Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma. (Q40793167)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7925272%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

title

Compartmentalization of SHC, GRB2 and mSOS, and hyperphosphorylation of Raf-1 by EGF but not insulin in liver parenchyma (English)

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28 October 2019

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Di Guglielmo GM

1

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28 October 2019

Baass PC

2

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28 October 2019

Ou WJ

3

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28 October 2019

Posner BI

4

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28 October 2019

Bergeron JJ

5

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28 October 2019

language of work or name

English

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publication date

1 September 1994

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28 October 2019

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28 October 2019

volume

13

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28 October 2019

page(s)

4269-4277

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28 October 2019

issue

18

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Electron microscopic examination of subcellular fractions. I. The preparation of representative samples from suspensions of particles

28 October 2019

cites work

1 reference

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Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

24 September 2017

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The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling

24 September 2017

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Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

24 September 2017

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

24 September 2017

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

24 September 2017

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

24 September 2017

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A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos.

24 September 2017

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An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

24 September 2017

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Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

24 September 2017

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Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

24 September 2017

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The function of GRB2 in linking the insulin receptor to Ras signaling pathways

24 September 2017

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

24 September 2017

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Purification and characterization of epidermal growth factor receptor/protein kinase from normal mouse liver

24 September 2017

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Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polype

24 September 2017

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Autophosphorylation sites on the epidermal growth factor receptor.

24 September 2017

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The ultrastructural basis of capillary permeability studied with peroxidase as a tracer

24 September 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

24 September 2017

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Characterization of rat liver endosomal fractions. In vivo activation of insulin-stimulable receptor kinase in these structures

24 September 2017

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Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism

24 September 2017

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Biological effects of epidermal growth factor, with emphasis on the gastrointestinal tract and liver: an update

24 September 2017

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Ligand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization

24 September 2017

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Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo

24 September 2017

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All autophosphorylation sites of epidermal growth factor (EGF) receptor and HER2/neu are located in their carboxyl-terminal tails. Identification of a novel site in EGF receptor

24 September 2017

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Epidermal growth factor receptor kinase translocation and activation in vivo.

24 September 2017

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Selective degradation of insulin within rat liver endosomes

24 September 2017

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Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body

24 September 2017

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Analysis of deletions of the carboxyl terminus of the epidermal growth factor receptor reveals self-phosphorylation at tyrosine 992 and enhanced in vivo tyrosine phosphorylation of cell substrates

24 September 2017

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A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

24 September 2017

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

24 September 2017

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Epidermal growth factor stimulates tyrosine phosphorylation in the neonatal mouse: association of a M(r) 55,000 substrate with the receptor

24 September 2017

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Association of the tyrosine phosphorylated epidermal growth factor receptor with a 55-kD tyrosine phosphorylated protein at the cell surface and in endosomes

24 September 2017

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The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

24 September 2017

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Antiserum raised against a synthetic phosphotyrosine-containing peptide selectively recognizes p185neu/erbB-2 and the epidermal growth factor receptor

24 September 2017

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Galloylglucoses of low molecular weight as mordant in electron microscopy. I. Procedure, and evidence for mordanting effect

24 September 2017

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Ligand-induced internalization of the epidermal growth factor receptor is mediated by multiple endocytic codes analogous to the tyrosine motif found in constitutively internalized receptors

25 September 2017

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Effects of insulin on net carbohydrate alterations in perfused rat liver.

17 June 2018

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Differential and analytical subfractionation of rat liver components internalizing insulin and prolactin

17 June 2018

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Identification of a novel autophosphorylation site (P4) on the epidermal growth factor receptor

17 June 2018

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Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

17 June 2018

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TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

17 June 2018

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The dissociation and degradation of internalized insulin occur in the endosomes of rat hepatoma cells

17 June 2018

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ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

17 June 2018

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Signal transduction. How receptors turn Ras on.

17 June 2018

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Insulin-induced phosphorylation of the 46- and 52-kDa Shc proteins.

19 August 2018

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Polypeptide hormone receptors in vivo: demonstration of insulin binding to adrenal gland and gastrointestinal epithelium by quantitative radioautography

19 August 2018

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Quantitative aspects of the insulin-receptor interaction in liver plasma membranes.

19 August 2018

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Epidermal growth factor. Characteristics of specific binding in membranes from liver, placenta, and other target tissues

19 August 2018

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12 December 2020

Intracellular receptor sorting during endocytosis: Comparative immunoelectron microscopy of multiple receptors in rat liver

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12 December 2020

Internalization and activation of the rat liver insulin receptor kinase in vivo

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12 December 2020

Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase

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12 December 2020

Decrease in beta-subunit phosphotyrosine correlates with internalization and activation of the endosomal insulin receptor kinase

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12 December 2020

The dephosphorylation of insulin and epidermal growth factor receptors. Role of endosome-associated phosphotyrosine phosphatase(s)

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12 December 2020

Insulin-stimulated phosphatidylinositol 3-kinase. Association with a 185-kDa tyrosine-phosphorylated protein (IRS-1) and localization in a low density membrane vesicle

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Epidermal growth factor stimulates the tyrosine phosphorylation of SHC in the mouse

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12 December 2020

Interaction of activated EGF receptors with coated pit adaptins

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12 December 2020

Endosomal proteolysis of insulin by an acidic thiol metalloprotease unrelated to insulin degrading enzyme

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12 December 2020

Feedback regulation of mitogen-activated protein kinase kinase kinase activity of c-Raf-1 by insulin and phorbol ester stimulation

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12 December 2020

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7925272%20AND%20SRC:MED&resulttype=core&format=json

28 October 2019

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