RASSF tumor suppressor gene family: biological functions and regulation (Q26866080)

Marilyn Gordon

2

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Mohamed Salla

3

1 reference

Haya Abu Ghazaleh

4

1 reference

Shairaz Baksh

5

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language of work or name

1 reference

19 August 2014

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1 reference

588

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PubMed

page(s)

2671-84

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PubMed

issue

16

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RASSF1A: Not a prototypical Ras effector.

PubMed

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The pro-apoptotic Ras effector Nore1 may serve as a Ras-regulated tumor suppressor in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Rassf family of tumor suppressor polypeptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Functional importance of RASSF1A microtubule localization and polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

ATM regulates a RASSF1A-dependent DNA damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF Signalling and DNA Damage: Monitoring the Integrity of the Genome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Ras association domain family 1C protein stimulates human lung cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Ras-association domain family 1 protein, RASSF1C, is an IGFBP-5 binding partner and a potential regulator of osteoblast cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Control of microtubule stability by the RASSF1A tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Tumor suppressor RASSF1A is a microtubule-binding protein that stabilizes microtubules and induces G2/M arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RAN GTPase is a RASSF1A effector involved in controlling microtubule organization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1A Suppresses Cell Migration through Inactivation of HDAC6 and Increase of Acetylated α-Tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Epigenetic silencing of RASSF1A deregulates cytoskeleton and promotes malignant behavior of adrenocortical carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Aurora A regulates prometaphase progression by inhibiting the ability of RASSF1A to suppress APC-Cdc20 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Transcriptional regulation of cyclin A2 by RASSF1A through the enhanced binding of p120E4F to the cyclin A2 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1A mediates p21Cip1/Waf1-dependent cell cycle arrest and senescence through modulation of the Raf-MEK-ERK pathway and inhibition of Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Progressive changes in adherens junction structure during intestinal adenoma formation in Apc mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Loss of Rassf1a cooperates with Apc(Min) to accelerate intestinal tumourigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Dynamics of RASSF1A/MOAP-1 association with death receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Identification of a novel Ras-regulated proapoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF1A isoform of RASSF1 promotes microtubule stability and suppresses tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Tumor suppressor Ras-association domain family 1 isoform A is a novel regulator of cardiac hypertrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1A: a potential novel therapeutic target against cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Megaoesophagus in Rassf1a-null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Targeted polyubiquitylation of RASSF1C by the Mule and SCFβ-TrCP ligases in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Tissue factor pathway inhibitor-2 may interact with nuclear protein RASSF1C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The Ras effector RASSF2 is a novel tumor-suppressor gene in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Extracellular signal-regulated kinase 2 (ERK-2) mediated phosphorylation regulates nucleo-cytoplasmic shuttling and cell growth control of Ras-associated tumor suppressor protein, RASSF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The Ras effector RASSF2 controls the PAR-4 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Role of the tumor suppressor RASSF2 in regulation of MST1 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Silencing of RASSF3 by DNA hypermethylation is associated with tumorigenesis in somatotroph adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF3 downregulation increases malignant phenotypes of non-small cell lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF3 candidate tumor suppressor induces apoptosis and G1-S cell-cycle arrest via p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Alveolar rhabdomyosarcoma-associated PAX3-FOXO1 promotes tumorigenesis via Hippo pathway suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Identification of Nore1 as a potential Ras effector

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Deficiency of Rap1-binding protein RAPL causes lymphoproliferative disorders through mislocalization of p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF6 is a novel member of the RASSF family of tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Haplotype mapping of the bronchiolitis susceptibility locus near IL8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF6 tumor suppressor protein regulates apoptosis and the cell cycle via MDM2 protein and p53 protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Gene expression patterns in pancreatic tumors, cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

DNA microarray analysis of pancreatic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Global expression changes of constitutive and hormonally regulated genes during endometrial neoplastic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

PPM1D is a potential therapeutic target in ovarian clear cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phosphorylated-MKK7

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Identification of RASSF8 as a candidate lung tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

14-3-3 proteins: key regulators of cell division, signalling and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

14-3-3 mediated regulation of the tumor suppressor protein, RASSF1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

P-CIP1, a novel protein that interacts with the cytosolic domain of peptidylglycine alpha-amidating monooxygenase, is associated with endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Novel proteins that interact with the COOH-terminal cytosolic routing determinants of an integral membrane peptide-processing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

A novel role of RASSF9 in maintaining epidermal homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Epigenetic inactivation of the RASSF10 candidate tumor suppressor gene is a frequent and an early event in gliomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Frequent epigenetic inactivation of RASSF10 in thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Epigenetic down regulation of RASSF10 and its possible clinical implication in prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF10 is epigenetically silenced and functions as a tumor suppressor in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

DNA methylation presents distinct binding sites for human transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Quantitative DNA methylation analyses reveal stage dependent DNA methylation and association to clinico-pathological factors in breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Reactivation of RASSF1A in breast cancer cells by curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1A and NORE1A methylation and BRAFV600E mutations in thyroid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Combined BubR1 protein down-regulation and RASSF1A hypermethylation in Wilms tumors with diverse cytogenetic changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF1A tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Infliximab use in children and adolescents with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Inflammatory bowel disease: cause and immunobiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

NF-kappaB, an evolutionarily conserved mediator of immune and inflammatory responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Frequent RASSF1A promoter hypermethylation and K-ras mutations in pancreatic carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Promoter Methylation in Prostate Cancer and its Application for the Early Detection of Prostate Cancer Using Serum and Urine Samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Detection of breast cancer in nipple aspirate fluid by CpG island hypermethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

High RASSF1A promoter methylation levels are predictive of poor prognosis in fine-needle aspirate washings of breast cancer lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Elevated plasma levels of hypermethylated RASSF1A gene sequences in pregnant women with intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Frequent epigenetic inactivation of RASSF2 in thyroid cancer and functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF2 hypermethylation is present and related to shorter survival in squamous cervical cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The growth and tumor suppressors NORE1A and RASSF1A are targets for calpain-mediated proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF6 expression in adipocytes is down-regulated by interaction with macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF10 promoter hypermethylation is frequent in malignant melanoma of the skin but uncommon in nevus cell nevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Methylation of RASSF1A gene promoter is regulated by p53 and DAXX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

miR-7 and miR-218 epigenetically control tumor suppressor genes RASSF1A and Claudin-6 by targeting HoxB3 in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The intronic long noncoding RNA ANRASSF1 recruits PRC2 to the RASSF1A promoter, reducing the expression of RASSF1A and increasing cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

RASSF1 Polymorphisms in Cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Oncomirs - microRNAs with a role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

MicroRNAs in biological processes and carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

miRBase: integrating microRNA annotation and deep-sequencing data

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

MicroRNA-602 regulating tumor suppressive gene RASSF1A is overexpressed in hepatitis B virus-infected liver and hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

miR-373 negatively regulates methyl-CpG-binding domain protein 2 (MBD2) in hilar cholangiocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Methyl-CpG binding protein MBD2 is implicated in methylation-mediated suppression of miR-373 in hilar cholangiocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

MicroRNAs and epigenetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Skp2 regulates the antiproliferative function of the tumor suppressor RASSF1A via ubiquitin-mediated degradation at the G1-S transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The tumour suppressor RASSF1A is a novel substrate of PKC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Aurora B-mediated phosphorylation of RASSF1A maintains proper cytokinesis by recruiting Syntaxin16 to the midzone and midbody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Mitotic arrest by tumor suppressor RASSF1A is regulated via CHK1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Ubiquitin ligases and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Cullin-4A·DNA damage-binding protein 1 E3 ligase complex targets tumor suppressor RASSF1A for degradation during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Tumor suppressor RASSF1A promoter: p53 binding and methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The RASSF1A tumor suppressor activates Bax via MOAP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

When RASSF1A RAN into tumor suppression: Ran GTPase is a RASSF1A effector involved in controlling microtubule organization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Comparative analysis of interactions of RASSF1-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The tumor suppressor RASSF1A is a novel effector of small G protein Rap1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The cellular apoptosis susceptibility CAS/CSE1L gene protects ovarian cancer cells from death by suppressing RASSF1C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Loss of RASSF2 Enhances Tumorigencity of Lung Cancer Cells and Confers Resistance to Chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Growth and tumor suppressor NORE1A is a regulatory node between Ras signaling and microtubule nucleation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Mdm2 associates with Ras effector NORE1 to induce the degradation of oncoprotein HIPK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Nore1B regulates TCR signaling via Ras and Carma1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Characterization of interactions of adapter protein RAPL/Nore1B with RAP GTPases and their role in T cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Epstein-Barr virus latent membrane protein 1 increases genomic instability through Egr-1-mediated up-regulation of activation-induced cytidine deaminase in B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulate

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

The tumor suppressor RASSF10 is upregulated upon contact inhibition and frequently epigenetically silenced in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Estimating transcription factor bindability on DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041

Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.02.041