ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage (Q24336416)

cellular response to DNA damage stimulus

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Naoe Taira

1

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Hiroyuki Yamamoto

2

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Tomoko Yamaguchi

3

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Yoshio Miki

4

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Kiyotsugu Yoshida

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

12 February 2010

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published in

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volume

285

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issue

7

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page(s)

4909-19

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2836095/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage

19 March 2017

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Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage

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Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9

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c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage

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Nuclear trafficking of pro-apoptotic kinases in response to DNA damage

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BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress

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MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.

29 November 2018

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Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases

29 November 2018

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The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha)

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