Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors. (Q44067007)

29 November 2017

Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors (English)

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12 May 2020

author name string

Florent Perin-Dureau

1

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12 May 2020

Julie Rachline

2

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12 May 2020

Jacques Neyton

3

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12 May 2020

Pierre Paoletti

4

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12 May 2020

language of work or name

English

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publication date

1 July 2002

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29 November 2017

Journal of Neuroscience

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12 May 2020

volume

22

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12 May 2020

page(s)

5955-5965

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12 May 2020

issue

14

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The glutamate receptor ion channels

12 May 2020

cites work

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12 December 2020

Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition.

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12 December 2020

Antagonists selective for NMDA receptors containing the NR2B subunit.

1 reference

12 December 2020

A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein

1 reference

12 December 2020

Subtype-specific assembly of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits is mediated by their n-terminal domains

1 reference

12 December 2020

Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor.

1 reference

12 December 2020

Oligomerization and ligand-binding properties of the ectodomain of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunit GluRD.

1 reference

12 December 2020

Four residues of the extracellular N-terminal domain of the NR2A subunit control high-affinity Zn2+ binding to NMDA receptors.

1 reference

12 December 2020

Molecular determinants of coordinated proton and zinc inhibition of N-methyl-D-aspartate NR1/NR2A receptors

1 reference

12 December 2020

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

1 reference

12 December 2020

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

1 reference

12 December 2020

Molecular organization of a zinc binding n-terminal modulatory domain in a NMDA receptor subunit.

1 reference

12 December 2020

Functional assembly of AMPA and kainate receptors is mediated by several discrete protein-protein interactions

1 reference

12 December 2020

Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state

1 reference

12 December 2020

Allosteric interaction between the amino terminal domain and the ligand binding domain of NR2A.

1 reference

12 December 2020

Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone

1 reference

12 December 2020

NMDA receptor antagonists as analgesics: focus on the NR2B subtype

1 reference

12 December 2020

Effect of zinc on NMDA receptor-mediated channel currents in cortical neurons

1 reference

12 December 2020

Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism.

1 reference

12 December 2020

Periplasmic binding protein structure and function. Refined X-ray structures of the leucine/isoleucine/valine-binding protein and its complex with leucine

1 reference

12 December 2020

Ifenprodil and SL 82.0715 as cerebral anti-ischemic agents. II. Evidence for N-methyl-D-aspartate receptor antagonist properties.

1 reference

12 December 2020

Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons.

1 reference

12 December 2020

Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins

1 reference

12 December 2020

Glycine-independent and subunit-specific potentiation of NMDA responses by extracellular Mg2+.

1 reference

12 December 2020

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1 reference

12 December 2020

Comparative protein modelling by satisfaction of spatial restraints

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12 December 2020

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

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12 December 2020

Molecular dissection of the agonist binding site of an AMPA receptor.

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12 December 2020

Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor

1 reference

12 December 2020

Atomic structure and specificity of bacterial periplasmic receptors for active transport and chemotaxis: variation of common themes

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12 December 2020

A novel mechanism of activity-dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones.

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12 December 2020

Influence of extracellular pH on inhibition by ifenprodil at N-methyl-D-aspartate receptors in Xenopus oocytes.

1 reference

12 December 2020

High-affinity zinc inhibition of NMDA NR1-NR2A receptors.

1 reference

12 December 2020

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives.

1 reference

12 December 2020

Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli: application of a novel protein folding screen

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12 December 2020

N-terminal domains in the NR2 subunit control desensitization of NMDA receptors.

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12 December 2020

Glycine-independent NMDA receptor desensitization: localization of structural determinants.

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12 December 2020

The structural aspects of limited proteolysis of native proteins

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12 December 2020

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit.

1 reference

12 December 2020

Structure-activity relationships for a series of bis(phenylalkyl)amines: potent subtype-selective inhibitors of N-methyl-D-aspartate receptors.

1 reference

12 December 2020

An allosteric interaction between the NMDA receptor polyamine and ifenprodil sites in rat cultured cortical neurones

1 reference

12 December 2020

Structure of a glutamate-receptor ligand-binding core in complex with kainate

1 reference

12 December 2020

10.1523/JNEUROSCI.22-14-05955.2002

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757916&resulttype=core&format=json

12 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757916&resulttype=core&format=json

12 May 2020

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