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BCL2-associated X protein (Q14905404)

From Wikidata
mammalian protein found in Mus musculus
  • apoptosis regulator BAX
  • uniprot:Q07813
  • Bax
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    English
    BCL2-associated X protein
    mammalian protein found in Mus musculus
    • apoptosis regulator BAX
    • uniprot:Q07813
    • Bax

    Statements

    molecular function
    protein homodimerization activity
    determination method or standard
    IPI
    IEA
    IMP
    ISO
    5 references
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    27 February 2018
    stated in
    Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    27 February 2018
    stated in
    Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    27 February 2018
    stated in
    Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    protein binding
    determination method or standard
    IPI
    11 references
    retrieved
    8 April 2019
    stated in
    BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Bcl-2 family interaction with the mitochondrial morphogenesis machinery
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    BID: a novel BH3 domain-only death agonist
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Upregulation of Bcl2 inhibits apoptosis-driven BAX insertion but favors BAX relocalization in mitochondria
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains
    GOA
    curator
    HUGO Gene Nomenclature Committee
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    protein heterodimerization activity
    determination method or standard
    ISO
    IEA
    IPI
    7 references
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    27 February 2018
    stated in
    Bcl-XL and Bcl-2 repress a common pathway of cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    27 February 2018
    stated in
    Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    27 February 2018
    stated in
    Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    27 February 2018
    stated in
    BID: a novel BH3 domain-only death agonist
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    27 February 2018
    stated in
    Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    protein homodimerization activity
    determination method or standard
    IBA
    IEA
    IMP
    IPI
    ISO
    6 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IBA
    protein heterodimerization activity
    determination method or standard
    IBA
    IEA
    IPI
    ISO
    8 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    BID: a novel BH3 domain-only death agonist
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Bcl-XL and Bcl-2 repress a common pathway of cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IBA
    cell component
    cytosol
    determination method or standard
    IDA
    IEA
    ISO
    12 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Spatial and temporal changes in Bax subcellular localization during anoikis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Genetic inactivation of the transcription factor TIF-IA leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-alpha-induced liver injury
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Bax in Murine Thymus Is a Soluble Monomeric Protein That Displays Differential Detergent-induced Conformations
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    mitochondrion
    determination method or standard
    IDA
    IEA
    ISO
    15 references
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    27 February 2018
    stated in
    hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    The Bax N terminus is required for negative regulation by the mitogen-activated protein kinase kinase and Akt signaling pathways in T cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    A mitochondrial protein compendium elucidates complex I disease biology
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Caspases 3 and 7: key mediators of mitochondrial events of apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-alpha-induced liver injury
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Bcl-2 family interaction with the mitochondrial morphogenesis machinery
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    cytoplasm
    determination method or standard
    IDA
    IEA
    ISO
    10 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The Bax N terminus is required for negative regulation by the mitogen-activated protein kinase kinase and Akt signaling pathways in T cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Caspases 3 and 7: key mediators of mitochondrial events of apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Apoptosis in the pattern formation of the ventricular wall during mouse heart organogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    p53 and Bax: putative death factors in taste cell turnover
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Gustatory innervation and bax-dependent caspase-2: participants in the life and death pathways of mouse taste receptor cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    mitochondrion
    determination method or standard
    HDA
    IDA
    IEA
    ISO
    15 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The Bax N terminus is required for negative regulation by the mitogen-activated protein kinase kinase and Akt signaling pathways in T cells
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-alpha-induced liver injury
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Bcl-2 family interaction with the mitochondrial morphogenesis machinery
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    BI-1 regulates an apoptosis pathway linked to endoplasmic reticulum stress
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Caspases 3 and 7: key mediators of mitochondrial events of apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    HDA
    retrieved
    8 April 2019
    stated in
    A mitochondrial protein compendium elucidates complex I disease biology
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    HDA
    mitochondrial outer membrane
    determination method or standard
    IBA
    IDA
    IEA
    ISO
    7 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Spatial and temporal changes in Bax subcellular localization during anoikis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Cidea-deficient mice have lean phenotype and are resistant to obesity
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IBA
    biological process
    positive regulation of neuron apoptotic process
    determination method or standard
    IGI
    IEA
    IMP
    ISO
    20 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    BAX is required for neuronal death after trophic factor deprivation and during development
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Development of pontine noradrenergic A5 neurons requires brain-derived neurotrophic factor
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Effects of Bax gene deletion on muscle and motoneuron degeneration in a sexually dimorphic neuromuscular system
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Widespread Elimination of Naturally Occurring Neuronal Death inBax-Deficient Mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Differences in bcl-2- and bax-independent function in regulating apoptosis in sensory neuron populations
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Neuromuscular development in the absence of programmed cell death: phenotypic alteration of motoneurons and muscle
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Bcl-X(L)-caspase-9 interactions in the developing nervous system: evidence for multiple death pathways
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Programmed cell death of adult-generated hippocampal neurons is mediated by the proapoptotic gene Bax
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Bax limits adult neural stem cell persistence through caspase and IP3 receptor activation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Reversible physiological alterations in sympathetic neurons deprived of NGF but protected from apoptosis by caspase inhibition or Bax deletion
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Bax inactivation in lurcher mutants rescues cerebellar granule cells but not purkinje cells or inferior olivary neurons
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    Subtle shifts in the ratio between pro- and antiapoptotic molecules after activation of corticosteroid receptors decide neuronal fate
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    activation of cysteine-type endopeptidase activity involved in apoptotic process
    determination method or standard
    IDA
    IGI
    IEA
    IMP
    ISO
    7 references
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    27 February 2018
    stated in
    Olfactory neurons in bax knockout mice are protected from bulbectomy-induced apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    Proapoptotic BAX and BAK control multiple initiator caspases
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    27 February 2018
    stated in
    Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    neuron apoptotic process
    determination method or standard
    IGI
    IMP
    9 references
    retrieved
    8 April 2019
    stated in
    Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Neuromuscular development after the prevention of naturally occurring neuronal death by Bax deletion
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Gamma protocadherins are required for synaptic development in the spinal cord
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Changes in Cortical and Striatal Neurons Predict Behavioral and Electrophysiological Abnormalities in a Transgenic Murine Model of Huntington's Disease
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    Differences in bcl-2- and bax-independent function in regulating apoptosis in sensory neuron populations
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    NMDA receptors promote survival in somatosensory relay nuclei by inhibiting Bax-dependent developmental cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    positive regulation of apoptotic process
    determination method or standard
    IDA
    IGI
    IEA
    IMP
    ISO
    16 references
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    27 February 2018
    stated in
    BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Decreased glucose transporter expression triggers BAX-dependent apoptosis in the murine blastocyst
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    The role of Bax in glutamate-induced nerve cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Radiation-induced gastric epithelial apoptosis occurs in the proliferative zone and is regulated by p53, bak, bax, and bcl-2
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    Bcl-2 and Bax function independently to regulate cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    27 February 2018
    stated in
    TRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    Susceptibility to metanephric apoptosis in bradykinin B2 receptor null mice via the p53-Bax pathway
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    27 February 2018
    stated in
    Mammalian prion protein suppresses Bax-induced cell death in yeast
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    release of cytochrome c from mitochondria
    determination method or standard
    IDA
    IGI
    IEA
    ISO
    8 references
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    27 February 2018
    stated in
    A stapled BID BH3 helix directly binds and activates BAX
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    27 February 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    27 February 2018
    stated in
    Bax directly induces release of cytochrome c from isolated mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Bax-induced cytochrome c release from mitochondria depends on alpha-helices-5 and -6
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    27 February 2018
    stated in
    Spatial and temporal changes in Bax subcellular localization during anoikis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q07813&geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    release of cytochrome c from mitochondria
    determination method or standard
    IBA
    IDA
    IEA
    IGI
    ISO
    9 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    A stapled BID BH3 helix directly binds and activates BAX
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Bax-induced cytochrome c release from mitochondria depends on alpha-helices-5 and -6
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Spatial and temporal changes in Bax subcellular localization during anoikis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Bax directly induces release of cytochrome c from isolated mitochondria
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IBA
    activation of cysteine-type endopeptidase activity involved in apoptotic process
    determination method or standard
    IEA
    IGI
    IMP
    ISO
    6 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    Olfactory neurons in bax knockout mice are protected from bulbectomy-induced apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    Proapoptotic BAX and BAK control multiple initiator caspases
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    mitochondrial fusion
    determination method or standard
    IBA
    IEA
    IGI
    ISO
    ISS
    6 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    Role of Bax and Bak in mitochondrial morphogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    The mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IBA
    positive regulation of apoptotic process
    determination method or standard
    IBA
    IDA
    IEA
    IGI
    IMP
    ISO
    17 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    ISO
    retrieved
    8 April 2019
    stated in
    BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q07813
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    The role of Bax in glutamate-induced nerve cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Radiation-induced gastric epithelial apoptosis occurs in the proliferative zone and is regulated by p53, bak, bax, and bcl-2
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Decreased glucose transporter expression triggers BAX-dependent apoptosis in the murine blastocyst
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Bcl-2 and Bax function independently to regulate cell death
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Susceptibility to metanephric apoptosis in bradykinin B2 receptor null mice via the p53-Bax pathway
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    Bax can antagonize Bcl-XL during etoposide and cisplatin-induced cell death independently of its heterodimerization with Bcl-XL
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    TRPM-2 expression and tunel staining in neurodegenerative diseases: studies in wobbler and rd mice
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IGI
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    Mammalian prion protein suppresses Bax-induced cell death in yeast
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q07813
    determination method or standard
    IBA

    Identifiers

     
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