The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1 (Q24316909)

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1 January 2020

title

The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1 (English)

1 reference

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Nei like DNA glycosylase 1

1 January 2020

main subject

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Werner syndrome RecQ like helicase

GOA release 2020-03-11

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negative regulation of nuclease activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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5

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12

Vilhelm A Bohr

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1 January 2020

author name string

Aditi Das

1

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1 January 2020

Istvan Boldogh

2

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1 January 2020

Jae Wan Lee

3

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1 January 2020

Jeanine A Harrigan

4

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1 January 2020

Jason Piotrowski

6

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1 January 2020

Nadja de Souza Pinto

7

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1 January 2020

William Ramos

8

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1 January 2020

Marc M Greenberg

9

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1 January 2020

Tapas K Hazra

10

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Sankar Mitra

11

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1 January 2020

language of work or name

English

0 references

publication date

3 July 2007

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1 January 2020

number of pages

12

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Journal of Biological Chemistry

inferred from page(s)

published in

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1 January 2020

volume

282

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page(s)

26591-26602

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issue

36

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Oxidants, antioxidants, and the degenerative diseases of aging

1 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Reactions of oxyl radicals with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Oxidative stress: free radical production in neural degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Decreased base excision repair and increased helicase activity in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Base excision repair of DNA in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Long-patch DNA repair synthesis during base excision repair in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

AP endonuclease-independent DNA base excision repair in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Repair of Oxidized Bases in DNA Bubble Structures by Human DNA Glycosylases NEIL1 and NEIL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Roles of the Werner syndrome protein in pathways required for maintenance of genome stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Genetics and the pathobiology of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Genetic analysis of ageing: role of oxidative damage and environmental stresses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Current advances in unraveling the function of the Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Regulation of WRN helicase activity in human base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Homologous recombination resolution defect in werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Werner syndrome protein contains three structure-specific DNA binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Induction of the human oxidized base-specific DNA glycosylase NEIL1 by reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Physical and functional interaction between DNA ligase IIIalpha and poly(ADP-Ribose) polymerase 1 in DNA single-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

High mobility group protein-1 (HMG-1) is a unique activator of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The interaction of FBPase with aldolase: a kinetic and fluorescence investigation on chicken muscle enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Biochemical characterization of a low molecular weight aspartic protease inhibitor from thermo-tolerant Bacillus licheniformis: kinetic interactions with Pepsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Synthesis of oligonucleotides containing Fapy.dG (N6-(2-deoxy-alpha,beta-D-erythro-pentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Endogenous oxidative DNA base modifications analysed with repair enzymes and GC/MS technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Detection of recurrent chromosome abnormalities in Ewing's sarcoma and peripheral neuroectodermal tumor cells using bivariate flow karyotyping

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Mast Cell Degranulation RequiresN-Ethylmaleimide-Sensitive Factor-Mediated SNARE Disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The Werner syndrome protein is a DNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Werner helicase is localized to transcriptionally active nucleoli of cycling cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The novel DNA glycosylase, NEIL1, protects mammalian cells from radiation-mediated cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Pathways and functions of the Werner syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Stimulation of DNA glycosylase activity of OGG1 by NEIL1: functional collaboration between two human DNA glycosylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

WRN helicase expression in Werner syndrome cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

DNA damage-induced translocation of the Werner helicase is regulated by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Werner protein protects nonproliferating cells from oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates NEIL1 glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

Spontaneous and induced chromosomal instability in Werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

7 January 2021

Multiple involvement of oxidative stress in Werner syndrome phenotype

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

7 January 2021

Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

7 January 2021

Passing the baton in base excision repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

7 January 2021

Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

7 January 2021

Mucking with metabolism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703343200

7 January 2021

Identifiers

DOI

10.1074/JBC.M703343200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611195%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference