 2017

430

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28 June 2017

992-998

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28 June 2017

7003

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Unraveling V(D)J recombination; insights into gene regulation

28 June 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Mechanism and control of class-switch recombination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Somatic hypermutation of immunoglobulin genes: merging mechanisms for genetic diversity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

The generation of antibody diversity through somatic hypermutation and class switch recombination

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Discriminating intrinsic and antigen-selected mutational hotspots in immunoglobulin V genes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Monitoring and interpreting the intrinsic features of somatic hypermutation

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Immunoglobulin genes: generating diversity with AID and UNG.

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Nucleic acid structures and enzymes in the immunoglobulin class switch recombination mechanism

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Transcription-coupled events associating with immunoglobulin switch region chromatin

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

AID mediates hypermutation by deaminating single stranded DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

The influence of transcriptional orientation on endogenous switch region function

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Progress in understanding the mechanism and consequences of somatic hypermutation

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

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https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Effects of Sequence and Structure on the Hypermutability of Immunoglobulin Genes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

AID mutant analyses indicate requirement for class-switch-specific cofactors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Replication of simian virus 40 origin-containing DNA in vitro with purified proteins

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Purification and characterization of replication protein A, a cellular protein required for in vitro replication of simian virus 40 DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Replication protein A confers structure-specific endonuclease activities to the XPF-ERCC1 and XPG subunits of human DNA repair excision nuclease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Palindromic but not G-rich sequences are targets of class switch recombination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Both DNA strands of antibody genes are hypermutation targets

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

The transcriptional regulator RfaH stimulates RNA chain synthesis after recruitment to elongation complexes by the exposed nontemplate DNA strand.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

The structural basis of the transition from initiation to elongation phases of transcription, as well as translocation and strand separation, by T7 RNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Antisense intergenic transcription in V(D)J recombination.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

A human RNA polymerase II complex associated with SRB and DNA-repair proteins

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Somatic hypermutation of the AID transgene in B and non-B cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02821

7 January 2021

Identifiers

DOI

10.1038/NATURE02821

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Dimensions Publication ID

28 June 2017

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