Crystal structure of the amyloid-β p3 fragment provides a model for oligomer formation in Alzheimer's disease (Q27666598)

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21 January 2020

title

Crystal structure of the amyloid-β p3 fragment provides a model for oligomer formation in Alzheimer's disease (English)

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21 January 2020

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3

Colin L Masters

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author name string

Victor A Streltsov

1

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21 January 2020

Joseph N Varghese

2

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21 January 2020

Stewart D Nuttall

4

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21 January 2020

Colin L Masters

3

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21 January 2020

language of work or name

English

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publication date

1 January 2011

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21 January 2020

published in

Journal of Neuroscience

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21 January 2020

volume

31

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21 January 2020

issue

4

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21 January 2020

page(s)

1419-1426

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XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

21 January 2020

cites work

1 reference

12 December 2020

Review: model peptides and the physicochemical approach to beta-amyloids

1 reference

12 December 2020

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

1 reference

12 December 2020

Solid-state nuclear magnetic resonance techniques for structural studies of amyloid fibrils

1 reference

12 December 2020

Immunoglobulin VH domains and beyond: design and selection of single-domain binding and targeting reagents

1 reference

12 December 2020

Photoaffinity cross-linking of Alzheimer's disease amyloid fibrils reveals interstrand contact regions between assembled beta-amyloid peptide subunits

1 reference

12 December 2020

Mutations that reduce aggregation of the Alzheimer's Abeta42 peptide: an unbiased search for the sequence determinants of Abeta amyloidogenesis

1 reference

12 December 2020

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

1 reference

12 December 2020

Alzheimer beta-amyloid homodimers facilitate A beta fibrillization and the generation of conformational antibodies

1 reference

12 December 2020

Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

1 reference

12 December 2020

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

12 December 2020

Structural evidence for evolution of shark Ig new antigen receptor variable domain antibodies from a cell-surface receptor

1 reference

12 December 2020

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

1 reference

12 December 2020

Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

1 reference

12 December 2020

Capturing intermediate structures of Alzheimer's beta-amyloid, Abeta(1-40), by solid-state NMR spectroscopy

1 reference

12 December 2020

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

1 reference

12 December 2020

Structure of amyloid beta fragments in aqueous environments

1 reference

12 December 2020

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

1 reference

12 December 2020

High-resolution atomic force microscopy of soluble Abeta42 oligomers

1 reference

12 December 2020

Recent atomic models of amyloid fibril structure

1 reference

12 December 2020

Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

1 reference

12 December 2020

High resolution scanning tunnelling microscopy of the beta-amyloid protein (Abeta1-40) of Alzheimer's disease suggests a novel mechanism of oligomer assembly.

1 reference

12 December 2020

Delineating common molecular mechanisms in Alzheimer's and prion diseases

1 reference

12 December 2020

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

1 reference

12 December 2020

Beta-structures in fibrous proteins.

1 reference

12 December 2020

Abeta produced as a fusion to maltose binding protein can be readily purified and stably associates with copper and zinc.

1 reference

12 December 2020

A beta oligomers - a decade of discovery

1 reference

12 December 2020

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

1 reference

12 December 2020

Atomic structures of amyloid cross-beta spines reveal varied steric zippers

1 reference

12 December 2020

Molecular basis for passive immunotherapy of Alzheimer's disease

1 reference

12 December 2020

Familial Alzheimer's disease mutations alter the stability of the amyloid beta-protein monomer folding nucleus

1 reference

12 December 2020

Structure of an IgNAR-AMA1 complex: targeting a conserved hydrophobic cleft broadens malarial strain recognition

1 reference

12 December 2020

X-ray absorption and diffraction studies of the metal binding sites in amyloid beta-peptide

1 reference

12 December 2020

Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

1 reference

12 December 2020

Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs

1 reference

12 December 2020

Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope

1 reference

12 December 2020

Why is the amyloid beta peptide of Alzheimer's disease neurotoxic?

1 reference

12 December 2020

Role of the familial Dutch mutation E22Q in the folding and aggregation of the 15-28 fragment of the Alzheimer amyloid-beta protein.

1 reference

12 December 2020

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

12 December 2020

Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopy

1 reference

12 December 2020

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

12 December 2020

The structure of the amyloid-beta peptide high-affinity copper II binding site in Alzheimer disease

1 reference

12 December 2020

Aggregation and catabolism of disease-associated intra-Abeta mutations: reduced proteolysis of AbetaA21G by neprilysin

1 reference

12 December 2020

Non-electrostatic binding and self-association of amyloid beta-peptide on the surface of tightly packed phosphatidylcholine membranes.

1 reference

12 December 2020

Structural characterization of a soluble amyloid beta-peptide oligomer.

1 reference

12 December 2020

Seeded growth of beta-amyloid fibrils from Alzheimer's brain-derived fibrils produces a distinct fibril structure

1 reference

12 December 2020

Membrane charge dependent states of the beta-amyloid fragment Abeta (16-35) with differently charged micelle aggregates

1 reference

12 December 2020

1 reference

12 December 2020

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

1 reference

12 December 2020

Elucidation of amyloid beta-protein oligomerization mechanisms: discrete molecular dynamics study.

1 reference

12 December 2020

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

1 reference

12 December 2020

An improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studies

1 reference

12 December 2020

Identification of a beta-turn in the tertiary structure of a peptide fragment of the Alzheimer amyloid protein

1 reference

12 December 2020

Measurement of the attachment and assembly of small amyloid-β oligomers on live cell membranes at physiological concentrations using single-molecule tools.

1 reference

12 December 2020

CD measurements of β-amyloid (1-40) and (1-42) in the condensed phase

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Structural studies by X-ray diffraction of model lipid-protein membranes of serum albumin-lecithin-cardiolipin

1 reference

12 December 2020

Shape complementarity at protein/protein interfaces

1 reference

12 December 2020

P3 beta-amyloid peptide has a unique and potentially pathogenic immunohistochemical profile in Alzheimer's disease brain

1 reference

12 December 2020

VMD: visual molecular dynamics

1 reference

12 December 2020

The "nonamyloidogenic" p3 fragment (amyloid beta17-42) is a major constituent of Down's syndrome cerebellar preamyloid

1 reference

12 December 2020

Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.

1 reference

12 December 2020

10.1523/JNEUROSCI.4259-10.2011

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DOI

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Consolidated OpenCitations Corpus – April 2017

4697248

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21 January 2020

4697248

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Consolidated OpenCitations Corpus – April 2017

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21 January 2020

2 references

Consolidated OpenCitations Corpus – April 2017

4697248