Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A (Q28362375)

7

object named as

T Blundell

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author name string

S Himpel

1

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P Panzer

2

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K Eirmbter

3

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H Czajkowska

4

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M Sayed

5

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L C Packman

6

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H Kentrup

8

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J Grötzinger

9

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H G Joost

The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site

10

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language of work or name

English

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publication date

1 November 2001

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number of pages

9

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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volume

359

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page(s)

497-505

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issue

Pt 3

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cites work

1 reference

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The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation

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Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases

20 March 2017

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Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

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Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

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Activation of androgen receptor function by a novel nuclear protein kinase

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Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

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Functional analysis of the fission yeast Prp4 protein kinase involved in pre-mRNA splicing and isolation of a putative mammalian homologue

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The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers

20 March 2017

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A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

20 March 2017

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

20 March 2017

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A novel mammalian protein kinase gene (mak) is highly expressed in testicular germ cells at and after meiosis

20 March 2017

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

20 March 2017

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Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII

20 March 2017

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Molecular cloning of a novel serine/threonine kinase, MRK, possibly involved in cardiac development

20 March 2017

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Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division

20 March 2017

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A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody

29 September 2017

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Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells.

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Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis.

29 September 2017

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Tyrosine dephosphorylation of glycogen synthase kinase-3 is involved in its extracellular signal-dependent inactivation

29 September 2017

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29 September 2017

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The fission yeast prp4+ gene involved in pre-mRNA splicing codes for a predicted serine/threonine kinase and is essential for growth

29 September 2017

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Contributions of mass spectrometry to peptide and protein structure

29 September 2017

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Autophosphorylation in vitro of recombinant 42-kilodalton mitogen-activated protein kinase on tyrosine

29 September 2017

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Saccharomyces cerevisiae Yak1p protein kinase autophosphorylates on tyrosine residues and phosphorylates myelin basic protein on a C-terminal serine residue

29 September 2017

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The serine, threonine, and/or tyrosine-specific protein kinases and protein phosphatases of prokaryotic organisms: a family portrait

2 June 2018

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minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila.

2 June 2018

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Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase

2 June 2018

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Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis

2 June 2018

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Metabolism of Pro-Luteinizing Hormone-Releasing Hormone in Immortalized Hypothalamic Neurons*

2 June 2018

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High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.

2 June 2018

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Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.

27 November 2018

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YakA, a protein kinase required for the transition from growth to development in Dictyostelium.

27 November 2018

1 reference

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Glycogen synthase kinase-3 beta is a dual specificity kinase differentially regulated by tyrosine and serine/threonine phosphorylation.

27 November 2018

1 reference

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Specificity determinants of substrate recognition by the protein kinase DYRK1A

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11672423