The TBK1-binding domain of optineurin promotes type I interferon responses (Q28771750)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Ivana Munitic

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

author name string

Guozhi Zhu

2

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Maria Letizia Giardino Torchia

4

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Marie Pourcelot

5

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Damien Arnoult

6

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Paul R Mittelstadt

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

Jonathan D Ashwell

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

language of work or name

English

0 references

publication date

1 May 2016

1 reference

14 February 2017

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

volume

590

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

page(s)

1498-1508

1 reference

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3 June 2020

issue

10

2 references

14 February 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

3 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Adult-onset primary open-angle glaucoma caused by mutations in optineurin

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Identification of a transcription factor IIIA-interacting protein

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Mutations of optineurin in amyotrophic lateral sclerosis

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

A highly efficient recombineering-based method for generating conditional knockout mutations

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin regulates the interferon response in a cell cycle-dependent manner

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Structure and ubiquitination-dependent activation of TANK-binding kinase 1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Recent insights into the complexity of Tank-binding kinase 1 signaling networks: the emerging role of cellular localization in the activation and substrate specificity of TBK1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin with amyotrophic lateral sclerosis-related mutations abrogates inhibition of interferon regulatory factor-3 activation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Polyubiquitin binding to optineurin is required for optimal activation of TANK-binding kinase 1 and production of interferon β.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Optineurin and its mutants: molecules associated with some forms of glaucoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4879041

Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2F1873-3468.12176

Optineurin, a multifunctional protein involved in glaucoma, amyotrophic lateral sclerosis and antiviral signalling

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2F1873-3468.12176

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2F1873-3468.12176

Polyinosinic Acid Is a Ligand for Toll-like Receptor 3

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27086836

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Screening of OPTN in French familial amyotrophic lateral sclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27086836

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/1873-3468.12176

2 references

Consolidated OpenCitations Corpus – April 2017

4021566

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

4021566

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json

3 June 2020

2 references

Consolidated OpenCitations Corpus – April 2017

4021566

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27086836%20AND%20SRC:MED&resulttype=core&format=json