Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila (Q30519991)

12 August 2017

Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila (English)

1 reference

Spiros Artavanis-Tsakonas

12 August 2017

0 references

5

object named as

Spyros Artavanis-Tsakonas

1 reference

12 August 2017

S K Pallavi

1

1 reference

12 August 2017

Diana M Ho

2

1 reference

12 August 2017

Chindo Hicks

3

1 reference

12 August 2017

Lucio Miele

4

1 reference

12 August 2017

language of work or name

English

0 references

publication date

11 May 2012

1 reference

12 August 2017

1 reference

12 August 2017

31

1 reference

12 August 2017

13

1 reference

12 August 2017

2895-2907

1 reference

Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signalling in solid tumours: a little bit of everything but not all the time

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

RANKL inhibition: a promising novel strategy for breast cancer treatment.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

MMP-1-PAR1 axis mediates LPA-induced epithelial ovarian cancer (EOC) invasion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch: the past, the present, and the future

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Targeting Notch to target cancer stem cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Identification of novel Notch target genes in T cell leukaemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The canonical Notch signaling pathway: unfolding the activation mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Disruption of Vps4 and JNK function in Drosophila causes tumour growth

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The Notch signaling pathway: transcriptional regulation at Notch target genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

MEF2: a central regulator of diverse developmental programs

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch activation stimulates transient and selective binding of Su(H)/CSL to target enhancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Character Changes Caused by Mutation of an Entire Region of a Chromosome in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signalling: a simple pathway becomes complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

A Temporal Map of Transcription Factor Activity: Mef2 Directly Regulates Target Genes at All Stages of Muscle Development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Exploring a new twist on tumor metastasis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Invasive cell behavior during Drosophila imaginal disc eversion is mediated by the JNK signaling cascade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The control of cell motility and epithelial morphogenesis by Jun kinases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

A Genetic Screen in Drosophila for Metastatic Behavior

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signaling and inherited disease syndromes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Inflammation and cancer: back to Virchow?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

MEF2: a transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

An activity of Notch regulates JNK signalling and affects dorsal closure in Drosophila.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signaling: cell fate control and signal integration in development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Boundary formation in Drosophila wing: Notch activity attenuated by the POU protein Nubbin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

wingless inhibits morphogenetic furrow movement in the Drosophila eye disc.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The relationship of decapentaplegic and engrailed expression in Drosophila imaginal disks: do these genes mark the anterior-posterior compartment boundary?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Notch signaling in leukemia

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Notch signaling directly controls cell proliferation in the Drosophila wing disc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Drosophila MEF2, a transcription factor that is essential for myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Integrated transcript and genome analyses reveal NKX2-1 and MEF2C as potential oncogenes in T cell acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Nodal points and complexity of Notch-Ras signal integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Requirement of MADS domain transcription factor D-MEF2 for muscle formation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutations within the conserved MADS box of the D-MEF2 muscle differentiation factor result in a loss of DNA binding ability and lethality in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Cell proliferation control by Notch signaling in Drosophila development.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Twist and Notch negatively regulate adult muscle differentiation in Drosophila.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

The wingless signalling pathway and the patterning of the wing margin in Drosophila.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3395089

Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing

26 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.129

TNF-alpha enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22580825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22580825

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2012.129

1 reference

12 August 2017

1 reference

12 August 2017

1 reference