MLL targets SET domain methyltransferase activity to Hox gene promoters (Q28609771)

3 February 2017

title

MLL targets SET domain methyltransferase activity to Hox gene promoters (English)

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Lysine (K)-specific methyltransferase 2A

3 February 2017

main subject

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GOA release 2020-03-11

6

C. David Allis

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3 February 2017

Scott D. Briggs

2

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author name string

Thomas A. Milne

1

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3 February 2017

Hugh W. Brock

3

1 reference

3 February 2017

Mary Ellen Martin

4

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3 February 2017

Denise Gibbs

5

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3 February 2017

Jay L. Hess

7

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3 February 2017

publication date

1 November 2002

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3 February 2017

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3 February 2017

volume

10

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3 February 2017

issue

5

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3 February 2017

page(s)

1107–1117

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

3 February 2017

cites work

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Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

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DNA methylation patterns and epigenetic memory

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Methylation-induced repression--belts, braces, and chromatin

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The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

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A long-range regulatory element of Hoxc8 identified by using the pClasper vector

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General transcription factors bind promoters repressed by Polycomb group proteins.

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The Polycomb group--no longer an exclusive club?

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Epigenetic inheritance of active chromatin after removal of the main transactivator

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Essential role of Drosophila Hdac1 in homeotic gene silencing

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Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites

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MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

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Transcription. Unlocking the gates to gene expression

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Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

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Histone methyltransferases, diet nutrients and tumour suppressors

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Translating the Histone Code

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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A homeotic mutation in the trithorax SET domain impedes histone binding

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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

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The many faces of histone lysine methylation

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Molecular genetics of acute promyelocytic leukemia.

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Effects ofHOX homeobox genes in blood cell differentiation

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Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

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Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation

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Binding of Trithorax and Polycomb proteins to the bithorax complex: dynamic changes during early Drosophila embryogenesis

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Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny

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Regulation of chromatin structure by site-specific histone H3 methyltransferases

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The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

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Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality

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Active genes are tri-methylated at K4 of histone H3

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A Drosophila Polycomb group complex includes Zeste and dTAFII proteins

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DNA methylation represses transcription in vivo

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Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes

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Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

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7 January 2021

Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

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ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex

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7 January 2021

Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.

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Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling

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Altered Hox expression and segmental identity in Mll-mutant mice

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MLL, a mammalian trithorax- group gene, functions as a transcriptional maintenance factor in morphogenesis

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7 January 2021

Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex

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7 January 2021

Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails

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7 January 2021