RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization (Q24308703)

GOA release 2020-03-11

protein ubiquitination

1 reference

11

Ze'ev Ronai

0 references

Limor Broday

2

Limor Broday

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Christine Didier

1

Christine Didier

0 references

Scott C Henderson

Scott Henderson

9

0 references

Shoichi Takahashi

5

Shoichi Takahashi

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author name string

Anindita Bhoumik

3

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Sharon Israeli

4

0 references

Koh Nakayama

6

0 references

Sheila M Thomas

7

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Christopher E Turner

8

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Hisataka Sabe

Molecular and Cellular Biology

10

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language of work or name

English

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publication date

August 2003

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published in

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volume

23

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page(s)

5331-45

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issue

15

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cites work

An ADP-ribosylation factor GTPase-activating protein Git2-short/KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organization

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Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion

19 March 2017

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

19 March 2017

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A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migration

19 March 2017

1 reference

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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

19 March 2017

1 reference

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Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

19 March 2017

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CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

19 March 2017

1 reference

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Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway

19 March 2017

1 reference

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Characterization of the TGF beta 1-inducible hic-5 gene that encodes a putative novel zinc finger protein and its possible involvement in cellular senescence

19 March 2017

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Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

19 March 2017

1 reference

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

19 March 2017

1 reference

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Cloning, expression and mapping of a novel RING-finger gene (RNF5), a human homologue of a putative zinc-finger gene from Caenorhabditis elegans

19 March 2017

1 reference

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Tyrosine phosphorylation of paxillin, FAK, and p130CAS: effects on cell spreading and migration

19 March 2017

1 reference

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Integrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesions

19 March 2017

1 reference

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The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

19 March 2017

1 reference

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Paxillin and focal adhesion signalling

19 March 2017

1 reference

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19 March 2017

Paxillin interactions

1 reference

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Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin

19 March 2017

1 reference

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Paxillin LD motifs may define a new family of protein recognition domains

19 March 2017

1 reference

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Integrins regulate the association and phosphorylation of paxillin by c-Abl

19 March 2017

1 reference

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Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin

19 March 2017

1 reference

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c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors

19 March 2017

1 reference

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The adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signaling

19 March 2017

1 reference

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Phosphorylation-dependent targeting of c-Jun ubiquitination by Jun N-kinase

19 March 2017

1 reference

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SCF and Cullin/Ring H2-based ubiquitin ligases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

The polycomb group protein EZH2 is involved in progression of prostate cancer

7 April 2017

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Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

7 April 2017

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Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase

7 April 2017

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Paxillin associates with poly(A)-binding protein 1 at the dense endoplasmic reticulum and the leading edge of migrating cells

27 September 2017

1 reference

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Paxillin: a focal adhesion-associated adaptor protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

The LD4 motif of paxillin regulates cell spreading and motility through an interaction with paxillin kinase linker (PKL).

27 September 2017

1 reference

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Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase

27 September 2017

1 reference

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Cbl: many adaptations to regulate protein tyrosine kinases

27 September 2017

1 reference

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Paxillin alpha and Crk-associated substrate exert opposing effects on cell migration and contact inhibition of growth through tyrosine phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

RING domains: master builders of molecular scaffolds?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Specific decrease in the level of Hic-5, a focal adhesion protein, during immortalization of mouse embryonic fibroblasts, and its association with focal adhesion kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Alterations in focal adhesion kinase activity and associated proteins during malignant conversion of mouse keratinocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

RMA1, an Arabidopsis thaliana gene whose cDNA suppresses the yeast sec15 mutation, encodes a novel protein with a RING finger motif and a membrane anchor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Mitosis specific serine phosphorylation and downregulation of one of the focal adhesion protein, paxillin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

The molecular architecture of focal adhesions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Paxillin: a cytoskeletal target for tyrosine kinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Paxillin isoforms in mouse. Lack of the gamma isoform and developmentally specific beta isoform expression.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

In vitro assembly and recognition of Lys-63 polyubiquitin chains

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=165736

Transcriptional up-regulation of paxillin expression by heregulin in human breast cancer cells

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12861019

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.23.15.5331-5345.2003

1 reference

3394225

3394225

1 reference

1 reference

1 reference