Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse (Q24312915)

exocytosis

1 reference

Synaptotagmin-like 2

1 reference

Synaptotagmin-like protein 1

1 reference

RAB27A, member RAS oncogene family

1 reference

Tiziana Daniele

5

0 references

Gillian Griffiths

object named as

Gillian M Griffiths

10

0 references

Mitsunori Fukuda

object named as

Mitsunori Fukuda

9

0 references

Maurizio Aricò

1 reference

ORCID Public Data File 2021

author name string

Oliver Holt

1

0 references

Eiko Kanno

2

0 references

Giovanna Bossi

3

0 references

Sarah Booth

4

0 references

Alessandra Santoro

6

0 references

Maurizio Arico

7

0 references

Chika Saegusa

Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4

8

0 references

language of work or name

English

0 references

publication date

April 2008

0 references

published in

Traffic

0 references

volume

9

0 references

issue

4

0 references

page(s)

446-57

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Novel Munc13-4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

How synaptotagmin promotes membrane fusion.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Identification of an organelle receptor for myosin-Va

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Rab27a regulates the peripheral distribution of melanosomes in melanocytes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Involvement of Rab27 in antigen-induced histamine release from rat basophilic leukemia 2H3 cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

The small GTPase Rab27B regulates amylase release from rat parotid acinar cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

PEST sequences and regulation by proteolysis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Regulation of membrane fusion in synaptic excitation-secretion coupling: speed and accuracy matter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Secretory mechanisms in cell-mediated cytotoxicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Rab27a is a key component of the secretory machinery of azurophilic granules in granulocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Rab27 and its effectors in secretory granule exocytosis: a novel docking machinery composed of a Rab27.effector complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Granuphilin molecularly docks insulin granules to the fusion machinery.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Rab GTPases and myosin motors in organelle motility

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

A general role for Rab27a in secretory cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

The actin-binding domain of Slac2-a/melanophilin is required for melanosome distribution in melanocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

Molecular determinants of protein half-lives in eukaryotic cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2329822

The immunological synapse of CTL contains a secretory domain and membrane bridges.

30 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

Centrosome polarization delivers secretory granules to the immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

Slac2-a/melanophilin contains multiple PEST-like sequences that are highly sensitive to proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

Distinct Rab27A binding affinities of Slp2-a and Slac2-a/melanophilin: Hierarchy of Rab27A effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

Munc13-4 is a GTP-Rab27-binding protein regulating dense core granule secretion in platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

The Slp4-a linker domain controls exocytosis through interaction with Munc18-1.syntaxin-1a complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0854.2008.00714.X

Getting Secretory Granules Ready for Prime Time

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18266782

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1600-0854.2008.00714.X

1 reference

4388617

4388617

1 reference

1 reference

1 reference