A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor (Q28288514)

1

0 references

W Yonemoto

2

0 references

S Ferrell

3

0 references

D Williams-Herman

4

0 references

R Geleziunas

5

0 references

W C Greene

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

6

0 references

publication date

5 November 1998

0 references

language of work or name

0 references

0 references

8

0 references

issue

22

0 references

page(s)

1235-8

0 references

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the chain of adaptor complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Nef Interacts with the μ Subunit of Clathrin Adaptor Complexes and Reveals a Cryptic Sorting Signal in MHC I Molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef. Mapping of the Nef binding surface by NMR.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

A Role for Acidic Residues in Di-leucine Motif-based Targeting to the Endocytic Pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Structure-activity relationship of the leucine-based sorting motifs in the cytosolic tail of the major histocompatibility complex-associated invariant chain

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Nef-mediated Clathrin-coated Pit Formation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

The trans-Golgi network: a late secretory sorting station

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Inhibition of Nef- and phorbol ester-induced CD4 degradation by macrolide antibiotics.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

HIV accessory proteins: leading roles for the supporting cast.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021

Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2807%2900517-9

7 January 2021