IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity (Q24301670)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

0 references

Hypoxia inducible factor 1 subunit alpha

1 reference

Cytosolic iron-sulfur assembly component 3

1 reference

Egl-9 family hypoxia inducible factor 1

1 reference

oxygen homeostasis

1 reference

author

Frank S. Lee

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Jianhe Huang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Daisheng Song

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Adrian Flores

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Quan Zhao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Sharon M Mooney

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Leslie M Shaw

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

language of work or name

English

0 references

publication date

1 January 2007

1 reference

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29 December 2019

number of pages

12

1 reference

inferred from page(s)

published in

Biochemical Journal

1 reference

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29 December 2019

volume

401

1 reference

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29 December 2019

issue

1

1 reference

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29 December 2019

page(s)

341-352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).

29 December 2019

cites work

1 reference

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VHL protein-interacting deubiquitinating enzyme 2 deubiquitinates and stabilizes HIF-1alpha

19 March 2017

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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

19 March 2017

1 reference

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Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

19 March 2017

1 reference

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

19 March 2017

1 reference

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

19 March 2017

1 reference

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

19 March 2017

1 reference

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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

19 March 2017

1 reference

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A conserved family of prolyl-4-hydroxylases that modify HIF

19 March 2017

1 reference

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

19 March 2017

1 reference

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HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

19 March 2017

1 reference

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

19 March 2017

1 reference

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Prenylated prelamin A interacts with Narf, a novel nuclear protein

19 March 2017

1 reference

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

19 March 2017

1 reference

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

19 March 2017

1 reference

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Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

19 March 2017

1 reference

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A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

19 March 2017

1 reference

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

19 March 2017

1 reference

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Desulfovibrio desulfuricans iron hydrogenase: the structure shows unusual coordination to an active site Fe binuclear center

19 March 2017

1 reference

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X-ray crystal structure of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum to 1.8 angstrom resolution

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Targeting HIF-1 for cancer therapy

19 March 2017

1 reference

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

19 March 2017

1 reference

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A novel genetic system to detect protein-protein interactions

19 March 2017

1 reference

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The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron-sulphur proteins

19 March 2017

1 reference

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Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity

19 March 2017

1 reference

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

19 March 2017

1 reference

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Regulation of hypoxia-inducible factor 1 by prolyl and asparaginyl hydroxylases

19 March 2017

1 reference

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Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor

19 March 2017

1 reference

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Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

19 March 2017

1 reference

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Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors

19 March 2017

1 reference

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Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein

19 March 2017

1 reference

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Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

19 March 2017

1 reference

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

19 March 2017

1 reference

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Jab1 interacts directly with HIF-1alpha and regulates its stability

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha

19 March 2017

1 reference

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The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

19 March 2017

1 reference

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Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein

19 March 2017

1 reference

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Oxygen sensing by HIF hydroxylases

19 March 2017

1 reference

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

7 April 2017

1 reference

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Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 April 2017

1 reference

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The von Hippel-Lindau protein, HIF hydroxylation, and oxygen sensing

7 April 2017

1 reference

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Dioxygenases as O2-dependent regulators of the hypoxic response pathway

27 September 2017

1 reference

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Signalling hypoxia by HIF hydroxylases

27 September 2017

1 reference

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Negative and positive regulation of HIF-1: a complex network

27 September 2017

1 reference

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Proline hydroxylation and gene expression

27 September 2017

1 reference

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Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1).

27 September 2017

1 reference

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Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells

27 September 2017

1 reference

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Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

27 September 2017

1 reference

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Distinct aerobic and hypoxic mechanisms of HIF-alpha regulation by CSN5

27 September 2017

1 reference

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Hydrogenases: active site puzzles and progress

27 September 2017

1 reference

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Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts

27 September 2017

1 reference

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The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen

27 September 2017

1 reference

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SM-20, EGL-9, and the EGLN family of hypoxia-inducible factor prolyl hydroxylases

27 September 2017

1 reference

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The Interface Between the Biological and Inorganic Worlds: Iron-Sulfur Metalloclusters

27 September 2017

1 reference

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Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex

27 September 2017

1 reference

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Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

27 September 2017

1 reference

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Inhibitory PAS domain protein (IPAS) is a hypoxia-inducible splicing variant of the hypoxia-inducible factor-3alpha locus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Hydrogenases: hydrogen-activating enzymes

27 September 2017

1 reference

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Iron hydrogenases--ancient enzymes in modern eukaryotes.

27 September 2017

1 reference

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Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Classification and phylogeny of hydrogenases

27 September 2017

1 reference

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HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

27 September 2017

1 reference

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I kappa B kinase is critical for TNF-alpha-induced VCAM1 gene expression in renal tubular epithelial cells

27 September 2017

1 reference

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Clostridial iron-sulphur proteins.

27 September 2017

1 reference

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A novel FeS cluster in Fe-only hydrogenases.

27 September 2017

1 reference

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Structure and mechanism of iron-only hydrogenases

27 September 2017

1 reference

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Hydrogenosomes: eukaryotic adaptations to anaerobic environments.

27 September 2017

1 reference

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Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene

27 September 2017

1 reference

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Trichomonas hydrogenosomes contain the NADH dehydrogenase module of mitochondrial complex I.

30 May 2018

1 reference

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Non-mitochondrial complex I proteins in a hydrogenosomal oxidoreductase complex

29 November 2018

1 reference

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

The transcriptional activation function of the HIF-like factor requires phosphorylation at a conserved threonine

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1698691

Hydrogenases in green algae: do they save the algae's life and solve our energy problems?

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16956324

12 December 2020

inferred from PubMed ID database lookup

The transcriptional activity of the APP intracellular domain-Fe65 complex is inhibited by activation of the NF-kappaB pathway

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16956324

12 December 2020

inferred from PubMed ID database lookup

Classification and phylogeny of hydrogenases

1 reference

Crossref

https://api.crossref.org/works/10.1042%2FBJ20060635

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1042/BJ20060635

2 references

Consolidated OpenCitations Corpus – April 2017

3215851

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

3215851

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16956324%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

16956324

2 references

Consolidated OpenCitations Corpus – April 2017

3215851