Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine (Q27672832)

10

0 references

Fiona H. Marshall

object named as

Fiona H Marshall

13

0 references

Christopher G. Tate

object named as

Christopher G Tate

11

0 references

author name string

Andrew S Doré

1

0 references

James C Errey

3

0 references

Irene Ng

4

0 references

Kaspar Hollenstein

5

0 references

Ben Tehan

6

0 references

Edward Hurrell

7

0 references

Kirstie Bennett

8

0 references

Miles Congreve

9

0 references

Malcolm Weir

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation

12

0 references

publication date

7 September 2011

0 references

published in

Structure

0 references

volume

19

0 references

page(s)

1283-93

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issue

9

0 references

cites work

1 reference

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20 March 2017

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Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

20 March 2017

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20 March 2017

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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist

20 March 2017

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Crystal structure of opsin in its G-protein-interacting conformation

20 March 2017

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Structure of a beta1-adrenergic G-protein-coupled receptor

20 March 2017

1 reference

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Crystal structure of squid rhodopsin

20 March 2017

1 reference

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

20 March 2017

1 reference

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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

20 March 2017

2 references

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20 March 2017

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Adenosine receptors as therapeutic targets

7 April 2017

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Crystal structure of rhodopsin: A G protein-coupled receptor

20 March 2017

1 reference

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Features and development of Coot

20 March 2017

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Integration, scaling, space-group assignment and post-refinement

20 March 2017

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20 March 2017

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Scaling and assessment of data quality

20 March 2017

1 reference

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20 March 2017

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20 March 2017

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Hydrophilic side chains in the third and seventh transmembrane helical domains of human A2A adenosine receptors are required for ligand recognition

20 March 2017

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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

20 March 2017

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G proteins: transducers of receptor-generated signals

20 March 2017

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Beta-arrestins and cell signaling

7 April 2017

1 reference

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Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

7 April 2017

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International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update

29 September 2017

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Preladenant, a novel adenosine A(2A) receptor antagonist for the potential treatment of parkinsonism and other disorders.

29 September 2017

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Xanthines as adenosine receptor antagonists

29 September 2017

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Recent progress in the discovery of adenosine A(2A) receptor antagonists for the treatment of Parkinson's disease.

29 September 2017

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The crystallographic structure of the human adenosine A2A receptor in a high-affinity antagonist-bound state: implications for GPCR drug screening and design

29 September 2017

1 reference

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Adenosine receptor modeling: what does the A2A crystal structure tell us?

29 September 2017

1 reference

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GPCR 3D homology models for ligand screening: lessons learned from blind predictions of adenosine A2a receptor complex

29 September 2017

1 reference

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Engineering G protein-coupled receptors to facilitate their structure determination.

29 September 2017

1 reference

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Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.

29 September 2017

1 reference

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Thermostabilization of the neurotensin receptor NTS1.

29 September 2017

1 reference

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Evaluation of homology modeling of G-protein-coupled receptors in light of the A(2A) adenosine receptor crystallographic structure.

29 September 2017

1 reference

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Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor

29 September 2017

1 reference

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Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732996

Caffeine analogs: biomedical impact

29 September 2017

1 reference

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Istradefylline, a novel adenosine A2A receptor antagonist, for the treatment of Parkinson's disease

29 September 2017

1 reference

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Principles: receptor theory in pharmacology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732996

The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2a selective adenosine receptor antagonist

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732996

Adenosine receptors and behavioral actions of methylxanthines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732996

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732996

Functional role of the "ionic lock"--an interhelical hydrogen-bond network in family A heptahelical receptors.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732996

Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3732996

Practical Considerations of Membrane Protein Instability during Purification and Crystallisation

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21885291

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.STR.2011.06.014

1 reference

1780445

1780445

1 reference

1 reference

1 reference