Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor (Q24305253)

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English	Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor	scientific article

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29 January 2020

Cyclin-dependent kinase 5 modulates the transcriptional activity of the mineralocorticoid receptor and regulates expression of brain-derived neurotrophic factor (English)

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29 January 2020

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mineralocorticoid

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Cyclin dependent kinase 5 regulatory subunit 1

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GOA release 2020-03-11

cyclin dependent kinase 5

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GOA release 2020-03-11

negative regulation of transcription, DNA-templated

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GOA release 2020-03-11

Mayukh Chakrabarti

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29 January 2020

Georgios P. Chrousos

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George P Chrousos

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29 January 2020

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Tomoshige Kino

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29 January 2020

Howard Jaffe

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29 January 2020

Niranjana D Amin

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29 January 2020

Ya-Li Zheng

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29 January 2020

Harish C Pant

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31 March 2010

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Molecular Endocrinology

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5

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29 January 2020

941-952

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29 January 2020

Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications

1 reference

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19 March 2017

Crystal structure of an ancient protein: evolution by conformational epistasis

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19 March 2017

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

1 reference

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19 March 2017

Intracellular glucocorticoid signaling: a formerly simple system turns stochastic

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19 March 2017

Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase

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19 March 2017

Neurotoxicity induces cleavage of p35 to p25 by calpain

1 reference

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19 March 2017

Cdk5 is essential for synaptic vesicle endocytosis

1 reference

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19 March 2017

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

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19 March 2017

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

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19 March 2017

Steroid receptor heterodimerization demonstrated in vitro and in vivo

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7 April 2017

Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

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7 April 2017

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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7 April 2017

The human glucocorticoid receptor: molecular basis of biologic function

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27 September 2017

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

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27 September 2017

Brain-derived neurotrophic factor, stress and depression: a minireview

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27 September 2017

Glucocorticoids and brain functions.

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27 September 2017

Global profiling of phosphopeptides by titania affinity enrichment

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27 September 2017

Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress

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27 September 2017

Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine

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27 September 2017

Therapy Insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression?

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27 September 2017

Cyclic AMP response element binding protein and brain-derived neurotrophic factor: molecules that modulate our mood?

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27 September 2017

The Smad6-histone deacetylase 3 complex silences the transcriptional activity of the glucocorticoid receptor: potential clinical implications

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27 September 2017

G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus

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27 September 2017

The mechanisms of differential glucocorticoid and mineralocorticoid action in the brain and peripheral tissues

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27 September 2017

Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior

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27 September 2017

Glucocorticoid and mineralocorticoid receptors and associated diseases

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27 September 2017

Neuronal cyclin-dependent kinase 5: role in nervous system function and its specific inhibition by the Cdk5 inhibitory peptide

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27 September 2017

Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles

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27 September 2017

Cdk5 as a drug target for the treatment of Alzheimer's disease

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27 September 2017

Corticosteroids: sculptors of the hippocampal formation

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27 September 2017

Nuclear receptor coactivator p160 proteins enhance the HIV-1 long terminal repeat promoter by bridging promoter-bound factors and the Tat-P-TEFb complex

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27 September 2017

A decade of CDK5.

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27 September 2017

Mice with targeted mutations of glucocorticoid and mineralocorticoid receptors: models for depression and anxiety?

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27 September 2017

Heterodimerization of mineralocorticoid and glucocorticoid receptors at a novel negative response element of the 5-HT1A receptor gene

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27 September 2017

Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease

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27 September 2017

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

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27 September 2017

A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

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27 September 2017

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor

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27 September 2017

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27 September 2017

Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice

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30 May 2018

A role for BDNF in the late-phase of hippocampal long-term potentiation

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30 May 2018

Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators

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30 May 2018

Inescapable versus escapable shock modulates long-term potentiation in the rat hippocampus.

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30 May 2018

Forebrain glucocorticoid receptors modulate anxiety-associated locomotor activation and adrenal responsiveness.

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29 November 2018

The coupling of a trkB tyrosine residue to LTP

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29 November 2018

Elevated neuronal Cdc2-like kinase activity in the Alzheimer disease brain.

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29 November 2018

p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

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29 November 2018

Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus.

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29 November 2018

Psychological stress repeatedly blocks hippocampal primed burst potentiation in behaving rats.

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29 November 2018

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

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29 November 2018

Neuronal cyclin-dependent kinase-5 phosphorylation sites in neurofilament protein (NF-H) are dephosphorylated by protein phosphatase 2A

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12 December 2020

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Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20357208

12 December 2020

based on heuristic

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Reconstitution of the N-terminal transcription activation function of human mineralocorticoid receptor in a defective human glucocorticoid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20357208

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofilaments in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20357208

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain-dependent proteolytic cleavage of the p35 cyclin-dependent kinase 5 activator to p25

1 reference

https://pubmed.ncbi.nlm.nih.gov/20357208

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity characterization of a cdc2-like protein kinase purified from bovine brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20357208

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1210/ME.2009-0395

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29 January 2020

1 reference

Europe PubMed Central

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29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20357208%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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