The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation (Q28242537)

16

Terje Espevik

0 references

Adriano Aguzzi

23

Adriano Aguzzi

0 references

Wolfgang Kastenmüller

24

Wolfgang Kastenmüller

0 references

Eicke Latz

25

Eicke Latz

0 references

author name string

Bernardo S Franklin

1

0 references

Lukas Bossaller

2

0 references

Dominic De Nardo

3

0 references

Jacqueline M Ratter

4

0 references

Andrea Stutz

5

0 references

Gudrun Engels

6

0 references

Christoph Brenker

7

0 references

Mark Nordhoff

8

0 references

Sandra R Mirandola

9

0 references

Ashraf Al-Amoudi

10

0 references

Matthew S Mangan

11

0 references

Sebastian Zimmer

12

0 references

Brian G Monks

13

0 references

Martin Fricke

14

0 references

Reinhold E Schmidt

15

0 references

Bernadette Jones

17

0 references

Andrew G Jarnicki

18

0 references

Philip M Hansbro

19

0 references

Patricia Busto

20

0 references

Ann Marshak-Rothstein

Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes

21

0 references

language of work or name

English

0 references

publication date

August 2014

0 references

published in

Nature Immunology

0 references

volume

15

0 references

page(s)

727-37

0 references

issue

8

0 references

cites work

1 reference

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20 March 2017

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Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

20 March 2017

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The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

20 March 2017

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IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice

20 March 2017

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MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

20 March 2017

1 reference

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CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

20 March 2017

1 reference

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

20 March 2017

1 reference

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Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

20 March 2017

1 reference

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Active caspase-1 is a regulator of unconventional protein secretion

20 March 2017

1 reference

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The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

20 March 2017

1 reference

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Gout-associated uric acid crystals activate the NALP3 inflammasome

20 March 2017

1 reference

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20 March 2017

1 reference

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ASC, a novel 22-kDa protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells

20 March 2017

1 reference

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CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

20 March 2017

1 reference

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Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury

20 March 2017

1 reference

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A molecular platform in neurons regulates inflammation after spinal cord injury

20 March 2017

1 reference

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Activation and regulation of the inflammasomes

20 March 2017

1 reference

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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

7 April 2017

1 reference

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

7 April 2017

1 reference

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Pyroptosis: host cell death and inflammation

7 April 2017

1 reference

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

7 April 2017

1 reference

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Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

7 April 2017

1 reference

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Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

The immunobiology of prion diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease

29 September 2017

1 reference

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ASC speck formation as a readout for inflammasome activation

29 September 2017

1 reference

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Higher-order assemblies in a new paradigm of signal transduction

29 September 2017

1 reference

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Cell-to-cell propagation of infectious cytosolic protein aggregates

29 September 2017

1 reference

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A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis

29 September 2017

1 reference

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The CARD plays a critical role in ASC foci formation and inflammasome signalling

29 September 2017

1 reference

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Cellular mechanisms of protein aggregate propagation

29 September 2017

1 reference

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Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome: clinical article

29 September 2017

1 reference

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A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen spread

29 September 2017

1 reference

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Prion propagation, toxicity and degradation

29 September 2017

1 reference

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A splice variant of ASC regulates IL-1beta release and aggregates differently from intact ASC.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Expression of ASC in renal tissues of familial mediterranean fever patients with amyloidosis: postulating a role for ASC in AA type amyloid deposition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Assembly, purification, and assay of the activity of the ASC pyroptosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

The molecular basis of functional bacterial amyloid polymerization and nucleation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Toll-like receptors in systemic autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Immunoblotting for active caspase-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Assessment and quantification of crystal-induced lysosomal damage.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Activating the NLRP3 inflammasome using the amyloidogenic peptide IAPP.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Pristane-induced lupus as a model of human lupus arthritis: evolvement of autoantibodies, internal organ and joint inflammation.

27 November 2018

1 reference

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Beyond the prion principle

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4116676

Superoxide dismutase 1 regulates caspase-1 and endotoxic shock

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24952505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inflammasome-derived IL-1β production induces nitric oxide-mediated resistance to Leishmania.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNI.2913

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI.2913

1 reference

Dimensions Publication ID

511924

1050879714

0 references

511924

1 reference

1 reference

1 reference