Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery (Q24298213)

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9 November 2019

title

Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machinery (English)

1 reference

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ATPase H+ transporting V1 subunit H

9 November 2019

main subject

1 reference

GOA release 2020-03-11

endocytosis

1 reference

GOA release 2020-03-11

author

Matthias Geyer

1

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9 November 2019

Oliver T Fackler

6

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9 November 2019

author name string

Haifeng Yu

2

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9 November 2019

Robert Mandic

3

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9 November 2019

Thomas Linnemann

4

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9 November 2019

Yong-Hui Zheng

5

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9 November 2019

B Matija Peterlin

7

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9 November 2019

language of work or name

English

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publication date

24 May 2002

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Journal of Biological Chemistry

9 November 2019

published in

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9 November 2019

volume

277

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9 November 2019

issue

32

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9 November 2019

page(s)

28521-28529

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

9 November 2019

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Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

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Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

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A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

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Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

21 January 2018

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A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

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Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

21 January 2018

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Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

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Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes

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Myristoylation-dependent binding of HIV-1 Nef to CD4.

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Nef-CD4 physical interaction sensed with the yeast two-hybrid system

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The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

21 January 2018

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Linking cargo to vesicle formation: receptor tail interactions with coat proteins.

21 January 2018

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Negative factor from SIV binds to the catalytic subunit of the V-ATPase to internalize CD4 and to increase viral infectivity

21 January 2018

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7 January 2021

Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1074/JBC.M200522200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12032142%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference