Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation (Q27648499)

2

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Joel P Mackay

object named as

Joel P Mackay

3

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author name string

Corrine J Porter

1

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Sharon E Pursglove

4

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Jason W Schmidberger

5

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Peter J Leedman

6

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Stephanie C Pero

7

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David N Krag

8

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Matthew C J Wilce

https://scigraph.springernature.com/pub.10.1186/1472-6807-7-58

9

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publication date

25 September 2007

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published in

BMC Structural Biology

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volume

7

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issue

1

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page(s)

58

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exact match

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cites work

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NMR structure of the N-SH2 of the p85 subunit of phosphoinositide 3-kinase complexed to a doubly phosphorylated peptide reveals a second phosphotyrosine binding site

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Structural and conformational requirements for high-affinity binding to the SH2 domain of Grb2(1)

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Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3

20 March 2017

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Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7

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Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

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Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode

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Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

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Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

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Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor

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Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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SH2 domains recognize specific phosphopeptide sequences

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Calculation of protein extinction coefficients from amino acid sequence data

20 March 2017

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

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20 March 2017

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Cloning and characterization of GRB14, a novel member of the GRB7 gene family

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The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions

20 March 2017

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Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner

20 March 2017

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Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration

20 March 2017

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Association of focal adhesion kinase with Grb7 and its role in cell migration

20 March 2017

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20 March 2017

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Coexpression of Grb7 with epidermal growth factor receptor or Her2/erbB2 in human advanced esophageal carcinoma

20 March 2017

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Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus

20 March 2017

1 reference

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Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14

20 March 2017

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Combination treatment with Grb7 peptide and Doxorubicin or Trastuzumab (Herceptin) results in cooperative cell growth inhibition in breast cancer cells

20 March 2017

1 reference

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NMR analysis of G7-18NATE, a nonphosphorylated cyclic peptide inhibitor of the Grb7 adapter protein.

29 September 2017

1 reference

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New paradigms in anticancer therapy: targeting multiple signaling pathways with kinase inhibitors.

29 September 2017

1 reference

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Adapter protein connections: the MRL and Grb7 protein families

29 September 2017

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Inhibitors of growth factor signalling

29 September 2017

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The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

29 September 2017

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Backbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7-SH2/erbB2 peptide complex

29 September 2017

1 reference

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Grb10 and Grb14: enigmatic regulators of insulin action--and more?

29 September 2017

1 reference

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Intracellular signalling and cancer: complex pathways lead to multiple targets

29 September 2017

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Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads

29 September 2017

1 reference

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Grb7 in intracellular signaling and its role in cell regulation

29 September 2017

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Specificity in signal transduction: from phosphotyrosine-SH2 domain interactions to complex cellular systems

29 September 2017

1 reference

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Grb7-based molecular therapeutics in cancer

29 September 2017

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Tyrosine kinases as targets in cancer therapy - successes and failures

29 September 2017

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Molecular recognition by SH2 domains

29 September 2017

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Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7.

29 September 2017

1 reference

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Cancer cell motility--on the road from c-erbB-2 receptor steered signaling to actin reorganization

29 September 2017

1 reference

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Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.

29 September 2017

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The SH2 domain protein GRB-7 is co-amplified, overexpressed and in a tight complex with HER2 in breast cancer

29 September 2017

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Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques

29 September 2017

1 reference

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C. elegans cell migration gene mig-10 shares similarities with a family of SH2 domain proteins and acts cell nonautonomously in excretory canal development

29 September 2017

1 reference

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Specific peptide ligand for Grb7 signal transduction protein and pancreatic cancer metastasis.

2 June 2018

1 reference

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The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2131756

Alternative Modes of Tyrosyl Phosphopeptide Binding to a Src Family SH2 Domain: Implications for Regulation of Tyrosine Kinase Activity†

27 November 2018

1 reference

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EQUILIBRIUM ULTRACENTRIFUGATION OF DILUTE SOLUTIONS

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17894853

12 December 2020

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17894853

12 December 2020

inferred from PubMed ID database lookup

An efficient and cost-effective isotope labeling protocol for proteins expressed in Escherichia coli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17894853

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/1472-6807-7-58

1 reference

Dimensions Publication ID

1045477

1005054650

0 references

Fatcat ID

release_w3bmnfjxnvg5daiibgdzo55vay

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w3bmnfjxnvg5daiibgdzo55vay

24 November 2022

mapped directly with Wikidata item

1045477

1 reference

1 reference

1 reference