VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage (Q24329080)

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7 March 2020

title

VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damage (English)

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7 March 2020

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Marta Vázquez-Cedeira

3

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Alejandro Carrillo-Jiménez

7 March 2020

6

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7 March 2020

Pedro A. Lazo

7

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7 March 2020

author name string

Inmaculada López-Sánchez

1

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7 March 2020

Alberto Valbuena

2

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7 March 2020

Jyoti Khadake

4

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7 March 2020

Marta Sanz-García

5

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7 March 2020

language of work or name

English

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publication date

31 January 2014

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7 March 2020

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7 March 2020

volume

588

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7 March 2020

page(s)

692-700

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issue

5

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Blinded by the Light: The Growing Complexity of p53

7 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The expanding universe of p53 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

p53 in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

p53 and E2f: partners in life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The first 30 years of p53: growing ever more complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

p53 Stabilization and accumulation induced by human vaccinia-related kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

p53 downregulates its activating vaccinia-related kinase 1, forming a new autoregulatory loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Regulation by phosphorylation of the relative affinities of the N-terminal transactivation domains of p53 for p300 domains and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Molecular mechanism of the interaction between MDM2 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Cooperative regulation of p53 by modulation of ternary complex formation with CBP/p300 and HDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Characterization of three paralogous members of the Mammalian vaccinia related kinase family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Caenorhabditis elegans BAF-1 and its kinase VRK-1 participate directly in post-mitotic nuclear envelope assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Genome-wide analysis of germ cell proliferation in C.elegans identifies VRK-1 as a key regulator of CEP-1/p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

c-Jun phosphorylation by the human vaccinia-related kinase 1 (VRK1) and its cooperation with the N-terminal kinase of c-Jun (JNK)

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Macro histone H2A1.2 (macroH2A1) protein suppresses mitotic kinase VRK1 during interphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Downregulation of VRK1 by p53 in response to DNA damage is mediated by the autophagic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Alteration of the VRK1-p53 autoregulatory loop in human lung carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Roles of VRK1 as a new player in the control of biological processes required for cell division.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Human VRK1 is an early response gene and its loss causes a block in cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Rewiring of human lung cell lineage and mitotic networks in lung adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Molecular genetic analysis of VRK1 in mammary epithelial cells: depletion slows proliferation in vitro and tumor growth and metastasis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mice deficient in the serine/threonine protein kinase VRK1 are infertile due to a progressive loss of spermatogonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The kinase VRK1 is required for normal meiotic progression in mammalian oogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Defective folliculogenesis in female mice lacking Vaccinia-related kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Substrate profiling of human vaccinia-related kinases identifies coilin, a Cajal body nuclear protein, as a phosphorylation target with neurological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Kinetic properties of p53 phosphorylation by the human vaccinia-related kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Sensitivity of the kinase activity of human vaccinia-related kinase proteins to toxic metals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

NMR solution structure of human vaccinia-related kinase 1 (VRK1) reveals the C-terminal tail essential for its structural stability and autocatalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Shaping genetic alterations in human cancer: the p53 mutation paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mutant p53: one name, many proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Cytoscape: a software environment for integrated models of biomolecular interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

The DNA Damage Response: Making It Safe to Play with Knives

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

21 January 2018

p53 mutations in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

Mutant p53: an oncogenic transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

When mutants gain new powers: news from the mutant p53 field.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

Tumour suppression by p53: a role for the DNA damage response?

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

The tumor suppressor p53: from structures to drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

Posttranslational modification of p53: cooperative integrators of function

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

Mutant p53 gain-of-function in cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

The origins and evolution of the p53 family of genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

p63 and p73, the ancestors of p53.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

VRK1 phosphorylates CREB and mediates CCND1 expression

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2014.01.040

7 January 2021

10.1016/J.FEBSLET.2014.01.040

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

533055

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7 March 2020

533055

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

533055

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24492002%20AND%20SRC:MED&resulttype=core&format=json