Nibrin functions in Ig class-switch recombination (Q28594821)

1 February 2017

title

Nibrin functions in Ig class-switch recombination (English)

1 reference

1 February 2017

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GOA release 2020-03-11

author

Pierre-Olivier Frappart

object named as

Pierre-Olivier Frappart

4

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Ilja Demuth

object named as

Ilja Demuth

3

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Andreas Radbruch

10

object named as

Andreas Radbruch

1 reference

1 February 2017

Sven Kracker

1

1 reference

1 February 2017

Yvonne Bergmann

2

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1 February 2017

Gabriele Hildebrand

5

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1 February 2017

Rainer Christine

6

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1 February 2017

Zhao-Qi Wang

7

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1 February 2017

Karl Sperling

8

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1 February 2017

Martin Digweed

9

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1 February 2017

publication date

1 February 2005

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Proceedings of the National Academy of Sciences of the United States of America

1 February 2017

language of work or name

English

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published in

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1 February 2017

volume

102

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1 February 2017

issue

5

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1 February 2017

page(s)

1584–1589

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Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis

1 February 2017

cites work

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Targeted disruption of NBS1 reveals its roles in mouse development and DNA repair

17 March 2017

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Human Rad50/Mre11 is a flexible complex that can tether DNA ends

17 March 2017

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AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching

17 March 2017

1 reference

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17 March 2017

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Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=547877

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

17 March 2017

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Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

17 March 2017

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

17 March 2017

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Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.

17 March 2017

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Replication protein A interacts with AID to promote deamination of somatic hypermutation targets

29 September 2017

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Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=547877

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=547877

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

29 September 2017

1 reference

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Evidence for a direct association of hMRE11 with the human mismatch repair protein hMLH1.

29 September 2017

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Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells

29 September 2017

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A murine model of Nijmegen breakage syndrome

29 September 2017

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Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes

29 September 2017

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Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction

29 September 2017

1 reference

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Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination.

29 September 2017

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An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

29 September 2017

1 reference

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A mechanistic basis for Mre11-directed DNA joining at microhomologies

29 September 2017

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Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

29 September 2017

1 reference

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Processing of switch transcripts is required for targeting of antibody class switch recombination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=547877

B lymphocyte-specific, Cre-mediated mutagenesis in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=547877

High resolution banding analysis of the involvement of strain BALB/c- and AKR-derived chromosomes No. 15 in plasmacytoma-specific translocations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=547877

Class switch recombination is IgG1 specific on active and inactive IgH loci of IgG1-secreting B-cell blasts

29 September 2017

1 reference

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Rearrangement and expression of immunoglobulin light chain genes can precede heavy chain expression during normal B cell development in mice

29 September 2017

1 reference

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Shutdown of class switch recombination by deletion of a switch region control element.

3 June 2018

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Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice

3 June 2018

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https://api.crossref.org/works/10.1073%2FPNAS.0409191102

Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409191102

Decreased immunoglobulin class switching in nijmegen breakage syndrome due to the DNA repair defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409191102

Delineation of the role of the Mre11 complex in class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409191102

An inducible null mutant murine model of Nijmegen breakage syndrome proves the essential function of NBS1 in chromosomal stability and cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409191102

Staggered AID-dependent DNA double strand breaks are the predominant DNA lesions targeted to S mu in Ig class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0409191102

Immunoglobulin class switching: in vitro induction and analysis

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=547877

Alternative end joining during switch recombination in patients with ataxia-telangiectasia

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/15668383

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0409191102

1 reference

1 February 2017

0 references

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1 reference