The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression (Q24536056)

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7 January 2020

title

The MLL fusion gene, MLL-AF4, regulates cyclin-dependent kinase inhibitor CDKN1B (p27kip1) expression (English)

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7 January 2020

6

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7 January 2020

author name string

Zhen-Biao Xia

1

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7 January 2020

Relja Popovic

2

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7 January 2020

Jing Chen

3

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7 January 2020

Catherine Theisler

4

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7 January 2020

Tara Stuart

5

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7 January 2020

Frank Erfurth

7

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7 January 2020

Manuel O Diaz

8

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7 January 2020

Nancy J Zeleznik-Le

9

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7 January 2020

language of work or name

English

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publication date

16 September 2005

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7 January 2020

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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7 January 2020

volume

102

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7 January 2020

issue

39

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7 January 2020

page(s)

14028-14033

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Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

7 January 2020

cites work

1 reference

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Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

24 March 2017

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MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein

24 March 2017

1 reference

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

24 March 2017

1 reference

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Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein

24 March 2017

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24 March 2017

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Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis

24 March 2017

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p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

24 March 2017

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MLL targets SET domain methyltransferase activity to Hox gene promoters

24 March 2017

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ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

24 March 2017

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Altered Hox expression and segmental identity in Mll-mutant mice

7 April 2017

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7 April 2017

Recycling the Cell Cycle

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Mechanisms controlling pathogenesis and survival of leukemic stem cells

22 April 2017

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MLL fusion partners AF4 and AF9 interact at subnuclear foci

27 September 2017

1 reference

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Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias

27 September 2017

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Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties

27 September 2017

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The role of MLL in hematopoiesis and leukemia

27 September 2017

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Cell cycle regulators and hematopoiesis

27 September 2017

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MAD1 and p27(KIP1) cooperate to promote terminal differentiation of granulocytes and to inhibit Myc expression and cyclin E-CDK2 activity

27 September 2017

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The MT domain of the proto-oncoprotein MLL binds to CpG-containing DNA and discriminates against methylation

27 September 2017

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p27(Kip1) is an inducer of intestinal epithelial cell differentiation

27 September 2017

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27 September 2017

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27 September 2017

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The role of chromosome translocations in leukemogenesis.

27 September 2017

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Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia.

27 September 2017

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Establishment and characterization of a megakaryoblast cell line with amplification of MLL.

27 September 2017

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Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL.

27 September 2017

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High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

27 September 2017

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Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

27 September 2017

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

27 September 2017

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27 September 2017

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Rearrangement of the MLL gene confers a poor prognosis in childhood acute lymphoblastic leukemia, regardless of presenting age.

27 September 2017

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11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene

27 September 2017

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Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

27 September 2017

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Molecular cloning and characterization of the human p27Kip1 gene promoter

27 September 2017

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Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines

30 May 2018

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Hematologic malignancies with t(4;11)(q21;q23)--a cytogenetic, morphologic, immunophenotypic and clinical study of 183 cases. European 11q23 Workshop participants.

30 May 2018

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Deletion analysis of p16(INKa) and p15(INKb) in relapsed childhood acute lymphoblastic leukemia.

21 January 2018

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MLL-mediated transcriptional gene regulation investigated by gene expression profiling.

21 January 2018

1 reference

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Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

21 January 2018

1 reference

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Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.

21 January 2018

1 reference

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Reduced expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27(Kip1) in human colon cancer

29 November 2018

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12 December 2020

STAT3-mediated differentiation and survival and of myeloid cells in response to granulocyte colony-stimulating factor: role for the cyclin-dependent kinase inhibitor p27(Kip1)

1 reference

12 December 2020

Down-regulation of p27Kip1 expression is required for development and function of T cells

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12 December 2020

Cell cycle-independent upregulation of p27Kip1 by p21Waf1 in K562 cells

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12 December 2020

BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1)

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12 December 2020

Localization and expression of p27KIP1 in multistage colorectal carcinogenesis

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0506464102

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1635040

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16169901%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

7 January 2020

ADS bibcode

2005PNAS..10214028X

0 references

1635040

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16169901%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference