Regulation of WRN helicase activity in human base excision repair (Q45072750)

9 December 2017

Regulation of WRN helicase activity in human base excision repair (English)

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9 December 2017

5

Vilhelm A Bohr

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9 December 2017

Byungchan Ahn

1

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9 December 2017

Jeanine A Harrigan

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2

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9 December 2017

Fred E Indig

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3

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9 December 2017

David M Wilson

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4

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9 December 2017

language of work or name

English

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publication date

22 September 2004

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Journal of Biological Chemistry

9 December 2017

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9 December 2017

279

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9 December 2017

53465-53474

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9 December 2017

51

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Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

9 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Junction of RecQ helicase biochemistry and human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Homologous recombination resolution defect in werner syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Generation of single-nucleotide repair patches following excision of uracil residues from DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Molecular mechanism of PCNA-dependent base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Mammalian base excision repair by DNA polymerases delta and epsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

AP endonuclease-independent DNA base excision repair in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

DNA repair and mutagenesis in Werner syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Biochemical characterization of the WRN-FEN-1 functional interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Werner syndrome protein contains three structure-specific DNA binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

A quantitative model of human DNA base excision repair. I. Mechanistic insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Two distinct human DNA diesterases that hydrolyze 3′-blocking deoxyribose fragments from oxidized DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Instability and decay of the primary structure of DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

The role of Mg2+ and specific amino acid residues in the catalytic reaction of the major human abasic endonuclease: new insights from EDTA-resistant incision of acyclic abasic site analogs and site-directed mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Acetylation of human AP-endonuclease 1, a critical enzyme in DNA repair and transcription regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

AP endonuclease 1 coordinates flap endonuclease 1 and DNA ligase I activity in long patch base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Werner syndrome protein is regulated and phosphorylated by DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

Properties of a Recombinant Human Uracil-DNA Glycosylase from the UNG Gene and Evidence that UNG Encodes the Major Uracil-DNA Glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409624200

21 January 2018

Identifiers

DOI

10.1074/JBC.M409624200

1 reference

9 December 2017

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