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Guanine nucleotide-binding protein subunit alpha YHR005C (Q27549729)

From Wikidata

fungal protein found in Saccharomyces cerevisiae S288c

YHR005C
GPA1
guanine nucleotide-binding protein subunit alpha

Language	Label	Description	Also known as
default for all languages	No label defined
English	Guanine nucleotide-binding protein subunit alpha YHR005C	fungal protein found in Saccharomyces cerevisiae S288c	YHR005C GPA1 guanine nucleotide-binding protein subunit alpha

Statements

1 reference

25 May 2022

UniProt protein ID

G protein alpha subunit, helical insertion

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08539

Fungal G-protein, alpha subunit

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08539

P-loop containing nucleoside triphosphate hydrolase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P08539

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

signal transducer activity

determination method or standard

GTPase activity

determination method or standard

3 references

5 June 2018

Mutations in the guanine nucleotide-binding domains of a yeast G alpha protein confer a constitutive or uninducible state to the pheromone response pathway

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

determination method or standard

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

determination method or standard

5 June 2018

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

determination method or standard

metal ion binding

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

nucleotide binding

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

guanyl nucleotide binding

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

protein binding

determination method or standard

9 references

9 May 2019

Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Genome-scale analysis reveals Sst2 as the principal regulator of mating pheromone signaling in the yeast Saccharomyces cerevisiae.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

The Leu-132 of the Ste4(Gbeta) subunit is essential for proper coupling of the G protein with the Ste2 alpha factor receptor during the mating pheromone response in yeast

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Genetic identification of residues involved in association of alpha and beta G-protein subunits

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

G-protein beta-subunit binding

determination method or standard

1 reference

9 May 2019

Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

GTPase activity

determination method or standard

4 references

9 May 2019

Mutations in the guanine nucleotide-binding domains of a yeast G alpha protein confer a constitutive or uninducible state to the pheromone response pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

heterotrimeric G-protein complex

determination method or standard

4 references

5 June 2018

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

determination method or standard

5 June 2018

Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

determination method or standard

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

determination method or standard

5 June 2018

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

Saccharomyces Genome Database ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P08539&geneProductId=UniProtKB:P08539

determination method or standard

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

endosome membrane

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

heterotrimeric G-protein complex

determination method or standard

5 references

9 May 2019

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Biochemical analysis of yeast G(alpha) mutants that enhance adaptation to pheromone.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

determination method or standard

1 reference

9 May 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

biological process

adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion

determination method or standard

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

determination method or standard

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

G protein-coupled receptor signaling pathway

determination method or standard

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

response to pheromone

determination method or standard

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

nuclear migration involved in conjugation with cellular fusion

determination method or standard

1 reference

9 May 2019

The mating-specific Galpha interacts with a kinesin-14 and regulates pheromone-induced nuclear migration in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

regulation of MAPK export from nucleus

determination method or standard

1 reference

9 May 2019

Effect of the pheromone-responsive G(alpha) and phosphatase proteins of Saccharomyces cerevisiae on the subcellular localization of the Fus3 mitogen-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

inositol lipid-mediated signaling

determination method or standard

1 reference

9 May 2019

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

karyogamy involved in conjugation with cellular fusion

determination method or standard

1 reference

9 May 2019

The mating-specific Galpha interacts with a kinesin-14 and regulates pheromone-induced nuclear migration in budding yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08539

determination method or standard

pheromone-dependent signal transduction involved in conjugation with cellular fusion

determination method or standard

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Saccharomyces Genome Database ID

1 reference

20 March 2022

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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