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Adenomatous polyposis coli protein (Q21494863)

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mouse protein (annotated by UniProtKB/Swiss-Prot Q61315)
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    Adenomatous polyposis coli protein
    mouse protein (annotated by UniProtKB/Swiss-Prot Q61315)

      Statements

      instance of
      protein
      0 references
      part of
      molecular function
      beta-catenin binding
      determination method or standard
      IBA
      IDA
      IEA
      IPI
      ISO
      ISS
      6 references
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      UniProt
      UniProt protein ID
      Q61315
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      ISS
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      ISO
      retrieved
      14 February 2019
      stated in
      The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IPI
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      InterPro
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IEA
      retrieved
      14 February 2019
      stated in
      Apc1638T: a mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IDA
      retrieved
      14 February 2019
      stated in
      Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
      GOA
      curator
      GO Central
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IBA
      cell component
      biological process
      negative regulation of Wnt signaling pathway
      determination method or standard
      IGI
      IEA
      IMP
      9 references
      retrieved
      14 February 2019
      stated in
      Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Apc tumor suppressor gene is the "zonation-keeper" of mouse liver
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Disruption of early proximodistal patterning and AVE formation in Apc mutants
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Inactivation of Apc in the mouse prostate causes prostate carcinoma
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Deficiency of Mbd2 attenuates Wnt signaling
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      InterPro
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IEA
      negative regulation of cell population proliferation
      determination method or standard
      ISS
      IGI
      IEA
      IMP
      ISO
      68 references
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      UniProt
      UniProt protein ID
      Q61315
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      ISS
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      ISO
      retrieved
      14 February 2019
      stated in
      Tumor burden and clonality in multiple intestinal neoplasia mouse/normal mouse aggregation chimeras
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Inactivation of both APC alleles in human and mouse tumors
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Molecular genetics of ulcerative colitis-associated colon cancer in the interleukin 2- and beta(2)-microglobulin-deficient mouse
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      APC-dependent suppression of colon carcinogenesis by PPARgamma
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Genetic background affects susceptibility to mammary hyperplasias and carcinomas in Apc(min)/+ mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Genotype-phenotype correlation in murine Apc mutation: differences in enterocyte migration and response to sulindac
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      In utero and neonatal sensitivity of ApcMin/+ mice to radiation-induced intestinal neoplasia
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Dietary modulation of carcinoma development in a mouse model for human familial adenomatous polyposis
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Intestinal tumorigenesis in the Apc1638N mouse treated with aspirin and resistant starch for up to 5 months
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Differential dietary effects on colonic and small bowel neoplasia in C57BL/6J Apc Min/+ mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      T cell status influences colon tumor occurrence in min mice fed short chain fructo-oligosaccharides as a diet supplement
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      APC inhibits ERK pathway activation and cellular proliferation induced by RAS
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc(Min/+) mouse
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Myc deletion rescues Apc deficiency in the small intestine
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Tumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Localized gene action controlling intestinal neoplasia in mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Gastro-intestinal tumorigenesis in Smad4 mutant mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Deficiency of Mbd2 attenuates Wnt signaling
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Meta-analysis of gene expression in mouse preimplantation embryo development
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Plasminogen activator inhibitor-1 (Pai-1) blockers suppress intestinal polyp formation in Min mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Alpha-catenin is essential in intestinal adenoma formation
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Dnmt1N/+ reduces the net growth rate and multiplicity of intestinal adenomas in C57BL/6-multiple intestinal neoplasia (Min)/+ mice independently of p53 but demonstrates strong synergy with the modifier of Min 1(AKR) resistance allele
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Interleukin-6 and cachexia in ApcMin/+ mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Polyamine metabolism and tumorigenesis in the Apc(Min/+) mouse
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Absence of Post-translational Aspartyl β-Hydroxylation of Epidermal Growth Factor Domains in Mice Leads to Developmental Defects and an Increased Incidence of Intestinal Neoplasia
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Genetic evaluation of candidate genes for the Mom1 modifier of intestinal neoplasia in mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Prostaglandin E(2) promotes colorectal adenoma growth via transactivation of the nuclear peroxisome proliferator-activated receptor delta
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Enhanced intestinal adenomatous polyp formation in Pms2-/-;Min mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Chemoprevention of intestinal polyposis in the Apcdelta716 mouse by rofecoxib, a specific cyclooxygenase-2 inhibitor
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Acceleration of intestinal polyposis through prostaglandin receptor EP2 in Apc(Delta 716) knockout mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Deficiency of SPARC suppresses intestinal tumorigenesis in APCMin/+ mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Potent modulation of intestinal tumorigenesis in Apcmin/+ mice by the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Functional PKC in vivo analysis using deficient mouse models
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      The H19 locus acts in vivo as a tumor suppressor
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      A urokinase-type plasminogen activator deficiency diminishes the frequency of intestinal adenomas in ApcMin/+ mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Gastrointestinal tumorigenesis in Smad4 (Dpc4) mutant mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Mom1 is a semi-dominant modifier of intestinal adenoma size and multiplicity in Min/+ mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Suppression of polypogenesis in a new mouse strain with a truncated Apc(Delta474) by a novel COX-2 inhibitor, JTE-522
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Suppression of intestinal polyposis in Apc(delta 716) knockout mice by an additional mutation in the cytosolic phospholipase A(2) gene
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Deletion of the AU-rich RNA binding protein Apobec-1 reduces intestinal tumor burden in Apc(min) mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      InterPro
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IEA
      negative regulation of epithelial cell proliferation
      determination method or standard
      IGI
      IMP
      TAS
      5 references
      retrieved
      14 February 2019
      stated in
      Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      TAS
      retrieved
      14 February 2019
      stated in
      APC mutation and the crypt cycle in murine and human intestine
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      retrieved
      14 February 2019
      stated in
      The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc1638N mouse model
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IGI
      negative regulation of canonical Wnt signaling pathway
      determination method or standard
      IBA
      IMP
      ISO
      TAS
      6 references
      retrieved
      14 February 2019
      stated in
      Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      TAS
      retrieved
      14 February 2019
      stated in
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      ISO
      retrieved
      14 February 2019
      stated in
      Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene
      GOA
      curator
      Mouse Genome Informatics
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IMP
      retrieved
      14 February 2019
      stated in
      Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
      GOA
      curator
      GO Central
      reference URL
      http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61315
      determination method or standard
      IBA

      Identifiers

       
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                        Retrieved from "https://www.wikidata.org/w/index.php?title=Q21494863&oldid=1412219289"