Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway (Q28680758)

24 June 2017

Rac1 is deactivated at integrin activation sites through an IQGAP1-filamin-A-RacGAP1 pathway (English)

1 reference

24 June 2017

0 references

Mark R Morgan

2

0 references

Adam Byron

Adam Byron

3

0 references

Guillaume Jacquemet

Guillaume Jacquemet

1

0 references

Jonathan D Humphries

Jonathan D Humphries

4

0 references

Martin J. Humphries

Martin J Humphries

8

0 references

Christopher S. Chen

6

Christopher S Chen

1 reference

24 June 2017

7

Patrick T Caswell

1 reference

24 June 2017

5

Colin K Choi

1 reference

24 June 2017

language of work or name

English

0 references

publication date

10 July 2013

1 reference

24 June 2017

Journal of Cell Science

1 reference

24 June 2017

126

1 reference

24 June 2017

Pt 18

1 reference

24 June 2017

4121-4135

1 reference

describes a project that uses

24 June 2017

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3772387/fullTextXML

inferred from PubMed Central ID database lookup

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17 March 2017

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17 March 2017

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17 March 2017

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7 April 2017

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7 April 2017

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7 April 2017

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3 June 2018

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BRCA2 localization to the midbody by filamin A regulates cep55 signaling and completion of cytokinesis

3 June 2018

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Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens

3 June 2018

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IQGAP1 mediates the disruption of adherens junctions to promote Escherichia coli K1 invasion of brain endothelial cells

3 June 2018

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Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A.

3 June 2018

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Rho protein crosstalk: another social network?

3 June 2018

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Angiopoietin-1 requires IQ domain GTPase-activating protein 1 to activate Rac1 and promote endothelial barrier defense

3 June 2018

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The IQGAP1 protein is a calmodulin-regulated barbed end capper of actin filaments: possible implications in its function in cell migration

3 June 2018

1 reference

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R-Ras interacts with filamin a to maintain endothelial barrier function

3 June 2018

1 reference

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Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins

3 June 2018

1 reference

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Distinct roles of septins in cytokinesis: SEPT9 mediates midbody abscission

3 June 2018

1 reference

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Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.

3 June 2018

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The NPIY motif in the integrin beta1 tail dictates the requirement for talin-1 in outside-in signaling

3 June 2018

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Focal adhesions are sites of integrin extension

3 June 2018

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PRIDE Converter: making proteomics data-sharing easy

3 June 2018

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Rac1 expression by fibroblasts is required for tissue repair in vivo

3 June 2018

1 reference

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ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway

3 June 2018

1 reference

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Linking integrin conformation to function

3 June 2018

1 reference

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Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis

3 June 2018

1 reference

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The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA.

3 June 2018

1 reference

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Synergistic control of cell adhesion by integrins and syndecans.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

IQGAP1 binds Rap1 and modulates its activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

Syndecan-4-dependent Rac1 regulation determines directional migration in response to the extracellular matrix

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1.

3 June 2018

1 reference

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Rac, membrane heterogeneity, caveolin and regulation of growth by integrins

3 June 2018

1 reference

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Polymerizing actin fibers position integrins primed to probe for adhesion sites

3 June 2018

1 reference

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IQGAP1 in cellular signaling: bridging the GAP.

3 June 2018

1 reference

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The molecular basis of filamin binding to integrins and competition with talin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

A Rac switch regulates random versus directionally persistent cell migration

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

Calmodulin regulates the post-anaphase reposition of centrioles during cytokinesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

Mitotic dissociation of IQGAP1 from Rac-bound beta1-integrin is mediated by protein phosphatase 2A.

3 June 2018

1 reference

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Interaction of filamin A with the integrin beta 7 cytoplasmic domain: role of alternative splicing and phosphorylation

3 June 2018

1 reference

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Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

A strategy for identifying gel-separated proteins in sequence databases by MS alone.

3 June 2018

1 reference

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Biologically active lipids are regulators of Rac.GDI complexation

3 June 2018

1 reference

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3 June 2018

1 reference

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Filamin A Regulates Monocyte Migration Through Rho Small GTPases During Osteoclastogenesis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3772387

Integrated network analysis platform for protein-protein interactions

27 November 2018

1 reference

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Regulation of protein phosphatase 2A-mediated recruitment of IQGAP1 to beta1 integrin by EGF through activation of Ca2+/calmodulin-dependent protein kinase II.

27 November 2018

1 reference

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Simple approach to micropattern cells on common culture substrates by tuning substrate wettability.

27 November 2018

1 reference

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Rng2p, a protein required for cytokinesis in fission yeast, is a component of the actomyosin ring and the spindle pole body.

27 November 2018

1 reference

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A method for reducing the time required to match protein sequences with tandem mass spectra

27 November 2018

1 reference

12 December 2020

Identification of a novel anti-integrin monoclonal antibody that recognises a ligand-induced binding site epitope on the β1 subunit

1 reference

12 December 2020

The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

1 reference

12 December 2020

IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.121988

1 reference

OpenCitations bibliographic resource ID

24 June 2017

4979442

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference