The non-genomic crosstalk between PPAR-gamma ligands and ERK1/2 in cancer cell lines (Q28238709)

Europe PubMed Central

title

The non-genomic crosstalk between PPAR-gamma ligands and ERK1/2 in cancer cell lines (English)

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author name string

Efstathia Papageorgiou

1

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Nea Pitulis

2

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Pavlos Msaouel

3

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Peter Lembessis

4

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Michael Koutsilieris

Expert Opinion on Therapeutic Targets

5

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language of work or name

English

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publication date

August 2007

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published in

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volume

11

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issue

8

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page(s)

1071-85

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cites work

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Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site

21 January 2018

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Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARgamma

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Troglitazone and rosiglitazone induce apoptosis of vascular smooth muscle cells through an extracellular signal-regulated kinase-independent pathway

21 January 2018

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15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells

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Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma ) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its anti-tumorigenic activity.

21 January 2018

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MAP kinase cascades are activated in astrocytes and preadipocytes by 15-deoxy-Delta(12-14)-prostaglandin J(2) and the thiazolidinedione ciglitazone through peroxisome proliferator activator receptor gamma-independent mechanisms involving reactive ox

21 January 2018

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A potential role of 15-deoxy-delta(12,14)-prostaglandin J2 for induction of human articular chondrocyte apoptosis in arthritis.

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Dependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivation

21 January 2018

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A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma

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Differential effects of peroxisome proliferator activated receptor-gamma (PPAR gamma) ligands in proximal tubular cells: thiazolidinediones are partial PPAR gamma agonists

21 January 2018

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15-deoxy-Delta12,14-prostaglandin J2 induces renal epithelial cell death through NF-kappaB-dependent and MAPK-independent mechanism.

21 January 2018

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Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929.

21 January 2018

1 reference

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Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma) induces cell death through MAPK-dependent mechanism in osteoblastic cells

21 January 2018

1 reference

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Peroxisome proliferator-activated receptor-gamma ligands inhibit TGF-beta 1-induced fibronectin expression in glomerular mesangial cells

21 January 2018

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Signal transduction by the JNK group of MAP kinases

21 January 2018

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

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Mitogen-activated protein kinase pathways

21 January 2018

1 reference

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Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPAR(gamma) agonists: evidence for disparate functional effects which are independent of NF-(kappa)B and PPAR(gamma).

21 January 2018

1 reference

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Apoptosis induced by troglitazone is both peroxisome proliferator-activated receptor-gamma- and ERK-dependent in human non-small lung cancer cells.

21 January 2018

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The Akt pathway: molecular targets for anti-cancer drug development

21 January 2018

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Activation of peroxisome proliferator-activated receptor-gamma by troglitazone (TGZ) inhibits human lung cell growth.

21 January 2018

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Rosiglitazone suppresses human lung carcinoma cell growth through PPARgamma-dependent and PPARgamma-independent signal pathways

21 January 2018

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Suppression of prostaglandin E2 receptor subtype EP2 by PPARgamma ligands inhibits human lung carcinoma cell growth

21 January 2018

1 reference

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Activation and role of MAP kinases in 15d-PGJ2-induced apoptosis in the human pancreatic cancer cell line MIA PaCa-2.

21 January 2018

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Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells

21 January 2018

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Involvement of MEK-ERK signaling pathway in the inhibition of cell growth by troglitazone in human pancreatic cancer cells.

21 January 2018

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Troglitazone activates p21Cip/WAF1 through the ERK pathway in HCT15 human colorectal cancer cells

21 January 2018

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15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase sign

21 January 2018

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15-lipoxygenase-1 metabolites down-regulate peroxisome proliferator-activated receptor gamma via the MAPK signaling pathway

21 January 2018

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Beyond peroxisome proliferator-activated receptor gamma signaling: the multi-facets of the antitumor effect of thiazolidinediones

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

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Synergy between PPARgamma ligands and platinum-based drugs in cancer

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Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

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Chromosomal Localization and Partial Genomic Structure of the Human Peroxisome Proliferator Activated Receptor-Gamma (hPPARγ) Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.8.1071

Peroxisome proliterator-activated receptors, orphans with ligands and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.8.1071

Loss-of-Function Mutations in PPARγ Associated with Human Colon Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.8.1071