The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions (Q28199355)

The SH2-containing adapter protein GRB10 interacts with BCR-ABL

Europe PubMed Central

title

The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions (English)

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author name string

D C Han

series ordinal

1

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T L Shen

series ordinal

2

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J L Guan

series ordinal

3

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language of work or name

English

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publication date

1 October 2001

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published in

Oncogene

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volume

20

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page(s)

6315-21

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issue

44

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Cloning and characterization of GRB14, a novel member of the GRB7 gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Cloning, chromosome localization, expression, and characterization of an Src homology 2 and pleckstrin homology domain-containing insulin receptor binding protein hGrb10gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Inhibition of hGrb10 binding to the insulin receptor by functional domain-mediated oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Focal adhesion kinase in integrin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Association of focal adhesion kinase with Grb7 and its role in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Interaction between the Grb10 SH2 domain and the insulin receptor carboxyl terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Identification of the rat adapter Grb14 as an inhibitor of insulin actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Grb10/GrbIR as an in vivo substrate of Tec tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

C. elegans cell migration gene mig-10 shares similarities with a family of SH2 domain proteins and acts cell nonautonomously in excretory canal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Mutations affecting embryonic cell migrations in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

mGrb10 interacts with Nedd4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

The role of mGrb10alpha in insulin-like growth factor I-mediated growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Analysis of FAK-associated signaling pathways in the regulation of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

A novel variant of human Grb7 is associated with invasive esophageal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Sequence analysis identifies a ras-associating (RA)-like domain in the N-termini of band 4.1/JEF domains and in the Grb7/10/14 adapter family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

The Grb7 Family of Signalling Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

inferred from DOI database lookup

7 January 2021

based on heuristic

Expression of Grb7 growth factor receptor signaling protein in kidney development and in adult kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775

inferred from DOI database lookup

7 January 2021

based on heuristic

Grb7 signal transduction protein mediates metastatic progression of esophageal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204775