PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition (Q28118735)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27451907%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

title

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition (English)

2 references

4 January 2017

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19 March 2020

1

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19 March 2020

Pedram Razavi

5

1 reference

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author name string

Haley Ellis

2

2 references

4 January 2017

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Ruzica Bago

3

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4 January 2017

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19 March 2020

Eneda Toska

4

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Srinivasaraghavan Kannan

7

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Maura Dickler

9

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19 March 2020

Sarat Chandarlapaty

10

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Edi Brogi

11

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19 March 2020

José Baselga

13

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19 March 2020

Maurizio Scaltriti

14

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4 January 2017

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19 March 2020

F Javier Carmona

6

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19 March 2020

Chandra S Verma

8

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Dario R Alessi

12

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publication date

21 July 2016

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19 March 2020

2 references

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19 March 2020

volume

30

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19 March 2020

issue

2

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19 March 2020

page(s)

229-242

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

19 March 2020

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29 September 2017

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Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Schizosaccharomyces pombe AGC family kinase Gad8p forms a conserved signaling module with TOR and PDK1-like kinases

29 September 2017

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Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1.

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27 November 2018

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Identifiers

DOI

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19 March 2020

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