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catenin beta 1 (Q1634046)

From Wikidata
mammalian protein found in Homo sapiens
  • catenin beta-1
  • catenin (cadherin-associated protein), beta 1, 88kDa
  • Beta-catenin
  • CTNNB1
  • CTNNB1 protein, human
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    English
    catenin beta 1
    mammalian protein found in Homo sapiens
    • catenin beta-1
    • catenin (cadherin-associated protein), beta 1, 88kDa
    • Beta-catenin
    • CTNNB1
    • CTNNB1 protein, human

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    155 references
    retrieved
    1 January 2018
    stated in
    Loss of δ-catenin function in severe autism
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Regulation and function of the interaction between the APC tumour suppressor protein and EB1
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Transmembrane protein 170B is a novel breast tumorigenesis suppressor gene that inhibits the Wnt/β-catenin pathway
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    GSKIP, an inhibitor of GSK3beta, mediates the N-cadherin/beta-catenin pool in the differentiation of SH-SY5Y cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The ubiquitin ligase RNF220 enhances canonical Wnt signaling through USP7-mediated deubiquitination of β-catenin
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Paxillin-beta-catenin interactions are involved in Rac/Cdc42-mediated endothelial barrier-protective response to oxidized phospholipids
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Endosomal adaptor proteins APPL1 and APPL2 are novel activators of beta-catenin/TCF-mediated transcription
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Cdx2 Controls Expression of the Protocadherin Mucdhl, an Inhibitor of Growth and β-Catenin Activity in Colon Cancer Cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Cited1 is a bifunctional transcriptional cofactor that regulates early nephronic patterning
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The Presenilin 1 Protein Is a Component of a High Molecular Weight Intracellular Complex That Contains β-Catenin
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    beta-Catenin is a Nek2 substrate involved in centrosome separation
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    E-cadherin regulates human Nanos1, which interacts with p120ctn and induces tumor cell migration and invasion
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    TC1 (C8orf4) enhances the Wnt/beta-catenin pathway by relieving antagonistic activity of Chibby
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Forkhead box F2 suppresses gastric cancer through a novel FOXF2-IRF2BPL-β-catenin signaling axis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Novel membrane protein shrew-1 targets to cadherin-mediated junctions in polarized epithelial cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Oncogenic Function of DACT1 in Colon Cancer through the Regulation of β-catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    LZTFL1 suppresses gastric cancer cell migration and invasion through regulating nuclear translocation of β-catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    VE-cadherin and beta-catenin binding dynamics during histamine-induced endothelial hyperpermeability
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Proteomic and genomic analysis of PITX2 interacting and regulating networks
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Structural basis of coactivation of liver receptor homolog-1 by  -catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Large-scale structural analysis of the classical human protein tyrosine phosphatome
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Beta-catenin affects androgen receptor transcriptional activity and ligand specificity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Role of TAZ as mediator of Wnt signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The X protein of hepatitis B virus binds to the F box protein Skp2 and inhibits the ubiquitination and proteasomal degradation of c-Myc
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Nuclear IGF1R is a transcriptional co-activator of LEF1/TCF
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    IpaC of Shigella binds to the C-terminal domain of beta-catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Molecular basis of actin reorganization promoted by binding of enterohaemorrhagic Escherichia coli EspB to alpha-catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A Protein Interaction between β-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    E-cadherin is required for caveolin-1-mediated down-regulation of the inhibitor of apoptosis protein survivin via reduced beta-catenin-Tcf/Lef-dependent transcription
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The neurotransmitter dopamine modulates vascular permeability in the endothelium
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A human interactome in three quantitative dimensions organized by stoichiometries and abundances
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    In silico prediction of physical protein interactions and characterization of interactome orphans
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assays
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Kaiso is a bimodal modulator for Wnt/beta-catenin signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Identification of paxilin domains interacting with β‐catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Huntingtin interacting proteins are genetic modifiers of neurodegeneration
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The beta-catenin binding protein ICAT modulates androgen receptor activity
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Functional interaction of DNA topoisomerase IIalpha with the beta-catenin and T-cell factor-4 complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The protein interaction landscape of the human CMGC kinase group
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    α-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-κB signalling.
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    RET modulates cell adhesion via its cleavage by caspase in sympathetic neurons
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Nucleo-cytoplasmic shuttling of human Kank protein accompanies intracellular translocation of beta-catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Structure of a human Tcf4-beta-catenin complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Telomerase modulates Wnt signalling by association with target gene chromatin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    E-cadherin regulates the association between beta-catenin and actinin-4
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    TGIF Governs a Feed-Forward Network that Empowers Wnt Signaling to Drive Mammary Tumorigenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The EDD E3 ubiquitin ligase ubiquitinates and up-regulates β-catenin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Chromatin protein HMGB2 regulates articular cartilage surface maintenance via beta-catenin pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    miR-182-5p promotes hepatocellular carcinoma progression by repressing FOXO3a
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Yap1 acts downstream of α-catenin to control epidermal proliferation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    IQGAP1 interacts with components of the slit diaphragm complex in podocytes and is involved in podocyte migration and permeability in vitro
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    MicroRNA-566 activates EGFR signaling and its inhibition sensitizes glioblastoma cells to nimotuzumab
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    beta-Catenin regulates excitatory postsynaptic strength at hippocampal synapses
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Biosensor-based micro-affinity purification for the proteomic analysis of protein complexes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    β‐catenin regulates parathyroid hormone/parathyroid hormone–related protein receptor signals and chondrocyte hypertrophy through binding to the intracellular C‐terminal region of the receptor
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Lipid phosphate phosphatase 3 stabilization of beta-catenin induces endothelial cell migration and formation of branching point structures
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Targeting androgen receptor in estrogen receptor-negative breast cancer
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Bidirectional cross-regulation between the endothelial nitric oxide synthase and β-catenin signalling pathways
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Kindlin 2 forms a transcriptional complex with β-catenin and TCF4 to enhance Wnt signalling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Loss of ephrin-A5 function disrupts lens fiber cell packing and leads to cataract
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Bcr interferes with beta-catenin-Tcf1 interaction
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The RNA aptamer disrupts protein-protein interaction between beta-catenin and nuclear factor-kappaB p50 and regulates the expression of C-reactive protein
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    YAP/TAZ incorporation in the β-catenin destruction complex orchestrates the Wnt response
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The Tumor-Suppressor WWOX and HDAC3 Inhibit the Transcriptional Activity of the β-Catenin Coactivator BCL9-2 in Breast Cancer Cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The Krüppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/beta-catenin signaling pathway
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Receptor tyrosine phosphatase PTPγ is a regulator of spinal cord neurogenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Microsomal prostaglandin E synthase-1 promotes hepatocarcinogenesis through activation of a novel EGR1/β-catenin signaling axis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The kinase TNIK is an essential activator of Wnt target genes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A specific domain in α-catenin mediates binding to β-catenin or plakoglobin
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The transmembrane receptor protein tyrosine phosphatase DEP1 interacts with p120(ctn)
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Parafibromin/Hyrax activates Wnt/Wg target gene transcription by direct association with beta-catenin/Armadillo
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Control of chromosome stability by the beta-TrCP-REST-Mad2 axis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Tcf4 can specifically recognize beta-catenin using alternative conformations
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Vitamin D receptor is essential for normal keratinocyte stem cell function
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The third 20 amino acid repeat is the tightest binding site of APC for beta-catenin
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    VE-cadherin and beta-catenin binding dynamics during histamine-induced endothelial hyperpermeability
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    transcription coactivator activity
    determination method or standard
    IBA
    IDA
    IEA
    IMP
    7 references
    retrieved
    1 January 2018
    stated in
    Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IMP
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Chromatin-specific regulation of LEF-1–β-catenin transcription activation and inhibition in vitro
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IBA
    cadherin binding
    determination method or standard
    HDA
    IBA
    IEA
    IPI
    7 references
    retrieved
    1 January 2018
    stated in
    Characterization of Cadherin-24, a Novel Alternatively Spliced Type II Cadherin
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    VE-cadherin and beta-catenin binding dynamics during histamine-induced endothelial hyperpermeability
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IPI
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    InterPro
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IBA
    retrieved
    1 January 2018
    stated in
    E-cadherin interactome complexity and robustness resolved by quantitative proteomics
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    HDA
    cell component
    cytoplasm
    determination method or standard
    IDA
    IEA
    12 references
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumours
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    WNT7a induces E-cadherin in lung cancer cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Frizzled-9 is activated by Wnt-2 and functions in Wnt/beta -catenin signaling
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Radixin regulates cell migration and cell-cell adhesion through Rac1
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton
    GOA
    curator
    Community Assessment of Community Annotation with Ontologies
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    nucleus
    determination method or standard
    IDA
    IEA
    12 references
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    Transmembrane protein 170B is a novel breast tumorigenesis suppressor gene that inhibits the Wnt/β-catenin pathway
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    The inner nuclear membrane protein emerin regulates beta-catenin activity by restricting its accumulation in the nucleus
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Issues associated with assessing nuclear localization of N-terminally unphosphorylated beta-catenin with monoclonal antibody 8E7
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Constitutive activation of the Wnt canonical pathway in mantle cell lymphoma
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Prognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancer
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    catenin complex
    determination method or standard
    IBA
    IDA
    IEA
    6 references
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    Cadherin 26 is an alpha integrin-binding epithelial receptor regulated during allergic inflammation
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IBA
    biological process
    positive regulation of transcription by RNA polymerase II
    determination method or standard
    IDA
    ISS
    TAS
    IMP
    IEA
    10 references
    retrieved
    14 February 2017
    stated in
    The regulation and deregulation of Wnt signaling by PARK genes in health and disease
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    TAS
    retrieved
    14 February 2017
    stated in
    Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    TAS
    retrieved
    14 February 2017
    stated in
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    ISS
    retrieved
    14 February 2017
    stated in
    FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    IMP
    retrieved
    14 February 2017
    stated in
    Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    IMP
    retrieved
    14 February 2017
    stated in
    A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    IMP
    retrieved
    14 February 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    IEA
    retrieved
    14 February 2017
    stated in
    Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    IDA
    retrieved
    14 February 2017
    stated in
    Chromatin-specific regulation of LEF-1–β-catenin transcription activation and inhibition in vitro
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    IDA
    retrieved
    14 February 2017
    stated in
    Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P35222
    determination method or standard
    IDA
    positive regulation of transcription by RNA polymerase II
    determination method or standard
    IBA
    IDA
    IEA
    IMP
    ISS
    TAS
    13 references
    retrieved
    1 January 2018
    stated in
    The regulation and deregulation of Wnt signaling by PARK genes in health and disease
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    TAS
    retrieved
    1 January 2018
    stated in
    Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    TAS
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Parkinsons Disease Gene Ontology Initiative
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    ISS
    retrieved
    1 January 2018
    stated in
    FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IMP
    retrieved
    1 January 2018
    stated in
    A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IMP
    retrieved
    1 January 2018
    stated in
    Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IMP
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Chromatin-specific regulation of LEF-1–β-catenin transcription activation and inhibition in vitro
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IBA
    canonical Wnt signaling pathway
    determination method or standard
    IDA
    IEA
    IMP
    6 references
    retrieved
    1 January 2018
    stated in
    TBL1-TBLR1 and beta-catenin recruit each other to Wnt target-gene promoter for transcription activation and oncogenesis
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IMP
    retrieved
    1 January 2018
    stated in
    Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IMP
    retrieved
    1 January 2018
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IEA
    retrieved
    1 January 2018
    stated in
    WNT7a induces E-cadherin in lung cancer cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Issues associated with assessing nuclear localization of N-terminally unphosphorylated beta-catenin with monoclonal antibody 8E7
    GOA
    curator
    UniProt
    UniProt protein ID
    P35222
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    retrieved
    1 January 2018
    stated in
    Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription
    GOA
    curator
    British Heart Foundation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35222
    determination method or standard
    IDA
    Commons category
    Beta-Catenin
    0 references

    Identifiers

    MeSH descriptor ID
    C495270
    subject named as
    CTNNB1 protein, human
    0 references
    Ensembl protein ID
    PDB structure ID
     
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                  Retrieved from "https://www.wikidata.org/w/index.php?title=Q1634046&oldid=2506097195"