Mechanism and control of class-switch recombination (Q34500935)

2 August 2017

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title

Mechanism and control of class-switch recombination (English)

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2 August 2017

John P Manis

1

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PubMed ID

11801452

2 August 2017

Ming Tian

series ordinal

2

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PubMed ID

11801452

2 August 2017

Frederick W Alt

series ordinal

3

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2 August 2017

1 January 2002

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2 August 2017

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2 August 2017

23

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2 August 2017

31-39

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2 August 2017

1

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Factors and forces controlling V(D)J recombination

2 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Unique and unprecedented recombination mechanisms in class switching

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Towards an understanding of somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Nonhomologous end-joining proteins are required for V(D)J recombination, normal growth, and neurogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Molecular mechanism of immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Ig heavy chain class switching in Rag-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Germinal centers: form and function.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

IgA production without mu or delta chain expression in developing B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

The immunoglobulin class switch: beyond "accessibility".

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Shutdown of class switch recombination by deletion of a switch region control element.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

IgA class switch in I alpha exon-deficient mice. Role of germline transcription in class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

An expressed neo(r) cassette provides required functions of the 1gamma2b exon for class switching.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

The 3' IgH regulatory region: a complex structure in a search for a function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Position-dependent inhibition of class-switch recombination by PGK-neor cassettes inserted into the immunoglobulin heavy chain constant region locus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Ialpha exon-replacement mice synthesize a spliced HPRT-C(alpha) transcript which may explain their ability to switch to IgA. Inhibition of switching to IgG in these mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Elucidation of a downstream boundary of the 3' IgH regulatory region

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Identification of 3' alpha-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Germline transcription and recombination of a murine VDJmudeltagamma1 transgene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Evaluation of the role of the 3'alpha heavy chain enhancer [3'alpha E(hs1,2)] in Vh gene somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

A pivotal role for DNase I-sensitive regions 3b and/or 4 in the induction of somatic hypermutation of IgH genes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Immunoglobulin class switch recombination: will genetics provide new clues to mechanism?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

DNA sequences at immunoglobulin switch region recombination sites

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Microsites for immunoglobulin switch recombination breakpoints from Xenopus to mammals

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Palindromic but not G-rich sequences are targets of class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

The mu switch region tandem repeats are important, but not required, for antibody class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences

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https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Evidence for class-specific factors in immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Switch circular DNA formed in cytokine-treated mouse splenocytes: evidence for intramolecular DNA deletion in immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Circular DNA is excised by immunoglobulin class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Organization of immunoglobulin heavy chain genes and allelic deletion model

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Circular DNA is a product of the immunoglobulin class switch rearrangement

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Immunoglobulin heavy-chain expression and class switching in a murine leukaemia cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Regulation of the assembly and expression of variable-region genes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Ku70 is required for late B cell development and immunoglobulin heavy chain class switching

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Ku80 is required for immunoglobulin isotype switching

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

G4 DNA binding by LR1 and its subunits, nucleolin and hnRNP D, A role for G-G pairing in immunoglobulin switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

An extrachromosomal switch recombination substrate reveals kinetics and substrate requirements of switch recombination in primary murine B cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Switch transcripts in immunoglobulin class switching

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Processing of switch transcripts is required for targeting of antibody class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Induction of RNA-stabilized DMA conformers by transcription of an immunoglobulin switch region

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Copy choice mechanism of immunoglobulin heavy-chain switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Role of Saccharomyces cerevisiae Msh2 and Msh3 repair proteins in double-strand break-induced recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Frequent but biased class switch recombination in the S mu flanking regions.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

The molecular basis of somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Somatic hypermutation and the three R's: repair, replication and recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Somatic mutation of immunoglobulin lambda chains: a segment of the major intron hypermutates as much as the complementarity-determining regions

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Somatic hypermutation in the absence of DNA-dependent protein kinase catalytic subunit (DNA-PK(cs)) or recombination-activating gene (RAG)1 activity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Somatic hypermutation of an immunoglobulin mu heavy chain transgene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Cellular origin of human B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

DNA double strand break repair and chromosomal translocation: lessons from animal models

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

Molecular basis of genetic instability of triplet repeats

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4906%2801%2902111-1

7 January 2021

10.1016/S1471-4906(01)02111-1

Identifiers

DOI

1 reference

2 August 2017

1 reference

PubMed ID

11801452