The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors (Q28771352)

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English	The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors	scientific journal article

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scholarly article

1 reference

14 February 2017

The serine protease plasmin cleaves the amino-terminal domain of the NR2A subunit to relieve zinc inhibition of the N-methyl-D-aspartate receptors (English)

1 reference

14 February 2017

author name string

Hongjie Yuan

1

1 reference

14 February 2017

Katie M. Vance

2

1 reference

14 February 2017

Candice E. Junge

3

1 reference

14 February 2017

Matthew T. Geballe

4

1 reference

14 February 2017

James P. Snyder

5

1 reference

14 February 2017

John R. Hepler

6

1 reference

14 February 2017

Manuel Yepes

7

1 reference

14 February 2017

Chian-Ming Low

8

1 reference

14 February 2017

Stephen F. Traynelis

9

1 reference

14 February 2017

language of work or name

0 references

publication date

8 May 2009

1 reference

14 February 2017

Journal of Biological Chemistry

1 reference

14 February 2017

284

1 reference

14 February 2017

12862–12873

1 reference

14 February 2017

19

1 reference

14 February 2017

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

1 reference

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16 March 2017

Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors

1 reference

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16 March 2017

The glutamate receptor ion channels

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16 March 2017

The biochemical basis of zinc physiology

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7 April 2017

Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

1 reference

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3 June 2018

Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1.

1 reference

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3 June 2018

Thrombolytic toxicity: blood brain barrier disruption in human ischemic stroke

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3 June 2018

Zinc inhibition of rat NR1/NR2A N-methyl-D-aspartate receptors

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3 June 2018

Proteolytic cleavage of human chromogranin a containing naturally occurring catestatin variants: differential processing at catestatin region by plasmin

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White matter NMDA receptors: an unexpected new therapeutic target?

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Protease-activated receptor signaling: new roles and regulatory mechanisms

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Astrocytic control of synaptic NMDA receptors

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3 June 2018

NMDA receptor subunits: function and pharmacology.

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NMDA receptor antibodies predict adverse neurological outcome after cardiac surgery in high-risk patients.

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3 June 2018

Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors

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3 June 2018

Expression and characterization of soluble amino-terminal domain of NR2B subunit of N-methyl-D-aspartate receptor.

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3 June 2018

The neurobiology of zinc in health and disease

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3 June 2018

Fibrin-modifying serine proteases thrombin, tPA, and plasmin in ischemic stroke: a review

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Glutamate receptor gating.

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3 June 2018

Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors

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3 June 2018

Tissue plasminogen activator promotes the effects of corticotropin-releasing factor on the amygdala and anxiety-like behavior

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3 June 2018

Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling

1 reference

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3 June 2018

The tissue plasminogen activator-plasmin system participates in the rewarding effect of morphine by regulating dopamine release

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3 June 2018

The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia

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3 June 2018

Blood test detecting autoantibodies to N-methyl-D-aspartate neuroreceptors for evaluation of patients with transient ischemic attack and stroke.

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3 June 2018

Proteases involved in long-term potentiation

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3 June 2018

NMDA receptor pathways as drug targets

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3 June 2018

Proteolysis of the N-methyl-d-aspartate receptor by calpain in situ

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3 June 2018

Protease-activated receptors: how proteases signal to cells

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3 June 2018

Ifenprodil, a novel NMDA receptor antagonist: site and mechanism of action

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3 June 2018

Specific proteolysis of the NR2 subunit at multiple sites by calpain

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3 June 2018

The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

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3 June 2018

Proteolysis of the exodomain of recombinant protease-activated receptors: prediction of receptor activation or inactivation by MALDI mass spectrometry.

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3 June 2018

Serine proteases and brain damage - is there a link?

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3 June 2018

The actions of synaptically released zinc at hippocampal mossy fiber synapses.

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3 June 2018

Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice

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3 June 2018

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit.

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Zinc and brain injury

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3 June 2018

Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

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Zinc metabolism in the brain: relevance to human neurodegenerative disorders

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3 June 2018

High-affinity zinc inhibition of NMDA NR1-NR2A receptors.

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3 June 2018

Plasmin-mediated proteolysis of osteocalcin

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3 June 2018

Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition.

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Clinical implications of the involvement of tPA in neuronal cell death

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3 June 2018

Possible involvement of plasmin in long-term potentiation of rat hippocampal slices.

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3 June 2018

Separating dual effects of zinc at recombinant N-methyl-D-aspartate receptors.

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Neuroprotective actions of excitatory amino acid receptor antagonists

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Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons.

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The action of zinc on synaptic transmission and neuronal excitability in cultures of mouse hippocampus

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3 June 2018

The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat neurones

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Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons

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Amino acid sequence studies on the α chain of human fibrinogen. Location of four plasmin attack points and a covalent cross-linking site

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3 June 2018

Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor.

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21 January 2018

Four residues of the extracellular N-terminal domain of the NR2A subunit control high-affinity Zn2+ binding to NMDA receptors.

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21 January 2018

Modulation of triheteromeric NMDA receptors by N-terminal domain ligands

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21 January 2018

Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit.

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Activation of pro-BDNF by the pericellular serine protease plasmin

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The micromolar zinc-binding domain on the NMDA receptor subunit NR2B.

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21 January 2018

Calpain-mediated regulation of NMDA receptor structure and function

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21 January 2018

A physiological role for endogenous zinc in rat hippocampal synaptic neurotransmission

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Acute tissue damage after injections of thrombin and plasmin into rat striatum.

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Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator.

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Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

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Plasmin converts factor X from coagulation zymogen to fibrinolysis cofactor

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19240037

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19240037

12 December 2020

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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