Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7. (Q31036345)

28 June 2017

Identification of novel non-phosphorylated ligands, which bind selectively to the SH2 domain of Grb7. (English)

1 reference

28 June 2017

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Roger J Daly

3

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author name string

Stephanie C Pero

1

1 reference

28 June 2017

Lyn Oligino

2

1 reference

28 June 2017

Amy L Soden

4

1 reference

28 June 2017

Chen Liu

5

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28 June 2017

Peter P Roller

6

1 reference

28 June 2017

Peng Li

7

1 reference

28 June 2017

David N Krag

8

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28 June 2017

language of work or name

English

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publication date

24 January 2002

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Journal of Biological Chemistry

28 June 2017

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28 June 2017

277

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28 June 2017

11918-11926

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28 June 2017

14

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The GRB family of SH2 domain proteins

28 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Potent inhibitory ligands of the GRB2 SH2 domain from recombinant peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Association of focal adhesion kinase with Grb7 and its role in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

A novel variant of human Grb7 is associated with invasive esophageal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Phage-displayed peptide libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Random peptide libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

The use of phage display for the development of tumour targeting agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Design, construction and function of a multicopy display vector using fusions to the major coat protein of bacteriophage M13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Peptide antagonists of the human estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Tumor targeting with a selective gelatinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Features of replicative senescence induced by direct addition of antennapedia-p16INK4A fusion protein to human diploid fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Structure-based design, synthesis, and X-ray crystallography of a high-affinity antagonist of the Grb2-SH2 domain containing an asparagine mimetic

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Searching for Peptide Ligands with an Epitope Library

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Peptides on phage: a vast library of peptides for identifying ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Enhancement of ELISAs for screening peptides in epitope phage display libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Selective enrichment and characterization of high affinity ligands from collections of random peptides on filamentous phage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Unexpected frameshifts from gene to expressed protein in a phage-displayed peptide library

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Peptides which bind to E-selectin and block neutrophil adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Small peptides as potent mimetics of the protein hormone erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Rapid identification of phosphopeptide ligands for SH2 domains. Screening of peptide libraries by fluorescence-activated bead sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Identification of phosphopeptide ligands for the Src-homology 2 (SH2) domain of Grb2 by phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Identification of novel peptide antagonists for GPIIb/IIIa from a conformationally constrained phage peptide library

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Prokaryotic expression cloning of a novel human tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Genetic engineering of proteins with cell membrane permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Tumor targeting using anti-her2 immunoliposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Ligands for the Tyrosine Kinase p56lckSH2 Domain: Discovery of Potent Dipeptide Derivatives with Monocharged, Nonhydrolyzable Phosphate Replacements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Nonphosphorylated peptide ligands for the Grb2 Src homology 2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Structure-based design and synthesis of a novel class of Src SH2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Potent dipeptide inhibitors of the pp60c-src SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Phosphotyrosine-containing dipeptides as high-affinity ligands for the p56lck SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Clinical significance of HER-2/neu oncogene amplification in primary breast cancer. The South Australian Breast Cancer Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Grb7 signal transduction protein mediates metastatic progression of esophageal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

L-O-(2-malonyl)tyrosine: a new phosphotyrosyl mimetic for the preparation of Src homology 2 domain inhibitory peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Potent antagonists of the SH2 domain of Grb2: optimization of the X+1 position of 3-amino-Z-Tyr(PO3H2)-X+1-Asn-NH2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

Immunoliposomes for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111816200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111816200

1 reference

28 June 2017

1 reference