Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons (Q28588398)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10479688%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

title

Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10479688%20AND%20SRC:MED&resulttype=core&format=json

BCL2-associated X protein

12 December 2019

main subject

apoptotic process

0 references

1 reference

GOA release 2020-03-11

Caspase 3

1 reference

GOA release 2020-03-11

author name string

S P Cregan

1

1 reference

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12 December 2019

J G MacLaurin

2

1 reference

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12 December 2019

C G Craig

3

1 reference

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12 December 2019

G S Robertson

4

1 reference

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12 December 2019

D W Nicholson

5

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12 December 2019

D S Park

6

1 reference

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12 December 2019

R S Slack

7

1 reference

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12 December 2019

language of work or name

English

0 references

publication date

1 September 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10479688%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

published in

Journal of Neuroscience

2 references

31 January 2017

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12 December 2019

volume

19

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31 January 2017

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12 December 2019

page(s)

7860-7869

1 reference

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12 December 2019

issue

18

2 references

31 January 2017

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Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

12 December 2019

cites work

1 reference

12 December 2020

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

1 reference

12 December 2020

p53-immunoreactive protein and p53 mRNA expression after transient middle cerebral artery occlusion in rats.

1 reference

12 December 2020

The Bcl-2 protein family: arbiters of cell survival

1 reference

12 December 2020

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

12 December 2020

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

1 reference

12 December 2020

Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death.

1 reference

12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

12 December 2020

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

12 December 2020

Life, death, and the pursuit of apoptosis.

1 reference

12 December 2020

Bax promotes neuronal cell death and is downregulated during the development of the nervous system.

1 reference

12 December 2020

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1 reference

12 December 2020

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

1 reference

12 December 2020

Effects of an Rb mutation in the mouse

1 reference

12 December 2020

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

12 December 2020

Transient global forebrain ischemia induces a prolonged expression of the caspase-3 mRNA in rat hippocampal CA1 pyramidal neurons.

1 reference

12 December 2020

Inhibition of cell-proliferation by an adenovirus vector expressing the human wild type-p53 protein.

1 reference

12 December 2020

Induction of CPP32-like activity in PC12 cells by withdrawal of trophic support. Dissociation from apoptosis

1 reference

12 December 2020

A role for the tumour suppressor gene p53 in regulating neuronal apoptosis

1 reference

12 December 2020

Redistribution of Bax from cytosol to membranes is induced by apoptotic stimuli and is an early step in the apoptotic pathway

1 reference

12 December 2020

Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat.

1 reference

12 December 2020

p53 expression induces apoptosis in hippocampal pyramidal neuron cultures.

1 reference

12 December 2020

Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures

1 reference

12 December 2020

Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress

1 reference

12 December 2020

Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats.

1 reference

12 December 2020

Activation of CPP32 during apoptosis of neurons and astrocytes

1 reference

12 December 2020

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1 reference

12 December 2020

Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.

1 reference

12 December 2020

Evidence for apoptotic cell death in Alzheimer's disease.

1 reference

12 December 2020

Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy.

1 reference

12 December 2020

T cells from baxalpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53.

1 reference

12 December 2020

Bax and Bak proteins require caspase activity to trigger apoptosis in sympathetic neurons

1 reference

12 December 2020

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

12 December 2020

Evidence for p53-mediated modulation of neuronal viability.

1 reference

12 December 2020

Hypoxia-induced apoptosis: effect of hypoxic severity and role of p53 in neuronal cell death.

1 reference

12 December 2020

Requirement for a functional Rb-1 gene in murine development

1 reference

12 December 2020

Mechanisms of p53-mediated apoptosis

1 reference

12 December 2020

Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways

1 reference

12 December 2020

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

1 reference

12 December 2020

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

12 December 2020

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis

1 reference

12 December 2020

Nuclear accumulation of p53 protein following kainic acid-induced seizures.

1 reference

12 December 2020

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

12 December 2020

Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death

1 reference

12 December 2020

Hippocampal Myc and p53 expression following transient global ischemia

1 reference

12 December 2020

Checkpoints of dueling dimers foil death wishes

1 reference

12 December 2020

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

12 December 2020

Apoptosis in the pathogenesis and treatment of disease

1 reference

12 December 2020

Evidence for involvement of Bax and p53, but not caspases, in radiation-induced cell death of cultured postnatal hippocampal neurons.

1 reference

12 December 2020

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

1 reference

12 December 2020

Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons

1 reference

12 December 2020

Induction of tumour-suppressor phosphoprotein p53 in the apoptosis of cultured rat cerebellar neurones triggered by excitatory amino acids.

1 reference

12 December 2020

p53: puzzle and paradigm

1 reference

12 December 2020

Regulated targeting of BAX to mitochondria.

1 reference

12 December 2020

Attenuation of p53 expression protects against focal ischemic damage in transgenic mice

1 reference

12 December 2020

Bax involvement in p53-mediated neuronal cell death

1 reference

12 December 2020

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

12 December 2020

Viral vectors for modulating gene expression in neurons

1 reference

12 December 2020

Cell death during development of the nervous system

1 reference

12 December 2020

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1 reference

12 December 2020

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells.

1 reference

12 December 2020

Caspases: enemies within

1 reference

12 December 2020

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

12 December 2020

Programmed cell death in the developing nervous system

1 reference

12 December 2020

Bcl-2 gene family in the nervous system

1 reference

12 December 2020

Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo

1 reference

12 December 2020

Analysis of events leading to neuronal death after infection with E1-deficient adenoviral vectors.

1 reference

12 December 2020

An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat.

1 reference

12 December 2020

p53 expression in brain after middle cerebral artery occlusion in the rat

1 reference

12 December 2020

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis.

1 reference

12 December 2020

Evidence of apoptotic cell death after experimental traumatic brain injury in the rat.

1 reference

12 December 2020

10.1523/JNEUROSCI.19-18-07860.1999

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10479688%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

12 December 2019

4057904

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10479688%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4057904