Stabilization of neurotoxic soluble beta-sheet-rich conformations of the Alzheimer's disease amyloid-beta peptide (Q24654919)

7

object named as

Colin L Masters

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author name string

Deborah J Tew

1

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Stephen P Bottomley

2

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Giuseppe D Ciccotosto

4

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Jeffrey Babon

5

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Mark G Hinds

6

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Roberto Cappai

8

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Kevin J Barnham

Amyloid plaque core protein in Alzheimer disease and Down syndrome

9

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language of work or name

English

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publication date

1 April 2008

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published in

Biophysical Journal

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volume

94

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page(s)

2752-66

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issue

7

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cites work

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Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

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What is the dominant Abeta species in human brain tissue? A review

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Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains

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Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity

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A specific amyloid-beta protein assembly in the brain impairs memory

7 April 2017

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

7 April 2017

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

7 April 2017

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

7 April 2017

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Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants

7 April 2017

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Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics

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Mechanism of thioflavin T binding to amyloid fibrils.

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Residues 17-20 and 30-35 of beta-amyloid play critical roles in aggregation

28 September 2017

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Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

28 September 2017

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Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation

28 September 2017

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Spontaneous Aggregation and Cytotoxicity of the β-Amyloid Aβ1–40: A Kinetic Model

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Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

28 September 2017

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The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

28 September 2017

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Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

28 September 2017

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Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

28 September 2017

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Solution structures of micelle-bound amyloid beta-(1-40) and beta-(1-42) peptides of Alzheimer's disease

28 September 2017

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Neutron diffraction of alpha, beta and gamma cyclodextrins: hydrogen bonding patterns

28 September 2017

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28 September 2017

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Copper, iron and zinc in Alzheimer's disease senile plaques.

30 May 2018

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Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease.

30 May 2018

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30 May 2018

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Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

30 May 2018

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Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.

30 May 2018

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NMR studies of amyloid beta-peptides: proton assignments, secondary structure, and mechanism of an alpha-helix----beta-sheet conversion for a homologous, 28-residue, N-terminal fragment

30 May 2018

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Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.

30 May 2018

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Secondary structure and interfacial aggregation of amyloid-beta(1-40) on sodium dodecyl sulfate micelles.

30 May 2018

1 reference

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Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

28 November 2018

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Trace metal contamination initiates the apparent auto-aggregation, amyloidosis, and oligomerization of Alzheimer's Abeta peptides.

28 November 2018

1 reference

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Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid

28 November 2018

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A slowly formed transient conformer of Abeta(1-40) is toxic to inward channels of dissociated hippocampal and cortical neurons of rats.

28 November 2018

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

28 November 2018

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DICHROWEB: an interactive website for the analysis of protein secondary structure from circular dichroism spectra.

28 November 2018

1 reference

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A simple way to measure protein refolding rates in water

28 November 2018

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Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy

28 November 2018

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Amyloidogenicity and neurotoxicity of peptides corresponding to the helical regions of PrP(C).

28 November 2018

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Substitutions at codon 22 of Alzheimer's abeta peptide induce diverse conformational changes and apoptotic effects in human cerebral endothelial cells.

28 November 2018

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Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

28 November 2018

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Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype.

28 November 2018

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Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

28 November 2018

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Perturbation of a tertiary hydrogen bond in barstar by mutagenesis of the sole His residue to Gln leads to accumulation of at least one equilibrium folding intermediate.

28 November 2018

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Clusterin (apoJ) alters the aggregation of amyloid beta-peptide (A beta 1-42) and forms slowly sedimenting A beta complexes that cause oxidative stress.

28 November 2018

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Estimation of globular protein secondary structure from circular dichroism.

28 November 2018

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Structural studies of soluble oligomers of the Alzheimer beta-amyloid peptide

28 November 2018

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12 December 2020

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

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12 December 2020

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12 December 2020

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12 December 2020

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Crossref

https://api.crossref.org/works/10.1529%2FBIOPHYSJ.107.119909

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1529/BIOPHYSJ.107.119909

0 references

Fatcat ID

release_bav2u534sfcxfkpuucnwj47zrq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bav2u534sfcxfkpuucnwj47zrq

24 November 2022