Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion (Q24312200)

GOA release 2020-03-11

catenin beta 1

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positive regulation of cell-cell adhesion mediated by cadherin

GOA release 2020-03-11

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GOA release 2020-03-11

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He-Xin Yan

1

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Wen Yang

2

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Rui Zhang

3

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Lei Chen

4

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Liang Tang

5

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Bo Zhai

6

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Shu-Qin Liu

7

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Hui-Fang Cao

8

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Xiao-Bo Man

9

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Hong-Ping Wu

10

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Meng-Chao Wu

11

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Hong-Yang Wang

Journal of Biological Chemistry

12

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language of work or name

English

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publication date

2 June 2006

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published in

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volume

281

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page(s)

15423-33

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issue

22

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cites work

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Structural and evolutionary relationships among protein tyrosine phosphatase domains

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Genomic structure and alternative splicing of murine R2B receptor protein tyrosine phosphatases (PTPkappa, mu, rho and PCP-2)

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Receptor protein tyrosine phosphatases: involvement in cell-cell interaction and signaling

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Inactivation of the E-cadherin-mediated cell adhesion system in human cancers

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Cadherins and catenins in development

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Beta-catenin as oncogene: the smoking gun.

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The promise and perils of Wnt signaling through beta-catenin.

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Identification of c-MYC as a target of the APC pathway

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.

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Convergence of Wnt, beta-catenin, and cadherin pathways

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Dynamic interaction of PTPmu with multiple cadherins in vivo

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Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo

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Association of Human Protein-tyrosine Phosphatase κ with Members of the Armadillo Family

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Physical and functional interaction between receptor-like protein tyrosine phosphatase PCP-2 and beta-catenin

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The oncogenic activation of beta-catenin

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E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner

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Phosphorylation and free pool of beta-catenin are regulated by tyrosine kinases and tyrosine phosphatases during epithelial cell migration.

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E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity

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Inhibition of beta-catenin-mediated transactivation by cadherin derivatives

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Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway

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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

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The transmembrane protein-tyrosine phosphatase LAR modulates signaling by multiple receptor tyrosine kinases

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The transmembrane protein-tyrosine phosphatase CD45 is associated with decreased insulin receptor signaling

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CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

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Protein tyrosine phosphatase genes downregulated in melanoma

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

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Receptor tyrosine phosphatase psi is required for Delta/Notch signalling and cyclic gene expression in the presomitic mesoderm

21 January 2018

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