Insulin receptor internalization and signalling (Q28616315)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0038014

insulin receptor internalization

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0038016

positive regulation of insulin receptor signaling pathway by insulin receptor internalization

1 reference

Gene Ontology release 2020-05-02

1 reference

G. M. Di Guglielmo

1

1 reference

3 February 2017

P. G. Drake

2

1 reference

3 February 2017

P. C. Baass

3

1 reference

3 February 2017

F. Authier

4

1 reference

3 February 2017

B. I. Posner

5

1 reference

3 February 2017

J. J. Bergeron

Molecular and Cellular Biochemistry

6

1 reference

3 February 2017

1 May 1998

1 reference

3 February 2017

1 reference

3 February 2017

182

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3 February 2017

59–63

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3 February 2017

1-2

1 reference

3 February 2017

Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures

1 reference

12 December 2020

An assessment of human insulin receptor phosphorylation and exogenous kinase activity following deletion of 69 residues from the carboxyl-terminus of the receptor beta-subunit

1 reference

12 December 2020

Purification, identification and subcellular distribution of three predominant protein-tyrosine phosphatase enzymes in skeletal muscle tissue

1 reference

12 December 2020

Internalization and activation of the rat liver insulin receptor kinase in vivo

1 reference

12 December 2020

Selective activation of the rat hepatic endosomal insulin receptor kinase. Role for the endosome in insulin signaling

1 reference

12 December 2020

Quantitative aspects of the insulin-receptor interaction in liver plasma membranes.

1 reference

12 December 2020

Receptor-mediated endocytosis of epidermal growth factor by hepatocytes in the perfused rat liver: ligand and receptor dynamics

1 reference

12 December 2020

Selective degradation of insulin within rat liver endosomes

1 reference

12 December 2020

Peroxovanadium compounds: biological actions and mechanism of insulin-mimesis.

1 reference

12 December 2020

Phosphorylation activates the insulin receptor tyrosine protein kinase

1 reference

12 December 2020

In vivo insulin mimetic effects of pV compounds: role for tissue targeting in determining potency

1 reference

12 December 2020

Insulin differentially regulates protein phosphotyrosine phosphatase activity in rat hepatoma cells

1 reference

12 December 2020

Acidification of the endocytic and exocytic pathways

1 reference

12 December 2020

Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics

1 reference

12 December 2020

Dynamic regulation of intact and C-terminal truncated insulin receptor phosphorylation in permeabilized cells

1 reference

12 December 2020

Insulin receptor kinase following internalization in isolated rat adipocytes

1 reference

12 December 2020

Insulin-degrading enzyme

1 reference

12 December 2020

Intracellular signal transduction: The role of endosomes

1 reference

12 December 2020

Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme

1 reference

12 December 2020

Insulin-receptor phosphotyrosyl-protein phosphatases

1 reference

12 December 2020

The dissociation and degradation of internalized insulin occur in the endosomes of rat hepatoma cells

1 reference

12 December 2020

Binding and uptake of 125I-insulin into rat liver hepatocytes and endothelium. An in vivo radioautographic study

1 reference

12 December 2020

Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo

1 reference

12 December 2020

Receptor-mediated endocytosis of asialoglycoproteins by rat liver hepatocytes: biochemical characterization of the endosomal compartments

1 reference

12 December 2020

Compartmentalized signal transduction by receptor tyrosine kinases

1 reference

12 December 2020

Uptake of insulin and other ligands into receptor-rich endocytic components of target cells: the endosomal apparatus

1 reference

12 December 2020

Control of EGF receptor signaling by clathrin-mediated endocytosis.

1 reference

12 December 2020

Degradation of the cleaved leader peptide of thiolase by a peroxisomal proteinase

1 reference

12 December 2020

Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle

1 reference

12 December 2020

Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma.

1 reference

12 December 2020

The insulin receptor C-terminus is involved in regulation of the receptor kinase activity

1 reference

12 December 2020

Dynamics of signaling during insulin-stimulated endocytosis of its receptor in adipocytes

1 reference

12 December 2020

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

12 December 2020

The dephosphorylation of insulin and epidermal growth factor receptors. Role of endosome-associated phosphotyrosine phosphatase(s)

1 reference

12 December 2020

Hepatic metabolism of glucagon in the dog: contribution of the liver to overall metabolic disposal of glucagon

1 reference

12 December 2020

Tyrosine phosphorylation of the insulin receptor during insulin-stimulated internalization in rat hepatoma cells.

1 reference

12 December 2020

Insulin-induced in situ phosphorylation of the insulin receptor located in the plasma membrane versus endosomes

1 reference

12 December 2020

Decrease in beta-subunit phosphotyrosine correlates with internalization and activation of the endosomal insulin receptor kinase

1 reference

12 December 2020

Serine/threonine kinases and tyrosine phosphatases that act on the insulin receptor

1 reference

12 December 2020

A role for tyrosine phosphorylation in both activation and inhibition of the insulin receptor tyrosine kinase in vivo

1 reference

12 December 2020