Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). (Q27931672)

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English	Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).	scientific article

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scholarly article

1 reference

1 December 2016

Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). (English)

1 reference

1 December 2016

Saccharomyces cerevisiae

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Guanine nucleotide-binding protein subunit alpha YHR005C

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GOA release 2020-03-11

GTPase-activating protein SST2 YLR452C

1 reference

GOA release 2020-03-11

William E. Courchesne

4

object named as

W E Courchesne

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author name string

H G Dohlman

1

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J Song

2

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D Ma

3

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J Thorner

5

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language of work or name

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publication date

September 1996

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Molecular and Cellular Biology

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1 December 2016

16

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5194-209

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9

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Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

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20 March 2017

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain

1 reference

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20 March 2017

Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3.

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Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain

1 reference

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Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity

1 reference

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Genetic identification of residues involved in association of alpha and beta G-protein subunits

1 reference

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20 March 2017

Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast

1 reference

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20 March 2017

MAP kinase pathways in yeast: for mating and more

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Inhibition of G-protein signaling by dominant gain-of-function mutations in Sst2p, a pheromone desensitization factor in Saccharomyces cerevisiae

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Ras membrane targeting is essential for glucose signaling but not for viability in yeast

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Physiological characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones

1 reference

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Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone

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Yeast α factor is processed from a larger precursor polypeptide: The essential role of a membrane-bound dipeptidyl aminopeptidase

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Transformation of intact yeast cells treated with alkali cations

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The Saccharomyces cerevisiae BAR1 gene encodes an exported protein with homology to pepsin

1 reference

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GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

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The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae

1 reference

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Pheromonal regulation and sequence of the Saccharomyces cerevisiae SST2 gene: a model for desensitization to pheromone

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Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

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S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein.

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Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling

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The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins

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Regulation of the yeast pheromone response pathway by G protein subunits

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Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway

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Mutations in the guanine nucleotide-binding domains of a yeast G alpha protein confer a constitutive or uninducible state to the pheromone response pathway

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The GTPase superfamily: conserved structure and molecular mechanism

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EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins

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GPA1Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae

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The yeast SCG1 gene: a G alpha-like protein implicated in the a- and alpha-factor response pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

Expression of MF alpha 1 in MATa cells supersensitive to alpha-factor leads to self-arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

Functional domains of a peptide hormone receptor: the alpha-factor receptor (STE2 gene product) of the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

Intracellular targeting and structural conservation of a prohormone-processing endoprotease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

Pheromone-induced phosphorylation of a G protein beta subunit in S. cerevisiae is associated with an adaptive response to mating pheromone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

Yeast alpha-mating factor receptor-linked G-protein signal transduction suppresses Ras-dependent activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

2 June 2018

Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

20 June 2018

Disruption of receptor-G protein coupling in yeast promotes the function of an SST2-dependent adaptation pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

27 November 2018

Overexpression of flbA, an early regulator of Aspergillus asexual sporulation, leads to activation of brlA and premature initiation of development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231520

27 November 2018

Constitutive mutants in the yeast pheromone response: ordered function of the gene products

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Micromanipulation and dissection of asci

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-myristoylation is required for function of the pheromone-responsive G alpha protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast α-mating factor receptor and G-protein-linked adenylyl cyclase inhibition requires RAS2 and GPA2 activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulating G protein signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The C-terminus of the S. cerevisiae alpha-pheromone receptor mediates an adaptive response to pheromone

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning of two types of GAP complementary DNA from human placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of the turn-off reaction for the hormone-activated adenylate cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast cells recover from mating pheromone alpha factor-induced division arrest by desensitization in the absence of alpha factor destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid sequence of retinal transducin at the site ADP-ribosylated by cholera toxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8756677

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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