Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c (Q28506197)

24 January 2017

title

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c (English)

1 reference

Cyclin-dependent kinase inhibitor 1B

24 January 2017

main subject

1 reference

Multiple endocrine neoplasia 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Orit Rozenblatt-Rosen

4

object named as

Orit Rozenblatt-Rosen

1 reference

24 January 2017

7

Matthew Meyerson

1 reference

24 January 2017

Satyajit K. Karnik

1

1 reference

24 January 2017

Christina M. Hughes

2

1 reference

24 January 2017

Xueying Gu

3

1 reference

24 January 2017

Graeme W. McLean

5

1 reference

24 January 2017

Yue Xiong

6

1 reference

24 January 2017

Seung K. Kim

8

1 reference

24 January 2017

language of work or name

English

0 references

publication date

11 October 2005

1 reference

Proceedings of the National Academy of Sciences of the United States of America

24 January 2017

published in

1 reference

24 January 2017

volume

102

1 reference

24 January 2017

issue

41

1 reference

24 January 2017

page(s)

14659–14664

1 reference

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

24 January 2017

cites work

1 reference

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Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

19 March 2017

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Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues

21 January 2018

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Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

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19 March 2017

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A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

19 March 2017

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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

19 March 2017

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Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

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19 March 2017

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

7 April 2017

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29 September 2017

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Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex

29 September 2017

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29 September 2017

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CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma

29 September 2017

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2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1253549

Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0503484102

Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice

21 January 2018

1 reference

12 December 2020

Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1

1 reference

12 December 2020

Cyclin-dependent kinase inhibitors

1 reference

12 December 2020

Targeting and conditional inactivation of the murine Men1 locus using the Cre recombinase: loxP system

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0503484102

1 reference

ADS bibcode

2005PNAS..10214659K

0 references

1 reference

1 reference

1 reference