Deletion of CDKAL1 affects mitochondrial ATP generation and first-phase insulin exocytosis (Q28504788)

GOA release 2020-03-11

1 reference

1 reference

Mica Ohara-Imaizumi

1

1 reference

24 January 2017

Masashi Yoshida

2

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24 January 2017

Kyota Aoyagi

3

1 reference

24 January 2017

Taro Saito

4

1 reference

24 January 2017

Tadashi Okamura

5

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24 January 2017

Hitoshi Takenaka

6

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24 January 2017

Yoshihiro Akimoto

7

1 reference

24 January 2017

Yoko Nakamichi

8

1 reference

24 January 2017

Rieko Takanashi-Yanobu

9

1 reference

24 January 2017

Chiyono Nishiwaki

10

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24 January 2017

Hayato Kawakami

11

1 reference

24 January 2017

Norihiro Kato

12

1 reference

24 January 2017

Shin-ichi Hisanaga

13

1 reference

24 January 2017

Masafumi Kakei

14

1 reference

24 January 2017

Shinya Nagamatsu

Creative Commons Attribution 4.0 International

15

1 reference

24 January 2017

language of work or name

English

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publication date

9 December 2010

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24 January 2017

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24 January 2017

5

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24 January 2017

12

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24 January 2017

e15553

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24 January 2017

start time

9 December 2010

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis

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Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity

19 March 2017

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Developmental regulation of the proteolysis of the p35 cyclin-dependent kinase 5 activator by phosphorylation

19 March 2017

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Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor

19 March 2017

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Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice

19 March 2017

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

7 April 2017

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A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

7 April 2017

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Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

7 April 2017

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The GK rat beta-cell: a prototype for the diseased human beta-cell in type 2 diabetes?

29 September 2017

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The role for endoplasmic reticulum stress in diabetes mellitus

29 September 2017

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Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis

29 September 2017

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Mitochondria and endoplasmic reticulum: the lethal interorganelle cross-talk

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Cdk5-dependent regulation of glucose-stimulated insulin secretion.

29 September 2017

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Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells

29 September 2017

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ER stress and the unfolded protein response

29 September 2017

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Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells

29 September 2017

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Imaging exocytosis of single insulin secretory granules with evanescent wave microscopy: distinct behavior of granule motion in biphasic insulin release

29 September 2017

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Dominant role of sarcoendoplasmic reticulum Ca2+-ATPase pump in Ca2+ homeostasis and exocytosis in rat pancreatic beta-cells

29 September 2017

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TIRF imaging of docking and fusion of single insulin granule motion in primary rat pancreatic beta-cells: different behaviour of granule motion between normal and Goto-Kakizaki diabetic rat beta-cells

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Substrate-dependent changes in mitochondrial function, intracellular free calcium concentration and membrane channels in pancreatic beta-cells

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Suppressive Effect of Long Term Sulfonylurea Treatment on A, B, and D Cells of Normal Rat Pancreas*

2 June 2018

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Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps

2 June 2018

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Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

21 January 2018

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Enhanced activation of Ca2+/calmodulin-dependent protein kinase II upon downregulation of cyclin-dependent kinase 5-p35.

21 January 2018

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Dynamics of calcium clearance in mouse pancreatic beta-cells.

21 January 2018

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Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

21 January 2018

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Association of upregulated activity of K(ATP) channels with impaired insulin secretion in UCP1-expressing insulinoma cells

21 January 2018

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Exchangeable gene trap using the Cre/mutated lox system.

21 January 2018

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Intracellular ATP directly blocks K+ channels in pancreatic B-cells

27 November 2018

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Dual effects of ATP on K+ currents of mouse pancreatic beta-cells

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21151568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Metabolic, ionic, and secretory response to D-glucose in islets from rats with acquired or inherited non-insulin-dependent diabetes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21151568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nutrient augmentation of Ca2+-dependent and Ca2+-independent pathways in stimulus-coupling to insulin secretion can be distinguished by their guanosine triphosphate requirements: studies on rat pancreatic islets

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21151568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0015553

1 reference

1903318

ADS bibcode

2010PLoSO...515553O

0 references

1903318

1 reference

1 reference

1 reference