SecA, a remarkable nanomachine (Q24631210)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21479870%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

review article

2 references

2 November 2020

SecA, a remarkable nanomachine (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21479870%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

0 references

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2 November 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21479870%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Arnold J.M Driessen

series ordinal

2

1 reference

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28 January 2020

author name string

Arnold J M Driessen

series ordinal

2

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language of work or name

English

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publication date

10 April 2011

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Cellular and Molecular Life Sciences

28 January 2020

1 June 2011

1 reference

2 November 2020

6 references

28 September 2019

20 November 2019

28 November 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21479870%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2 November 2020

68

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28 January 2020

page(s)

2053-2066

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28 January 2020

issue

12

1 reference

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https://scigraph.springernature.com/pub.10.1007/s00018-011-0681-y

28 January 2020

exact match

0 references

cites work

Preprotein-controlled catalysis in the helicase motor of SecA

1 reference

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Structure of the E. coli protein-conducting channel bound to a translating ribosome

7 April 2017

1 reference

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Lateral opening of a translocon upon entry of protein suggests the mechanism of insertion into membranes

7 April 2017

1 reference

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Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

7 April 2017

1 reference

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Conformational transition of Sec machinery inferred from bacterial SecYE structures

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Structure of a complex of the ATPase SecA and the protein-translocation channel

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Ribosome binding of a single copy of the SecY complex: implications for protein translocation

7 April 2017

1 reference

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Structural Basis for Signal-Sequence Recognition by the Translocase Motor SecA as Determined by NMR

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Structure of dimeric SecA, the Escherichia coli preprotein translocase motor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

X-ray structure of a protein-conducting channel

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Structural determinants of SecB recognition by SecA in bacterial protein translocation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Nucleotide control of interdomain interactions in the conformational reaction cycle of SecA

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Major domain swiveling revealed by the crystal structures of complexes of E. coli Rep helicase bound to single-stranded DNA and ADP

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Three-dimensional structure of the bacterial protein-translocation complex SecYEG

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Cross-talk between catalytic and regulatory elements in a DEAD motor domain is essential for SecA function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The DEAD-box protein family of RNA helicases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Energetics of SecA dimerization

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The oligomeric state and arrangement of the active bacterial translocon

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Orientation of SecA and SecB in complex, derived from disulfide cross-linking

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SnapShot: key numbers in biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecA: a tale of two protomers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecB--a chaperone dedicated to protein translocation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Signal peptides are allosteric activators of the protein translocase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Bacterial Sec protein transport is rate-limited by precursor length: a single turnover study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The lateral gate of SecYEG opens during protein translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecA, the motor of the secretion machine, binds diverse partners on one interactive surface

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Protein translocation across the bacterial cytoplasmic membrane.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Bacterial protein secretion through the translocase nanomachine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Pushing, pulling and trapping--modes of motor protein supported protein translocation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The active ring-like structure of SecA revealed by electron crystallography: conformational change upon interaction with SecB.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The SecY translocation complex: convergence of genetics and structure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Selective photoaffinity labeling identifies the signal peptide binding domain on SecA

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Different modes of SecY-SecA interactions revealed by site-directed in vivo photo-cross-linking

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The plug domain of yeast Sec61p is important for efficient protein translocation, but is not essential for cell viability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

27 September 2017

Mechanisms of helicases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecA dimer cross-linked at its subunit interface is functional for protein translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Probing the affinity of SecA for signal peptide in different environments

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Modeling the effects of prl mutations on the Escherichia coli SecY complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Investigating the SecY plug movement at the SecYEG translocation channel.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Dimeric SecA is essential for protein translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Targeting proteins to membranes: structure of the signal recognition particle.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Structure and function of SecA, the preprotein translocase nanomotor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

RecA-like motor ATPases--lessons from structures

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

A large conformational change of the translocation ATPase SecA

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Nucleotide and Phospholipid-Dependent Control of PPXD and C-Domain Association for SecA ATPase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecA-dependent quality control of intracellular protein localization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Nucleotide binding induces changes in the oligomeric state and conformation of Sec A in a lipid environment: a small-angle neutron-scattering study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Binding, activation and dissociation of the dimeric SecA ATPase at the dimeric SecYEG translocase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Ring-like pore structures of SecA: implication for bacterial protein-conducting channels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Dissociation of the dimeric SecA ATPase during protein translocation across the bacterial membrane

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Complex behavior in solution of homodimeric SecA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The SecYEG preprotein translocation channel is a conformationally dynamic and dimeric structure

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Role of the cytoplasmic segments of Sec61alpha in the ribosome-binding and translocation-promoting activities of the Sec61 complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecYEG assembles into a tetramer to form the active protein translocation channel

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The PrlA and PrlG phenotypes are caused by a loosened association among the translocase SecYEG subunits

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Mapping an interface of SecY (PrlA) and SecE (PrlG) by using synthetic phenotypes and in vivo cross-linking

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

PrlA4 prevents the rejection of signal sequence defective preproteins by stabilizing the SecA-SecY interaction during the initiation of translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The catalytic cycle of the escherichia coli SecA ATPase comprises two distinct preprotein translocation events

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The molecular chaperone SecB is released from the carboxy-terminus of SecA during initiation of precursor protein translocation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Mechanisms of helicase-catalyzed DNA unwinding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Characterization of a potential catalytic residue, Asp-133, in the high affinity ATP-binding site of Escherichia coli SecA, translocation ATPase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

prlA suppressors in Escherichia coli relieve the proton electrochemical gradient dependency of translocation of wild-type precursors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Residues essential for the function of SecE, a membrane component of the Escherichia coli secretion apparatus, are located in a conserved cytoplasmic region

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

In vivo studies of the role of SecA during protein export in Escherichia coli

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Two distinct ATP-binding domains are needed to promote protein export by Escherichia coli SecA ATPase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Processing in vivo of precursor maltose-binding protein in Escherichia coli occurs post-translationally as well as co-translationally.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Complementation of two overlapping fragments of SecA, a protein translocation ATPase of Escherichia coli, allows ATP binding to its amino-terminal region

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Proton transfer is rate-limiting for translocation of precursor proteins by the Escherichia coli translocase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Autogenous translation regulation by Escherichia coli ATPase SecA may be mediated by an intrinsic RNA helicase activity of this protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Suppressor analysis suggests a multistep, cyclic mechanism for protein secretion in Escherichia coli

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

What drives the translocation of proteins?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Immobilization of the plug domain inside the SecY channel allows unrestricted protein translocation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Maximal efficiency of coupling between ATP hydrolysis and translocation of polypeptides mediated by SecB requires two protomers of SecA

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Full-length Escherichia coli SecA dimerizes in a closed conformation in solution as determined by cryo-electron microscopy.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Identification of the preprotein binding domain of SecA.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecB modulates the nucleotide-bound state of SecA and stimulates ATPase activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Membrane deinsertion of SecA underlying proton motive force-dependent stimulation of protein translocation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Signal sequence recognition in posttranslational protein transport across the yeast ER membrane.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Stepwise movement of preproteins in the process of translocation across the cytoplasmic membrane of Escherichia coli.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The spontaneous insertion of proteins into and across membranes: the helical hairpin hypothesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Translocation of ProOmpA possessing an intramolecular disulfide bridge into membrane vesicles of Escherichia coli. Effect of membrane energization

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The ATPase activity of SecA is regulated by acidic phospholipids, SecY, and the leader and mature domains of precursor proteins

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

ΔμH+ and ATP function at different steps of the catalytic cycle of preprotein translocase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Precursor protein translocation by the Escherichia coli translocase is directed by the protonmotive force

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecA supports a constant rate of preprotein translocation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

The proton motive force lowers the level of ATP required for the in vitro translocation of a secretory protein in Escherichia coli.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecA, an essential component of the secretory machinery of Escherichia coli, exists as homodimer.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

SecA promotes preprotein translocation by undergoing ATP-driven cycles of membrane insertion and deinsertion.

30 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The bacterial protein-translocation complex: SecYEG dimers associate with one or two SecA molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The oligomeric distribution of SecYEG is altered by SecA and translocation ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Architecture of the protein-conducting channel associated with the translating 80S ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Protein translocation is mediated by oligomers of the SecY complex with one SecY copy forming the channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Membrane topology inversion of SecG detected by labeling with a membrane-impermeable sulfhydryl reagent that causes a close association of SecG with SecA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Arginine 357 of SecY is needed for SecA-dependent initiation of preprotein translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Deregulation of the SecYEG translocation channel upon removal of the plug domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The active protein-conducting channel of Escherichia coli contains an apolar patch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Zinc stabilizes the SecB binding site of SecA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The C terminus of SecA is involved in both lipid binding and SecB binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Global co-ordination of protein translocation by the SecA IRA1 switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The long alpha-helix of SecA is important for the ATPase coupling of translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Structural biology: Clamour for a kiss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

SecA, the peripheral subunit of the Escherichia coli precursor protein translocase, is functional as a dimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Covalently dimerized SecA is functional in protein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The bacterial ATPase SecA functions as a monomer in protein translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Phospholipid-induced monomerization and signal-peptide-induced oligomerization of SecA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Additional in vitro and in vivo evidence for SecA functioning as dimers in the membrane: dissociation into monomers is not essential for protein translocation in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Asymmetric binding between SecA and SecB two symmetric proteins: implications for function in export.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Sites of interaction between SecA and the chaperone SecB, two proteins involved in export

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Nucleotide exchange from the high-affinity ATP-binding site in SecA is the rate-limiting step in the ATPase cycle of the soluble enzyme and occurs through a specialized conformational state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Bacterial sec-translocase unfolds and translocates a class of folded protein domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Charged amino acids in a preprotein inhibit SecA-dependent protein translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

A role for the two-helix finger of the SecA ATPase in protein translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

In vivo membrane topology of Escherichia coli SecA ATPase reveals extensive periplasmic exposure of multiple functionally important domains clustering on one face of SecA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Mutations in the Sec61p Channel Affecting Signal Sequence Recognition and Membrane Protein Topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Oligomeric Rings of the Sec61p Complex Induced by Ligands Required for Protein Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The Structure of Ribosome-Channel Complexes Engaged in Protein Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Escherichia coli SecA shape and dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Structural determinants of lateral gate opening in the protein translocon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

A molecular switch in SecA protein couples ATP hydrolysis to protein translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

Disorder-order folding transitions underlie catalysis in the helicase motor of SecA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-011-0681-Y

The Bacterial SRP Receptor, SecA and the Ribosome Use Overlapping Binding Sites on the SecY Translocon

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101351

Targeting and assembly of periplasmic and outer-membrane proteins in Escherichia coli

28 November 2018

1 reference

12 December 2020

The bacterial SecY/E translocation complex forms channel-like structures similar to those of the eukaryotic Sec61p complex

1 reference

12 December 2020

Identification of Two Interaction Sites in SecY that Are Important for the Functional Interaction with SecA

1 reference

12 December 2020

A novel dimer interface and conformational changes revealed by an X-ray structure of B. subtilis SecA

1 reference

12 December 2020

The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain

1 reference

12 December 2020

Allosteric effects of nucleotide cofactors on Escherichia coli Rep helicase-DNA binding

1 reference

12 December 2020

The aqueous pore through the translocon has a diameter of 40-60 A during cotranslational protein translocation at the ER membrane

1 reference

12 December 2020

Preprotein transfer to the Escherichia coli translocase requires the co‐operative binding of SecB and the signal sequence to SecA

1 reference

12 December 2020

Determining the conductance of the SecY protein translocation channel for small molecules

1 reference

12 December 2020

Delta psi stimulates membrane translocation of the C-terminal part of a signal sequence

1 reference

12 December 2020

Quaternary Structure of SecA in Solution and Bound to SecYEG Probed at the Single Molecule Level

1 reference

12 December 2020

10.1007/S00018-011-0681-Y

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21479870%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 January 2020

1047179892

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21479870%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2 references