Liver x receptors in atherosclerosis and inflammation (Q24608256)

Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia

Europe PubMed Central

title

Liver x receptors in atherosclerosis and inflammation (English)

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Seung-Soon Im

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Timothy F Osborne

series ordinal

2

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language of work or name

English

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publication date

15 April 2011

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published in

Circulation Research

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volume

108

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issue

8

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page(s)

996-1001

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cites work

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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

7 April 2017

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Synthetic LXR ligand inhibits the development of atherosclerosis in mice

7 April 2017

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7 April 2017

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Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

7 April 2017

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

7 April 2017

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Gout-associated uric acid crystals activate the NALP3 inflammasome

7 April 2017

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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

7 April 2017

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International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D recept

7 April 2017

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The liver X receptor (LXR) and hepatic lipogenesis. The carbohydrate-response element-binding protein is a target gene of LXR

7 April 2017

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Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

7 April 2017

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Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

7 April 2017

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Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

7 April 2017

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An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

7 April 2017

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Non-redundant roles for LXRalpha and LXRbeta in atherosclerosis susceptibility in low density lipoprotein receptor knockout mice

7 April 2017

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

7 April 2017

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Molecular mediators of hepatic steatosis and liver injury

7 April 2017

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

7 April 2017

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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

7 April 2017

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Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

7 April 2017

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Liver x receptor signaling pathways and atherosclerosis

27 September 2017

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Control of macrophage activation and function by PPARs

27 September 2017

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A feed-forward loop amplifies nutritional regulation of PNPLA3

27 September 2017

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Macrophage death and defective inflammation resolution in atherosclerosis

27 September 2017

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Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

27 September 2017

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Bile acids as regulatory molecules

27 September 2017

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LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse

27 September 2017

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TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis

27 September 2017

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SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice

27 September 2017

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FXR: a metabolic regulator and cell protector

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Liver X receptor stimulates cholesterol efflux and inhibits expression of proinflammatory mediators in human airway smooth muscle cells

27 September 2017

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Lipoproteins, macrophage function, and atherosclerosis: beyond the foam cell?

27 September 2017

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A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

LXR-dependent gene expression is important for macrophage survival and the innate immune response

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Autoregulation of the human liver X receptor alpha promoter

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Role of oxidized low density lipoprotein in atherogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Defective mer receptor tyrosine kinase signaling in bone marrow cells promotes apoptotic cell accumulation and accelerates atherosclerosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Liver X receptor agonists suppress vascular smooth muscle cell proliferation and inhibit neointima formation in balloon-injured rat carotid arteries

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Increased susceptibility of thymocytes to apoptosis in mice lacking AIM, a novel murine macrophage-derived soluble factor belonging to the scavenger receptor cysteine-rich domain superfamily

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3082200

Coronary atherosclerosis: determinants of plaque rupture

28 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21493922