Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer? (Q26828997)

main subject

acute myeloid leukemia

2 references

3 April 2019

11 August 2020

1 reference

2 references

11 August 2020

22 January 2021

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Carolyn S Grove

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

1 reference

August 2014

1 reference

Disease Models & Mechanisms

1 August 2014

3 references

3 April 2019

11 August 2020

22 January 2021

5 references

3 April 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

11 August 2020

22 January 2021

7

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

8

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

941-951

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution

13 June 2020

copyright license

3 references

3 April 2019

11 August 2020

22 January 2021

0 references

on focus list of Wikimedia project

ScienceSource

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cites work

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Clonal evolution in cancer

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7 April 2017

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Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

7 April 2017

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The origin and evolution of mutations in acute myeloid leukemia

7 April 2017

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The life history of 21 breast cancers

7 April 2017

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Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

7 April 2017

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

7 April 2017

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Mutation in TET2 in myeloid cancers

7 April 2017

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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

7 April 2017

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Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

25 May 2017

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Genomic applications in the clinic: use in treatment paradigm of acute myeloid leukemia

28 September 2017

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Survival and cure of acute myeloid leukaemia in England, 1971-2006: a population-based study

28 September 2017

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28 September 2017

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28 September 2017

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Clonal evolution and devolution after chemotherapy in adult acute myelogenous leukemia

28 September 2017

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28 September 2017

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Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

28 September 2017

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Clonal architecture of secondary acute myeloid leukemia

28 September 2017

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28 September 2017

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Dnmt3a is essential for hematopoietic stem cell differentiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Acute leukemia incidence and patient survival among children and adults in the United States, 2001-2007.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

The replication rate of human hematopoietic stem cells in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Chromosomal minimal critical regions in therapy-related leukemia appear different from those of de novo leukemia by high-resolution aCGH.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Stem cells and the aging hematopoietic system

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Coexistence of quiescent and active adult stem cells in mammals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Rate, molecular spectrum, and consequences of human mutation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

The incidence of and mortality from leukaemias in the UK: a general population-based study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Hematopoiesis is not clonal in healthy elderly women.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Differential contributions of haematopoietic stem cells to foetal and adult haematopoiesis: insights from functional analysis of transcriptional regulators.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Biology and management of relapsed acute myeloid leukaemia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

The roles of FLT3 in hematopoiesis and leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

PML/RARalpha and FLT3-ITD induce an APL-like disease in a mouse model

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Chromosome translocations and covert leukemic clones are generated during normal fetal development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Clonal stability of blood cell lineages indicated by X-chromosomal transcriptional polymorphism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Plasmacytomagenesis in mice: model of neoplastic development dependent upon chromosomal translocations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Novel insights into the pathogenesis of the Graffi murine leukemia retrovirus

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Interstrain differences in susceptibility to liver carcinogenesis initiated by N-nitrosodiethylamine and its promotion by phenobarbital in C57BL/6NCr, C3H/HeNCrMTV- and DBA/2NCr mice

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Axl, a prognostic and therapeutic target in acute myeloid leukemia mediates paracrine crosstalk of leukemia cells with bone marrow stroma

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

JAK2 46/1 haplotype is associated with JAK2 V617F-positive myeloproliferative neoplasms in Japanese patients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Cancer survival and prevalence in Australia: period estimates from 1982 to 2010.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Modelling the evolution of genetic instability during tumour progression

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Clonal architecture of chronic myelomonocytic leukemias

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

DNA replication timing and selection shape the landscape of nucleotide variation in cancer genomes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Chromatin organization is a major influence on regional mutation rates in human cancer cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Genetic variegation of clonal architecture and propagating cells in leukaemia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Aneuploidy acts both oncogenically and as a tumor suppressor

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Genetic predisposition to pre-B lymphomas in SL/Kh strain mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

The genetic origin of drug resistance in neoplasms: implications for systemic therapy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4107323

Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia

28 November 2018

1 reference

12 December 2020

AML1/ETO fusion mRNA can be detected in remission blood samples of all patients with t(8;21) acute myeloid leukemia after chemotherapy or autologous bone marrow transplantation

1 reference

12 December 2020

Reasons for treating secondary AML as de novo AML

1 reference

12 December 2020

Five new pedigrees with inherited RUNX1 mutations causing familial platelet disorder with propensity to myeloid malignancy

1 reference

12 December 2020

JAK2V617F allele burden, JAK2 46/1 haplotype and clinical features of Chinese with myeloproliferative neoplasms

1 reference

12 December 2020

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia

1 reference

12 December 2020

Genetic diagnosis by comparative genomic hybridization in adult de novo acute myelocytic leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1242/DMM.015974

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

release_43c4bf2vbzhrpp7nv7dbrc6hue

13 June 2020

Fatcat ID

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25056697%20AND%20SRC:MED&resulttype=core&format=json