Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome (Q28209736)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Normal V(D)J recombination in cells from patients with Nijmegen breakage syndrome (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

Nijmegen breakage syndrome

6 November 2019

main subject

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

E Harfst

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

S Cooper

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

S Neubauer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

U Grawunder

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

language of work or name

English

0 references

publication date

1 October 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

issue

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

page(s)

915-929

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination

6 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Impaired p53-mediated DNA damage response, cell-cycle disturbance and chromosome aberrations in Nijmegen breakage syndrome lymphoblastoid cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Hairpin coding end opening is mediated by RAG1 and RAG2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Fibroblasts from ataxia telangiectasia (AT) and AT heterozygotes show an enhanced level of residual DNA double-strand breaks after low dose-rate gamma-irradiation as assayed by pulsed field gel electrophoresis

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Nijmegen breakage syndrome: consequences of defective DNA double strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Unequal signal and coding joint formation in human V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

V(D)J recombination activity in human hematopoietic cells: correlation with developmental stage and genome stability.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

The half-life of RAG-1 protein in precursor B cells is increased in the absence of RAG-2 expression

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Positional cloning of the gene for Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Cleavage at a V(D)J recombination signal requires only RAG1 and RAG2 proteins and occurs in two steps.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

A routine method for the establishment of permanent growing lymphoblastoid cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

In situ visualization of DNA double-strand break repair in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Expression and V(D)J recombination activity of mutated RAG-1 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Definition of a core region of RAG-2 that is functional in V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

DNA hairpin opening mediated by the RAG1 and RAG2 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Somatic generation of antibody diversity

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Initiation of V(D)J recombination in a cell-free system.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2801%2900008-6

7 January 2021

10.1016/S0161-5890(01)00008-6

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11282395%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference