Oncomirs - microRNAs with a role in cancer (Q27860773)

MicroRNAs: genomics, biogenesis, mechanism, and function

Europe PubMed Central

title

Oncomirs - microRNAs with a role in cancer (English)

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author name string

Aurora Esquela-Kerscher

series ordinal

1

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language of work or name

English

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publication date

April 2006

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published in

Nature Reviews Cancer

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volume

6

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page(s)

259-69

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issue

4

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cites work

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31 March 2020

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Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA

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Control of leaf morphogenesis by microRNAs

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A biochemical framework for RNA silencing in plants

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MicroRNA-directed cleavage of HOXB8 mRNA

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The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

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The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation

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Control of developmental timing in Caenorhabditis elegans

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

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The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor

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Control of developmental timing by micrornas and their targets

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The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs.

31 March 2020

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The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target.

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bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila

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Inhibition of translational initiation by Let-7 MicroRNA in human cells

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Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

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Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

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MicroRNA maturation: stepwise processing and subcellular localization

31 March 2020

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Human let-7 stem-loop precursors harbor features of RNase III cleavage products

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The nuclear RNase III Drosha initiates microRNA processing

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Sequence requirements for micro RNA processing and function in human cells

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The Microprocessor complex mediates the genesis of microRNAs

31 March 2020

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Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

31 March 2020

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Processing of primary microRNAs by the Microprocessor complex

31 March 2020

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Nuclear export of microRNA precursors

31 March 2020

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

31 March 2020

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Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

31 March 2020

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

31 March 2020

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

31 March 2020

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

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The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans.

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Heterochronic mutants of the nematode Caenorhabditis elegans.

31 March 2020

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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA

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Identification of novel genes coding for small expressed RNAs

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

31 March 2020

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An extensive class of small RNAs in Caenorhabditis elegans

31 March 2020

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Identification of tissue-specific microRNAs from mouse

31 March 2020

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The small RNA profile during Drosophila melanogaster development

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A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans

31 March 2020

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New microRNAs from mouse and human

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Computational identification of Drosophila microRNA genes

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Vertebrate microRNA genes

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The microRNAs of Caenorhabditis elegans

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Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity

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The Drosophila MicroRNA Mir-14 Suppresses Cell Death and Is Required for Normal Fat Metabolism

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MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode.

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Phylogenetic shadowing and computational identification of human microRNA genes

31 March 2020

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Identification of hundreds of conserved and nonconserved human microRNAs

31 March 2020

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Identification of mammalian microRNA host genes and transcription units

31 March 2020

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Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes

31 March 2020

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Functional siRNAs and miRNAs Exhibit Strand Bias

31 March 2020

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Asymmetry in the assembly of the RNAi enzyme complex

31 March 2020

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Specificity of microRNA target selection in translational repression

31 March 2020

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The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3'UTR

31 March 2020

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Principles of microRNA-target recognition

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The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans

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Combinatorial microRNA target predictions

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Fast and effective prediction of microRNA/target duplexes

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Human MicroRNA targets

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A combined computational-experimental approach predicts human microRNA targets

31 March 2020

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MicroRNA targets in Drosophila

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Computational identification of microRNA targets.

31 March 2020

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Identification of Drosophila MicroRNA targets

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Prediction of mammalian microRNA targets

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Architecture of a validated microRNA::target interaction.

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Common logic of transcription factor and microRNA action

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Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

31 March 2020

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Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

31 March 2020

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Dicer is essential for formation of the heterochromatin structure in vertebrate cells

31 March 2020

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Dicer is essential for mouse development

31 March 2020

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The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

31 March 2020

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Aberrant T cell differentiation in the absence of Dicer.

31 March 2020

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Dicer is required for embryonic angiogenesis during mouse development

31 March 2020

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The microRNA world: small is mighty

31 March 2020

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Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas

31 March 2020

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Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation

31 March 2020

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Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

31 March 2020

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RAS is regulated by the let-7 microRNA family

31 March 2020

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Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

31 March 2020

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MicroRNA gene expression deregulation in human breast cancer

31 March 2020

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Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia

31 March 2020

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MicroRNAs regulate brain morphogenesis in zebrafish

31 March 2020

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MicroRNAs modulate hematopoietic lineage differentiation

31 March 2020

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A pancreatic islet-specific microRNA regulates insulin secretion

31 March 2020

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MicroRNA-143 regulates adipocyte differentiation

31 March 2020

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The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development

31 March 2020

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Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis

31 March 2020

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Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

31 March 2020

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miR-15 and miR-16 induce apoptosis by targeting BCL2

31 March 2020

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A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

31 March 2020

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An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues

31 March 2020

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MicroRNA expression profiles classify human cancers

31 March 2020

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Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

31 March 2020

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Extensive modulation of a set of microRNAs in primary glioblastoma

31 March 2020

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MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells

31 March 2020

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Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression.

31 March 2020

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Multiple proto-oncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events

31 March 2020

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bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA

31 March 2020

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High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma

31 March 2020

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Accumulation of miR-155 and BIC RNA in human B cell lymphomas

31 March 2020

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BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas

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High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma

31 March 2020

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A microRNA polycistron as a potential human oncogene

31 March 2020

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c-Myc-regulated microRNAs modulate E2F1 expression

31 March 2020

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Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma

31 March 2020

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MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

31 March 2020

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A microRNA cluster as a target of genomic amplification in malignant lymphoma.

31 March 2020

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A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma

31 March 2020

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Gains of 13q are correlated with a poor prognosis in liposarcoma

31 March 2020

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A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation

31 March 2020

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Sibling rivalry in the E2F family

31 March 2020

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Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: identification of three independent regions

31 March 2020

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MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation

31 March 2020

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Microarray-based, high-throughput gene expression profiling of microRNAs

31 March 2020

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A custom microarray platform for analysis of microRNA gene expression

31 March 2020

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A microRNA array reveals extensive regulation of microRNAs during brain development

31 March 2020

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Microarray analysis of microRNA expression in the developing mammalian brain

31 March 2020

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Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation

31 March 2020

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Regulation of miRNA expression during neural cell specification

31 March 2020

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Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs

31 March 2020

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MicroRNA profiling of the murine hematopoietic system

31 March 2020

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Probing microRNAs with microarrays: tissue specificity and functional inference

31 March 2020

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Silencing of microRNAs in vivo with 'antagomirs'

31 March 2020

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Short interfering RNAs as a tool for cancer gene therapy

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Antisense therapy for cancer

31 March 2020

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The role of microRNA genes in papillary thyroid carcinoma

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31 March 2020

Identifiers

DOI

10.1038/NRC1840

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

79490

1030226923

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79490

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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