Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes (Q28680760)

3

Cecilia M Lindgren

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Rachel M Freathy

Rachel M Freathy

10

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Hana Lango Allen

Hana Lango

6

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Jeffrey Barrett

Jeffrey C Barrett

11

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Nicholas J. Timpson

Nicholas J Timpson

7

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Tim Frayling

Timothy M Frayling

4

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Michael N Weedon

Michael N Weedon

2

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Sian Ellard

Sian Ellard

14

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Mark McCarthy

Mark I McCarthy

26

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Andrew Tym Hattersley

27

Andrew T Hattersley

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Alexander S Doney

24

Alex S F Doney

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Andrew D Morris

23

Andrew D Morris

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Andrew P Morris

13

Andrew P Morris

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John R. B. Perry

8

John R B Perry

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author name string

Katherine S Elliott

5

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Nigel W Rayner

9

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Beverley Shields

12

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Christopher J Groves

15

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Lorna W Harries

16

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Jonathan L Marchini

17

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Katharine R Owen

18

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Beatrice Knight

19

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Lon R Cardon

20

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Mark Walker

21

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Graham A Hitman

on focus list of Wikimedia project

22

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publication date

1 June 2007

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language of work or name

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316

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issue

5829

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page(s)

1336-41

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ScienceSource

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cites work

A genome-wide association study identifies novel risk loci for type 2 diabetes

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Identification of a mammalian mitochondrial porphyrin transporter

17 March 2017

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Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity

17 March 2017

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Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

17 March 2017

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

17 March 2017

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

17 March 2017

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

17 March 2017

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A haplotype map of the human genome

22 April 2017

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Aligning multiple genomic sequences with the threaded blockset aligner

22 April 2017

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Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

7 April 2017

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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

22 April 2017

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A fine-scale map of recombination rates and hotspots across the human genome

7 April 2017

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p16INK4a induces an age-dependent decline in islet regenerative potential

7 April 2017

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Cdk5-dependent regulation of glucose-stimulated insulin secretion.

3 June 2018

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Type 2 diabetes: principles of pathogenesis and therapy

3 June 2018

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Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex.

3 June 2018

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3 June 2018

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Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

3 June 2018

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Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats

3 June 2018

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Hypoplasia of endocrine and exocrine pancreas in homozygous transgenic TGF-beta1.

3 June 2018

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Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1

27 November 2018

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Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice

27 November 2018

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Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

27 November 2018

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Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling

27 November 2018

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