Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration (Q36368354)

13 August 2017

Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration (English)

1 reference

13 August 2017

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Raphaela Schwappacher

3

object named as

Raphaela Schwappacher

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author name string

Darren E Casteel

1

1 reference

13 August 2017

Stephanie Turner

2

1 reference

13 August 2017

Raphaela Schwappacher

3

1 reference

13 August 2017

Hema Rangaswami

4

1 reference

13 August 2017

Jacqueline Su-Yuo

5

1 reference

13 August 2017

Shunhui Zhuang

6

1 reference

13 August 2017

Gerry R Boss

7

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13 August 2017

Renate B Pilz

8

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13 August 2017

language of work or name

English

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publication date

19 September 2012

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Journal of Biological Chemistry

13 August 2017

12

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based on heuristic

inferred from page(s)

published in

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13 August 2017

287

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13 August 2017

45

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13 August 2017

38367-38378

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describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3488105/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance

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RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

30 September 2017

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Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts

30 September 2017

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Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers

30 September 2017

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IQGAPs in cancer: a family of scaffold proteins underlying tumorigenesis

30 September 2017

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Rho GTPase function in tumorigenesis

30 September 2017

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IQGAP1 regulation and roles in cancer

30 September 2017

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ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway

30 September 2017

1 reference

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Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection

30 September 2017

1 reference

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Specificity of Interactions between mDia Isoforms and Rho Proteins

30 September 2017

1 reference

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The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA.

30 September 2017

1 reference

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IQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cells

30 September 2017

1 reference

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Role of Rho GTPases in breast cancer

30 September 2017

1 reference

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Get to grips: steering local actin dynamics with IQGAPs

30 September 2017

1 reference

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Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors

30 September 2017

1 reference

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Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation

30 September 2017

1 reference

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Multiple proteins mediate IQGAP1-stimulated cell migration

30 September 2017

1 reference

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RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis

30 September 2017

1 reference

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Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

30 September 2017

1 reference

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Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma

30 September 2017

1 reference

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Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility

30 September 2017

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Rho-family GTPases: it's not only Rac and Rho (and I like it).

30 September 2017

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Molecular basis for Rho GTPase signaling specificity

30 September 2017

1 reference

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RhoC induces differential expression of genes involved in invasion and metastasis in MCF10A breast cells

30 September 2017

1 reference

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Positive role of IQGAP1, an effector of Rac1, in actin-meshwork formation at sites of cell-cell contact

30 September 2017

1 reference

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30 September 2017

RHO-GTPases and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Role for RhoB and PRK in the suppression of epithelial cell transformation by farnesyltransferase inhibitors

30 September 2017

1 reference

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Identification and characterization of a novel activated RhoB binding protein containing a PDZ domain whose expression is specifically modulated in thyroid cells by cAMP

30 September 2017

1 reference

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cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions

30 September 2017

1 reference

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IQGAP1 is a component of Cdc42 signaling to the cytoskeleton

30 September 2017

1 reference

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Rho regulates p21(CIP1), cyclin D1, and checkpoint control in mammary epithelial cells

30 September 2017

1 reference

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Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways

30 September 2017

1 reference

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RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

RhoC GTPase, a novel transforming oncogene for human mammary epithelial cells that partially recapitulates the inflammatory breast cancer phenotype.

30 September 2017

1 reference

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Genomic analysis of metastasis reveals an essential role for RhoC

30 September 2017

1 reference

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Gastric hyperplasia in mice lacking the putative Cdc42 effector IQGAP1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Characterization of the association of the actin-binding protein, IQGAP, and activated Cdc42 with Golgi membranes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

IQGAP1, a calmodulin-binding protein with a rasGAP-related domain, is a potential effector for cdc42Hs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

A role for Rho in Ras transformation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

IQGAP1 regulates cell proliferation through a novel CDC42-mTOR pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

IQGAP1 promotes cell motility and invasion

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Regulation of cGMP-dependent protein kinase expression by Rho and Kruppel-like transcription factor-4.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Oncogenic Ras leads to Rho activation by activating the mitogen-activated protein kinase pathway and decreasing Rho-GTPase-activating protein activity

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3488105

Both farnesylated and geranylgeranylated RhoB inhibit malignant transformation and suppress human tumor growth in nude mice

21 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22992742

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.377499

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

22992742

1 reference