A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates (Q28304600)

GOA release 2020-03-11

author name string

V I Bashkirov

1

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H Scherthan

2

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J A Solinger

3

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J M Buerstedde

4

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W D Heyer

An essential yeast gene with homology to the exonuclease-encoding XRN1/KEM1 gene also encodes a protein with exoribonuclease activity

5

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publication date

24 February 1997

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language of work or name

English

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published in

Journal of Cell Biology

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volume

136

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issue

4

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page(s)

761-73

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cites work

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Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis

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Disruption of the gene XRN1, coding for a 5'----3' exoribonuclease, restricts yeast cell growth

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Solution structure of an unusually stable RNA tetraplex containing G- and U-quartet structures

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Characterization of cDNA encoding mouse homolog of fission yeast dhp1+ gene: structural and functional conservation

20 March 2017

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A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes

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Structural features in eukaryotic mRNAs that modulate the initiation of translation

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Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript

7 April 2017

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Turnover mechanisms of the stable yeast PGK1 mRNA

7 April 2017

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mRNA stability in mammalian cells

7 April 2017

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Carbohydrate Metabolism During Ascospore Development in Yeast

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Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells

7 April 2017

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An essential component of the decapping enzyme required for normal rates of mRNA turnover

7 April 2017

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Processing of pre-ribosomal RNA in Saccharomyces cerevisiae

7 April 2017

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A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation

7 April 2017

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Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure

7 April 2017

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Macromolecular domains within the cell nucleus

7 April 2017

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Premature translational termination triggers mRNA decapping

7 April 2017

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Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus

7 April 2017

1 reference

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Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA

7 April 2017

1 reference

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Degradation of mRNA in eukaryotes

7 April 2017

1 reference

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Double-stranded RNA viruses of Saccharomyces cerevisiae.

7 April 2017

1 reference

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Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae.

29 September 2017

1 reference

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Identification of functional domains in the Sep1 protein (= Kem1, Xrn1), which is required for transition through meiotic prophase in Saccharomyces cerevisiae

29 September 2017

1 reference

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Evidence for interstrand quadruplex formation in the dimerization of human immunodeficiency virus 1 genomic RNA

29 September 2017

1 reference

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Localisation of splicing snRNPs in mammalian cells

29 September 2017

1 reference

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The search for the right partner: homologous pairing and DNA strand exchange proteins in eukaryotes

29 September 2017

1 reference

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G-quartet structures in telomeric DNA.

29 September 2017

1 reference

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Processing of eukaryotic ribosomal RNA.

29 September 2017

1 reference

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Long-range RNA interaction of two sequence elements required for endonucleolytic cleavage of human insulin-like growth factor II mRNAs.

29 September 2017

1 reference

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Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease

29 September 2017

1 reference

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The intracellular localization of messenger RNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

A role of Sep1 (= Kem1, Xrn1) as a microtubule-associated protein in Saccharomyces cerevisiae.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Purification and characterization of an activity from Saccharomyces cerevisiae that catalyzes homologous pairing and strand exchange.

29 September 2017

1 reference

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kem mutations affect nuclear fusion in Saccharomyces cerevisiae

29 September 2017

1 reference

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rar mutations which increase artificial chromosome stability in Saccharomyces cerevisiae identify transcription and recombination proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Fragments of the internal transcribed spacer 1 of pre-rRNA accumulate in Saccharomyces cerevisiae lacking 5'----3' exoribonuclease 1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Cloning and characterization of DST2, the gene for DNA strand transfer protein beta from Saccharomyces cerevisiae

29 September 2017

1 reference

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Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

The rate-limiting step in yeast PGK1 mRNA degradation is an endonucleolytic cleavage in the 3'-terminal part of the coding region

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

An exoribonuclease from saccharomyces cerevisiae: Effect of modifications of 5′ end groups on the hydrolysis of substrates to 5′ mononucleotides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Control of messenger RNA stability in higher eukaryotes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Molecular analysis of the dhp1+ gene of Schizosaccharomyces pombe: an essential gene that has homology to the DST2 and RAT1 genes of Saccharomyces cerevisiae

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Replication occurs at discrete foci spaced throughout nuclei replicating in vitro.

2 June 2018

1 reference

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Preparation of extracts from higher eukaryotes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activities

2 June 2018

1 reference

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Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Tetramerization of an RNA oligonucleotide containing a GGGG sequence

2 June 2018

1 reference

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A single-stranded DNA exonuclease from Schizosaccharomyces pombe

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

Requirement of S. pombe exonuclease II, a homologue of S. cerevisiae Sep1, for normal mitotic growth and viability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2132493

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27 November 2018

1 reference

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